Duzela 60 Mg Capsule (10 Cap)

DUZELA 60 MG CAPSULE

Name

Brand Name: Duzela 60 Capsule DR Common Name: Duloxetine Capsule (60mg)

Composition

Duzela 60 MG Capsule contains Duloxetine as its active ingredient, with each capsule providing 60mg of the substance.

Uses

Duzela 60 MG Capsule is primarily used for the treatment of several conditions:

• Depression: Including major depressive disorders.
• Anxiety Disorder: Specifically generalized anxiety disorder.
• Diabetic Nerve Pain (Diabetic Neuropathic Pain): To relieve nerve-related pain in diabetic patients.
• Fibromyalgia: A condition characterized by widespread body pain and tenderness.
• Chronic Musculoskeletal Pain: Such as chronic pain associated with arthritis or back pain.
• Stress Urinary Incontinence: To manage involuntary urine leakage in women.

Dosage and Administration

Duzela 60 MG Capsule should be taken as advised by a doctor. It can be taken with or without food, but it is recommended to take it at a fixed time each day to maintain consistent blood levels. The capsule should be swallowed whole and not chewed, crushed, or broken. Do not stop taking this medicine suddenly, as it can lead to withdrawal symptoms; the dosage should be gradually reduced under medical supervision.

Side Effects

Common side effects may include:

• Nausea, dry mouth, constipation, or diarrhea
• Headache, dizziness, and sleepiness
• Decreased libido, abnormal dreams, blurred vision
• Increased sweating, indigestion, heartburn, stomach pain

Serious side effects can occur, and patients should contact their doctor if they experience restlessness, thoughts of self-harm, sudden mood changes, or persistent troublesome side effects.

Precautions

• Alcohol: Consumption of alcohol with Duzela 60 Capsule is unsafe and should be avoided due to increased risk of drowsiness and liver damage.
• Pregnancy and Breastfeeding: Not recommended during pregnancy and is probably unsafe during breastfeeding; consult a doctor.
• Driving and Operating Machinery: This medicine can cause dizziness and sleepiness, so avoid activities requiring mental alertness until you know how it affects you.
• Medical Conditions: Inform your doctor if you have kidney, liver, or heart problems, a history of seizures (epilepsy), glaucoma, low sodium levels, or a bleeding disorder.
• Drug Interactions: Avoid taking with MAO inhibitors and inform your doctor about all other medications, including antidepressants, anxiolytics, painkillers, and migraine medicines, to prevent serious interactions.

Storage

Store Duzela 60 MG Capsule below 30°C in a cool and dry place, away from direct sunlight and out of the reach of children.

DUZELA 60 MG CAPSULE, containing the active ingredient Duloxetine, is a medication primarily used to manage various mental health conditions and chronic pain.

What is DUZELA 60 MG CAPSULE used for?

DUZELA 60 MG CAPSULE is used to treat major depressive disorder, generalized anxiety disorder, pain associated with diabetic peripheral neuropathy (nerve damage from diabetes), fibromyalgia (widespread muscle pain and stiffness), chronic musculoskeletal pain, and stress urinary incontinence in women.

How does DUZELA 60 MG CAPSULE work?

DUZELA 60 MG CAPSULE works by increasing the levels of certain natural chemical messengers in the brain, specifically serotonin and norepinephrine. These chemicals help to maintain mental balance, improve mood, and interfere with the transmission of pain signals, thereby reducing anxiety, depression, and pain.

What is the usual dosage for DUZELA 60 MG CAPSULE?

The typical dosage of DUZELA 60 MG CAPSULE varies depending on the condition being treated and individual patient response. For many conditions, a common adult dosage is 60 mg once daily. Your doctor might start you on a lower dose, such as 30 mg once daily for a week, to allow your body to adjust before increasing to 60 mg. Doses typically do not exceed 120 mg per day for most conditions.

What are the possible side effects of DUZELA 60 MG CAPSULE?

Common side effects can include nausea, dry mouth, sleepiness, fatigue, constipation, loss of appetite, increased sweating, dizziness, headaches, and diarrhea. Some individuals may also experience sexual side effects or blurred vision.

More serious, but less common, side effects can include liver damage, serotonin syndrome (symptoms like agitation, confusion, rapid heart rate), abnormal bleeding, severe skin reactions, manic episodes in people with bipolar disorder, seizures, or low sodium levels. There is also a boxed warning regarding an increased risk of suicidal thoughts and behaviors, especially in children, adolescents, and young adults.

Is DUZELA 60 MG CAPSULE safe during pregnancy or breastfeeding?

During Pregnancy: DUZELA 60 MG CAPSULE is generally not recommended during pregnancy due to limited information on its effects on the developing baby. If you are pregnant or planning to become pregnant, discuss the risks and benefits with your doctor, as untreated mental health conditions can also pose risks. Taking duloxetine late in pregnancy may lead to temporary withdrawal symptoms or, rarely, breathing problems in the newborn, and a slightly increased risk of bleeding after delivery.

During Breastfeeding: Small amounts of duloxetine pass into breast milk. While some experts consider it acceptable to use cautiously during breastfeeding, an alternative medication might be preferred, especially for newborns or premature infants. It's important to monitor the infant for any signs of drowsiness or poor weight gain.

Can DUZELA 60 MG CAPSULE be taken with other medications?

DUZELA 60 MG CAPSULE can interact with several other medications. It should not be taken with monoamine oxidase inhibitors (MAOIs) due to the risk of a serious condition called serotonin syndrome. Caution is also advised when combining it with other antidepressants (SSRIs, SNRIs, TCAs), blood thinners (like warfarin), nonsteroidal anti-inflammatory drugs (NSAIDs like ibuprofen or aspirin), tramadol, certain antibiotics (like ciprofloxacin), fluvoxamine, and the herbal supplement St. John's Wort. Always inform your doctor about all prescription, over-the-counter medications, and herbal supplements you are taking.

Consuming alcohol while taking this medicine can increase the risk of liver problems.

What precautions should be taken while taking DUZELA 60 MG CAPSULE?

Do not stop taking DUZELA 60 MG CAPSULE abruptly, as this can lead to withdrawal symptoms such as dizziness, nausea, and headaches. This medicine may cause dizziness or drowsiness; therefore, do not drive or operate heavy machinery until you know how it affects you. Inform your doctor if you have liver or kidney disease, heart problems, a history of seizures, bipolar disorder, glaucoma, or low sodium levels. Close monitoring for suicidal thoughts and behaviors is recommended, especially at the beginning of treatment or after dosage adjustments, particularly in younger individuals.

What happens if a dose of DUZELA 60 MG CAPSULE is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose (e.g., less than 12 hours for once-daily dosing or less than 4 hours for twice-daily dosing), skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should DUZELA 60 MG CAPSULE be stored?

Store DUZELA 60 MG CAPSULE in a closed container at room temperature, typically between 15°C and 30°C (59°F and 86°F). Keep it away from excessive heat, moisture, and direct light, and prevent it from freezing. Always store medicine out of the reach of children.