Vildapride M 50/1000 Mg Tablet (10 Tab)

VILDAPRIDE M 50/1000 MG TABLET

VILDAPRIDE M 50/1000 MG TABLET is an oral anti-diabetic medication manufactured by MICRO LABS LIMITED. It is a combination drug used to manage high blood sugar levels in adult patients with Type 2 Diabetes Mellitus.

Composition

Each tablet contains two active ingredients:

• Vildagliptin (50 mg): A Dipeptidyl Peptidase-4 (DPP-4) inhibitor that increases insulin secretion from the pancreas in a glucose-dependent manner and reduces glucagon secretion.
• Metformin (1000 mg): A biguanide that works by reducing glucose production in the liver, decreasing intestinal absorption of glucose, and enhancing insulin sensitivity in the body's cells.

Uses

VILDAPRIDE M 50/1000 MG TABLET is prescribed for:

• Managing high blood sugar levels in adults with Type 2 Diabetes Mellitus.
• Improving blood glucose control when diet and exercise alone, or treatment with either metformin or vildagliptin alone, is insufficient.
• Assisting other diabetes medicines in controlling blood sugar levels.
• Reducing the risk of serious complications associated with diabetes, such as kidney damage, blindness, nerve problems, limb amputations, and cardiovascular events.

Dosage and Administration

• VILDAPRIDE M 50/1000 MG TABLET should be taken exactly as advised by your doctor.
• The dosage varies based on individual factors like the severity of the condition and response to treatment.
• It is generally recommended to take the tablet with meals to minimize stomach upset.
• Typically, it is prescribed for twice-daily administration.
• Swallow the tablet whole; do not crush, chew, or break it.
• Do not stop taking this medicine without consulting your doctor, as abrupt discontinuation can lead to increased blood sugar levels and complications.
• Regular monitoring of blood sugar levels is advised during treatment.

Side Effects

Common side effects may include:

• Headache
• Dizziness
• Nausea and Vomiting
• Diarrhea and Stomach pain
• Fatigue
• Low blood sugar (hypoglycemia), especially when used with other anti-diabetic medications like insulin or sulfonylureas.

Serious, but rare, side effects include:

• Lactic acidosis: Symptoms may include persistent nausea, vomiting, stomach pain, muscle pain or weakness, difficulty breathing, dizziness, tiredness, and a feeling of coldness in the arms and legs. Seek immediate medical attention if these occur.

Precautions

• Contraindications: Do not take if you have known hypersensitivity or allergy to vildagliptin, metformin, or any other ingredients. It is contraindicated in patients with severe kidney or liver disease, Type 1 Diabetes Mellitus, diabetic ketoacidosis, or conditions associated with metabolic acidosis. It is also not recommended for children under 18 years of age.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding. It is generally not recommended during pregnancy or breastfeeding unless deemed necessary by a healthcare professional.
• Alcohol Consumption: Avoid chronic excessive alcohol consumption as it can increase the risk of lactic acidosis.
• Kidney and Liver Disease: Use with caution in patients with kidney or liver problems; dosage adjustments or alternative medications may be required. It is contraindicated in severe cases.
• Heart Conditions: Caution is advised for patients at risk of lactic acidosis, such as those with congestive heart failure.
• Surgery: Inform your doctor if you are scheduled for surgery, as the medication may need to be discontinued temporarily.
• Driving and Operating Machines: If you experience dizziness or low blood sugar, avoid driving or operating machinery until you feel well.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are taking, as VILDAPRIDE M can interact with certain drugs, including carbonic anhydrase inhibitors, hyperglycemic medications, and ACE-inhibitors.

Storage

• Store at a temperature not exceeding 30°C.
• Protect the medicine from moisture, direct light, and heat.
• Keep out of the sight and reach of children and pets.

Here are the most frequently asked questions about VILDAPRIDE M 50/1000 MG TABLET:

What is Vildapride M 50/1000 mg Tablet used for?

Vildapride M 50/1000 mg Tablet is used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is prescribed when diet and exercise alone, or treatment with either metformin or vildagliptin alone, is not sufficient to control blood sugar. This medicine also helps reduce the risk of serious complications associated with diabetes, such as kidney damage, blindness, nerve problems, limb amputations, and cardiovascular events.

How does Vildapride M 50/1000 mg Tablet work?

Vildapride M 50/1000 mg Tablet contains two active ingredients: Vildagliptin (50 mg) and Metformin (1000 mg). Vildagliptin works by increasing the release of insulin from the pancreas in a glucose-dependent manner and reducing the production of glucagon, a hormone that raises blood sugar levels. Metformin reduces the production of glucose in the liver, decreases the absorption of glucose from the intestines, and enhances the body's sensitivity to insulin. Together, these actions provide better control of both fasting and post-meal blood sugar levels.

What is the usual dosage for Vildapride M 50/1000 mg Tablet?

The dosage of Vildapride M 50/1000 mg Tablet is determined by your doctor based on your individual condition and response to treatment. It is typically taken twice daily, with or after meals, to help reduce stomach upset. It is important to swallow the tablet whole with a glass of water and not to crush, chew, or break it. For optimal results, take it at the same time each day and do not exceed the prescribed dose or stop taking it without consulting your doctor.

What are the possible side effects of Vildapride M 50/1000 mg Tablet?

Common side effects may include headache, dizziness, nausea, vomiting, diarrhea, stomach pain, fatigue, constipation, low blood pressure, trembling of hands and feet, changes in taste, and upper respiratory tract infections. A more serious but rare side effect is lactic acidosis, which can cause symptoms like muscle pain, difficulty breathing, dizziness, persistent stomach pain, and severe tiredness. If you experience symptoms of low blood sugar (hypoglycemia) such as sweating, hunger pangs, or palpitations, especially if also taking insulin or sulfonylureas, you should know how to manage it. Long-term use may also lead to Vitamin B12 deficiency.

Is Vildapride M 50/1000 mg Tablet safe during pregnancy or breastfeeding?

Vildapride M 50/1000 mg Tablet is generally not recommended during pregnancy unless specifically advised by a doctor, as there is limited information on its safety in pregnant women, and animal studies have indicated potential harmful effects. For breastfeeding mothers, this medicine is also not recommended, as its components can pass into breast milk and may pose a risk of hypoglycemia to the baby. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can Vildapride M 50/1000 mg Tablet be taken with other medications?

Vildapride M 50/1000 mg Tablet can interact with various other medications. It is crucial to inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential interactions. Some medications that may interact include certain painkillers (e.g., ibuprofen), blood pressure medications (e.g., ACE-inhibitors), thyroid hormones, diuretics, cationic medications (e.g., digoxin), and carbonic anhydrase inhibitors. The use of iodinated contrast agents (used in some medical imaging) is generally avoided due to an increased risk of lactic acidosis.

What precautions should be taken while taking Vildapride M 50/1000 mg Tablet?

This medicine is not suitable for children under 18 years of age. Exercise caution if you are an older patient (65 years and above). Vildapride M 50/1000 mg Tablet is contraindicated in individuals with type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, certain heart conditions, or a history of metabolic acidosis. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis. Your doctor may regularly monitor your kidney and liver function. If you experience dizziness or fatigue, avoid driving or operating machinery. It is important to maintain a healthy diet and regular exercise routine while on this medication.

What happens if a dose of Vildapride M 50/1000 mg Tablet is missed?

If you miss a dose of Vildapride M 50/1000 mg Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Vildapride M 50/1000 mg Tablet be stored?

Store Vildapride M 50/1000 mg Tablet at a temperature not exceeding 30°C. Keep it in a cool, dry place, protected from direct sunlight, moisture, and heat. Always keep this medicine out of the reach of children and pets. Properly discard any unused or expired medicine; do not flush it down the toilet or throw it into the drain.