Pioz V Tab

PIOZ V Tablet

PIOZ V Tablet is a combination medication manufactured by US VITAMINS (USV) designed for the management of type 2 diabetes mellitus. It effectively controls high blood sugar levels by addressing insulin resistance and improving glycemic control.

• Name:

  • Brand Name: PIOZ V Tablet
  • Manufacturer: USV Private Limited

• Composition:

  • Each tablet contains: Pioglitazone (15 mg) and Vildagliptin (50 mg).

• Uses: PIOZ V Tablet is primarily used for:

  • Managing high blood sugar levels in adults with type 2 diabetes mellitus.
  • Improving glycemic control as an adjunct to diet and exercise.
  • Reducing blood glucose levels by enhancing insulin sensitivity.
  • Minimizing the risk of diabetes-related complications.
  • Potentially beneficial in reducing fatty liver in patients with uncontrolled diabetes.

• Dosage and Administration:

  • The daily dose should be taken as prescribed by your doctor.
  • It is typically taken orally, usually once daily, with or without food.
  • Consistency in timing is important for optimal results; try to take it at the same time each day.
  • Swallow the tablet whole; do not chew, crush, or break it.

• Side Effects:

  • Common Side Effects: Upper respiratory tract infections, headache, peripheral oedema (swelling), weight gain, nausea, diarrhea, abdominal pain, muscle pain, sore throat, runny nose, fever.
  • Most side effects are temporary and usually resolve upon discontinuing the medication.
  • Serious Side Effects: May cause or worsen heart failure, especially in patients with existing cardiac problems. Bladder cancer may rarely happen.

• Precautions:

  • PIOZ V Tablet is not advised for type 1 diabetes mellitus or diabetic ketoacidosis.
  • Not recommended for patients with severe kidney or liver impairment or a history of heart disease.
  • Caution is advised during pregnancy and breastfeeding.
  • Alcohol consumption may affect blood sugar control.
  • Inform your doctor about all other medications, as interactions can occur with CYP2C8 inhibitors/inducers, ACE inhibitors, insulin, or insulin secretagogues.
  • Regular monitoring of blood sugar levels and liver function is recommended.

• Storage:

  • Store at room temperature below 30°C (20-25°C).
  • Protect from moisture and light.
  • Keep out of reach of children.
  • Do not use after the expiry date.

PIOZ V TAB, manufactured by US VITAMINS (USV), is a combination medication containing Pioglitazone (15mg) and Vildagliptin (50mg). It is primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus.

Here are some frequently asked questions about PIOZ V TAB:

What is PIOZ V TAB used for?

PIOZ V TAB is used to treat type 2 diabetes mellitus. It helps manage high blood sugar levels by improving the body's response to insulin and increasing insulin secretion. This can reduce the risk of serious complications associated with diabetes, such as kidney damage, eye damage, nerve problems, limb loss, and heart disease. It is also approved for patients with uncontrolled diabetes who have fatty liver.

How does PIOZ V TAB work?

PIOZ V TAB contains two active ingredients: Pioglitazone and Vildagliptin. Pioglitazone belongs to the thiazolidinedione class of drugs and works by increasing the body's sensitivity to insulin, allowing cells in muscles, fat, and the liver to utilize glucose more efficiently. It also reduces glucose production by the liver. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that prevents the breakdown of incretin hormones, which helps to increase insulin secretion from the pancreas and suppress glucagon release, thereby lowering blood sugar levels after meals.

What is the usual dosage for PIOZ V TAB?

The dosage of PIOZ V TAB is determined by your doctor based on your individual needs, blood sugar levels, and response to treatment. Typically, the starting dose is one tablet daily, but this can be adjusted. It is important to follow your doctor's instructions carefully and not to change your dose without their advice. The tablet should be swallowed whole and can be taken with or without food, preferably at the same time each day for consistent benefits.

What are the possible side effects of PIOZ V TAB?

Common side effects of PIOZ V TAB are usually mild and may include upper respiratory tract infection, headache, muscle pain, sore throat, runny nose, fever, itchy rash, trembling, joint pain, constipation, edema (swelling), diarrhea, nausea, and heartburn. If these effects persist or worsen, it's advisable to consult your doctor.

Is PIOZ V TAB safe during pregnancy or breastfeeding?

PIOZ V TAB is generally not recommended during pregnancy and breastfeeding. Information regarding its use during pregnancy and breastfeeding is often not available, and pregnant or nursing women should consult their healthcare provider before commencing this medication. Your doctor can advise on safer alternative treatments.

Can PIOZ V TAB be taken with other medications?

PIOZ V TAB can interact with other medications. It is important to inform your doctor about all other medications, herbal supplements, and vitamins you are taking to avoid potential drug interactions. For example, medicines like gemfibrozil (CYP2C8 inhibitor) may increase pioglitazone concentration, while rifampin (CYP2C8 inducer) can decrease it. Taking it with insulin or other insulin secretagogues may increase the risk of low blood sugar (hypoglycemia).

What precautions should be taken while using PIOZ V TAB?

Several precautions should be taken:

• PIOZ V TAB is not suitable for individuals with type 1 diabetes mellitus, diabetic ketoacidosis, severe kidney or liver disease, or a history of heart disease, thyroid disorders, or certain hormonal conditions.
• Regular monitoring of blood sugar levels, blood cell counts, and liver function is advised.
• Maintain a healthy lifestyle, including a balanced diet, regular exercise, and weight management, as this medicine is part of a comprehensive diabetes management plan.
• Be aware of the symptoms of low blood sugar (hypoglycemia), especially if taking other diabetes medications, and know how to respond.
• If you experience dizziness or fatigue, avoid driving or operating machinery.
• Limit alcohol consumption as it may affect blood sugar levels.

What happens if a dose of PIOZ V TAB is missed?

If you miss a dose of PIOZ V TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should PIOZ V TAB be stored?

PIOZ V TAB should be stored at room temperature (below 30°C or 20-25°C), away from moisture and heat, and protected from direct sunlight. Keep it out of reach of children.