Nupenta Dsr Capsule (15 Cap)

NUPENTA DSR CAPSULE (15 CAP) by MACLEODS PHARMACEUTICALS LTD.

Name

Brand Name: NUPENTA DSR CAPSULE

Composition

NUPENTA DSR CAPSULE contains two active ingredients:

• Pantoprazole (40 mg)
• Domperidone (30 mg)

Uses

NUPENTA DSR CAPSULE is primarily used to treat conditions related to excessive stomach acid and impaired gastrointestinal motility. These include:

• Gastroesophageal Reflux Disease (GERD), also known as acid reflux
• Erosive esophagitis (inflammation of the esophagus due to acid reflux)
• Peptic ulcers (gastric and duodenal ulcers)
• Symptoms such as heartburn, indigestion, stomach pain, acidity, nausea, vomiting, upper abdominal discomfort, bloating, and regurgitation

Dosage and Administration

This medicine should be taken orally, typically once daily, 30-60 minutes before a meal, preferably in the morning. The capsule should be swallowed whole with a glass of water and not crushed, chewed, opened, or broken. The duration of treatment will be determined by a physician based on the patient's condition.

Side Effects

Common side effects include:

• Headache
• Diarrhea
• Stomach pain
• Flatulence (gas)
• Dry mouth
• Dizziness
• Nausea and vomiting

Serious side effects, though less common, warrant immediate medical attention:

• Severe allergic reactions (skin rash, itching, swelling of lips/face/body, difficulty breathing/swallowing)
• Signs of liver problems (yellowing of skin/eyes, dark urine, tiredness)
• Severe skin reactions (redness, blistering, peeling of skin, bleeding in lips/eyes/mouth/nose/genitals with fever)
• Signs of kidney problems (lower back pain, painful urination)
• Low magnesium levels (hypomagnesemia), especially with long-term use

Precautions

• Pregnancy and Breastfeeding: Not recommended during pregnancy and should be used with caution during breastfeeding. Consult a doctor.
• Alcohol: Avoid alcohol as it can increase acid production and worsen drowsiness.
• Driving and Operating Machinery: May cause dizziness and sleepiness; avoid activities requiring mental focus until the effects are known.
• Pre-existing Conditions: Inform your doctor if you have kidney, liver, or heart problems, osteoporosis, a history of fractures, a stomach tumor, C. difficile induced colitis, intestinal blockage, or prolactinoma.
• Drug Interactions: Inform your doctor about all other medications, including antifungals, antibiotics, immunosuppressants, and diuretics, to prevent potential drug interactions.
• Long-term Use: Prolonged use may increase the risk of bone fractures, low magnesium levels, and Vitamin B12 deficiency. Regular monitoring may be advised for long-term therapy.

Storage

Store in a cool and dry place, away from direct sunlight. Keep out of sight and reach of children. The medicine should be stored at room temperature, typically below 25°C or 30°C, and protected from excessive light and moisture. Do not use the medicine after its expiry date.

NUPENTA DSR CAPSULE is a combination medication containing Pantoprazole and Domperidone, used primarily to treat various gastrointestinal conditions related to acidity and digestive motility.

Here are some frequently asked questions about NUPENTA DSR CAPSULE:

What is NUPENTA DSR CAPSULE used for?

NUPENTA DSR CAPSULE is primarily used to treat gastroesophageal reflux disease (GERD), which involves the backward flow of stomach acid into the food pipe, causing symptoms like heartburn and acid reflux. It is also effective in managing peptic ulcers, acidity, indigestion (dyspepsia), gastritis (inflammation of the stomach lining), and associated symptoms like nausea, vomiting, bloating, and stomach pain.

How does NUPENTA DSR CAPSULE work?

This medicine combines two active ingredients: Pantoprazole and Domperidone. Pantoprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach. It achieves this by blocking the hydrogen-potassium ATPase enzyme system (proton pump) in the stomach lining, which is responsible for acid secretion. Domperidone is a prokinetic and anti-nausea agent that increases the movement of the stomach and intestines, helping food move more easily through the digestive tract and preventing acid buildup and reflux.

What is the usual dosage for NUPENTA DSR CAPSULE?

The dosage of NUPENTA DSR CAPSULE should always be as prescribed by your doctor, as it can vary based on your condition and response to treatment. It is typically recommended to take one capsule daily, preferably in the morning, about 30-60 minutes before a meal, on an empty stomach. The capsule should be swallowed whole with a glass of water, without crushing, chewing, or opening it.

What are the possible side effects of NUPENTA DSR CAPSULE?

While generally considered safe when prescribed, some individuals may experience mild side effects. Common side effects include headache, diarrhea, nausea, vomiting, stomach pain, flatulence (gas), and dryness of the mouth. Less common or rare side effects might include dizziness, skin rash, itching, weakness, fatigue, anxiety, and insomnia. If any side effects persist or worsen, it is important to consult your doctor. Severe allergic reactions, signs of liver or kidney problems, or signs of low magnesium levels (e.g., tiredness, irregular heartbeat) require immediate medical attention.

Is NUPENTA DSR CAPSULE safe during pregnancy or breastfeeding?

NUPENTA DSR CAPSULE is generally not recommended for use during pregnancy due to a lack of controlled studies and potential effects on the fetus. Pregnant women should consult their doctor before taking this medicine. Similarly, it is not recommended during breastfeeding as it can pass into breast milk and affect the nursing infant.

Can NUPENTA DSR CAPSULE be taken with other medications?

NUPENTA DSR CAPSULE can interact with various medications. It may reduce the effectiveness of antifungal medications like ketoconazole and fluconazole. When taken with antibiotics like erythromycin, there's an increased risk of irregular heartbeats. It can also elevate the blood concentration of immunosuppressants such as methotrexate and may interact with diuretics like furosemide, antiplatelet medicines like clopidogrel, and thyroid hormones like levothyroxine. Always inform your doctor about all medications, supplements, and herbal products you are currently taking to avoid potential drug interactions.

What precautions should be taken when using NUPENTA DSR CAPSULE?

Before taking NUPENTA DSR CAPSULE, inform your doctor if you have severe liver disease, kidney problems, heart conditions, or a history of bone fractures or osteoporosis. Prolonged use may lead to low levels of calcium and magnesium in the body, so regular monitoring and supplements might be advised. This medicine may cause dizziness and sleepiness, so caution is advised when driving or operating machinery until you know how it affects you. Alcohol consumption should be avoided as it can increase acid production and worsen sleepiness. It is contraindicated if you are allergic to pantoprazole, domperidone, or any of its ingredients, or if you have a blockage in your digestive tract.

What happens if a dose of NUPENTA DSR CAPSULE is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing pattern. Do not take a double dose to make up for a missed one.

How should NUPENTA DSR CAPSULE be stored?

NUPENTA DSR CAPSULE should be stored in a cool and dry place, away from direct sunlight and moisture, and out of the sight and reach of children. It should be stored at room temperature, typically below 25°C or 30°C.