Udiliv 450 Mg Tablet ( 10 Tab )

UDILIV 450 MG TABLET

UDILIV 450 MG TABLET, manufactured by Abbott Healthcare Pvt. Ltd., is a medication primarily used for various liver and gallbladder disorders.

• Name:

  • Brand Name: Udiliv 450 Tablet
  • Common Name: Ursodeoxycholic Acid Tablet

• Composition:

  • Each tablet contains Ursodeoxycholic Acid (UDCA) 450 mg. Ursodeoxycholic acid is a naturally occurring bile acid.

• Uses: UDILIV 450 MG TABLET is prescribed for several medical conditions, including:

  • Dissolving cholesterol-based gallstones that are not visible on X-ray and when the gallbladder is still functioning.
  • Treatment of primary biliary cholangitis (PBC), an autoimmune liver disease.
  • Management of liver dysfunction associated with cystic fibrosis in children aged 6 to 18 years.
  • Treating other cholestatic liver diseases, alcoholic fatty liver disease, and non-alcoholic fatty liver.

• Dosage and Administration:

  • The tablet should be swallowed whole with a glass of water or milk, ideally after a meal. Do not chew, crush, or break the tablet.
  • Dosage depends on the condition being treated and the patient's body weight, as determined by a doctor.
  • For dissolving gallstones, it is often recommended to take one dose daily at night. Regular intake for several months or longer may be necessary.

• Side Effects: Common side effects may include:

  • Abdominal pain or discomfort
  • Diarrhea
  • Nausea
  • Rash and itching
  • Hair loss
  • Dizziness
  • Constipation

  If diarrhea is persistent, the doctor may reduce the dose or discontinue treatment.

• Precautions:

  • Inform your doctor if you have allergies to ursodeoxycholic acid or any other ingredients.
  • Contraindicated in patients with stomach/intestinal ulcers or bleeding, recent intestinal surgery, non-functional gallbladder, bile duct obstruction/inflammation, or acute liver inflammation.
  • Use with caution in pregnant and breastfeeding women; consult a doctor.
  • Avoid alcohol consumption as it may increase drowsiness and liver damage.
  • Avoid concomitant use with certain antacids, cholesterol-lowering medicines (e.g., cholestyramine, colestipol, clofibrate, atorvastatin), antibiotics (ciprofloxacin), immunosuppressants (cyclosporine), and hormonal contraceptives as they may reduce efficacy or increase gallstone formation.
  • Liver function tests may be monitored regularly, especially during the initial months of treatment.

• Storage:

  • Store in a cool and dry place, protected from direct sunlight.
  • Keep out of sight and reach of children.
  • Store below 30°C, ideally between 10ºC and 25ºC, and do not refrigerate or freeze.

What is UDILIV 450 MG TABLET used for?

UDILIV 450 MG TABLET is primarily used to dissolve gallstones that are made of cholesterol. It is also prescribed for various liver-related disorders, including primary biliary cholangitis (PBC), primary sclerosing cholangitis, and liver dysfunction associated with cystic fibrosis.

How does UDILIV 450 MG TABLET work?

UDILIV 450 MG TABLET contains ursodeoxycholic acid (UDCA), a naturally occurring bile acid. It works by reducing the production and absorption of cholesterol in the liver and intestines, which decreases the cholesterol content in bile. This action helps to dissolve existing cholesterol gallstones and prevents the formation of new ones. UDCA also protects liver cells from damage caused by toxic bile acids and improves liver function.

What is the usual dosage for UDILIV 450 MG TABLET?

The dosage of UDILIV 450 MG TABLET depends on the condition being treated and the patient's body weight. For primary biliary cholangitis, the recommended dose is typically 13 to 15 mg/kg of body weight per day, often divided into several administrations. When used for dissolving gallstones, it may be recommended to take one dose daily at night, usually after meals with a glass of milk or water. It is crucial to follow the specific instructions provided by your doctor.

What are the possible side effects of UDILIV 450 MG TABLET?

Common side effects may include abdominal pain, diarrhea, nausea, rash, itching, hair loss, dizziness, indigestion, and weakness. Most of these side effects are temporary and usually resolve over time. If side effects persist or worsen, it is important to consult your doctor. Persistent diarrhea might lead to a dose reduction or discontinuation of the therapy.

Is UDILIV 450 MG TABLET safe during pregnancy or breastfeeding?

UDILIV 450 MG TABLET should be used during pregnancy only if clearly necessary, and the benefits outweigh the potential risks, as there are limited human studies. For breastfeeding women, caution is advised, though limited human data suggests the drug does not pose a significant risk to the baby. Women of childbearing potential should use reliable non-hormonal contraception or low-estrogen oral contraceptives, especially when taking the medicine for gallstone dissolution, as hormonal contraceptives can increase gallstone production.

Can UDILIV 450 MG TABLET be taken with other medications?

UDILIV 450 MG TABLET can interact with several medications. Cholesterol-lowering medicines like cholestyramine or colestipol, and some antacids containing aluminum hydroxide, may reduce its effectiveness, so it should be taken with at least a 2-hour gap. Hormonal birth control pills should be discontinued, as they can increase gallstone formation. Immunosuppressants like ciclosporin may have increased blood levels when taken with UDILIV 450 MG TABLET. It is important to inform your doctor about all other medications you are taking.

What precautions should be taken?

Inform your doctor if you have allergies to ursodeoxycholic acid, or conditions such as inflammation of the gallbladder or bile ducts, biliary obstruction, frequent cramp-like pain in the upper abdomen, variceal bleeding, ascites, liver encephalopathy, or a non-functional gallbladder. Regular liver function tests and ultrasound scans may be recommended to monitor your liver and gallbladder during treatment. Avoid a high-cholesterol diet as it may affect the medicine's efficacy, and limit alcohol consumption, as it can lead to increased drowsiness and liver damage.

What happens if a dose is missed?

If you miss a dose of UDILIV 450 MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to compensate for the missed one.

How should UDILIV 450 MG TABLET be stored?

UDILIV 450 MG TABLET should be stored in a cool and dry place, protected from direct heat and light, ideally below 30°C. Keep the medicine out of sight and reach of children. Do not refrigerate or freeze.