Ramihart 5 Mg Capsule (10 Cap)

RAMIHART 5 MG CAPSULE (10 CAP) by MANKIND PHARMA LTD.

Name

• Brand Name: RAMIHART 5 MG CAPSULE
• Common Name: Ramipril 5mg Capsule

Composition

RAMIHART 5 MG CAPSULE contains Ramipril as its active ingredient, at a strength of 5 mg. Ramipril belongs to a class of medicines known as Angiotensin-Converting Enzyme (ACE) inhibitors. It works by reducing the production of substances that constrict blood vessels, thus relaxing and widening them to promote smoother blood flow and reduce the heart's workload.

Uses

RAMIHART 5 MG CAPSULE is primarily prescribed for:

• Hypertension (high blood pressure): It helps lower elevated blood pressure, making it easier for the heart to pump blood.
• Heart Failure: It is used to treat and manage heart failure, improving symptoms and helping the heart function more efficiently.
• Prevention of Heart Attack and Stroke: It reduces the risk of cardiovascular events such as heart attacks and strokes, especially in high-risk patients.
• Post-Myocardial Infarction: It may be prescribed after a heart attack to reduce the risk of future cardiovascular events.
• Protection of Kidney Function: It helps protect kidney function, particularly in patients with diabetes or mild to moderate kidney disease.

Dosage and Administration

RAMIHART 5 MG CAPSULE is typically taken once daily, preferably at the same time each day to maintain consistent levels in the bloodstream. It can be taken with or without food. The capsule should be swallowed whole with a glass of water and should not be chewed, crushed, or broken. The initial dose for hypertension, heart failure, or post-myocardial infarction is often 1.25 mg or 2.5-5 mg once a day, and the dose may be gradually increased up to a maximum of 10 mg per day as needed, under medical supervision.

Side Effects

Common Side Effects

• Headache
• Dizziness, lightheadedness, or feeling tired
• Dry, persistent cough
• Nausea, vomiting, or diarrhea
• Fatigue or weakness
• Skin rash
• Increased blood potassium levels (hyperkalemia)

Serious Side Effects (Seek immediate medical attention if you experience)

• Angioedema (sudden swelling of the face, lips, tongue, throat, arms, or legs, with difficulty breathing or swallowing).
• Symptoms of liver problems such as yellowing of skin or eyes (jaundice), right upper belly pain, dark urine.
• Signs of kidney injury such as a decrease in urine amount, swelling of ankles, hands, or feet.
• Very low blood pressure causing fainting or severe dizziness.
• High potassium levels with symptoms like muscle weakness, chest pain, or irregular heartbeats.

Precautions

• Pregnancy and Breastfeeding: RAMIHART 5 MG CAPSULE is not recommended during pregnancy as it may harm the baby. It is also not advisable during breastfeeding due to limited data and potential risks to the infant.
• Allergies: Do not take this medicine if you are allergic to ramipril or any other ACE inhibitors.
• Kidney and Liver Conditions: Use with caution in patients with kidney disease (especially renal artery stenosis or those on dialysis) or liver disease; dose adjustments and monitoring may be necessary.
• Other Medical Conditions: Caution is advised for patients with heart conditions, collagen vascular diseases, diabetes, or those with low blood pressure or dehydration.
• Drug Interactions: Inform your doctor about all medications, supplements, and herbal products you are taking. Interactions can occur with other blood pressure medications, diuretics, potassium supplements, NSAIDs (like ibuprofen), and anti-diabetic medicines. Concomitant use with sacubitril/valsartan is contraindicated within 36 hours.
• Alcohol: Avoid excessive alcohol consumption as it can enhance side effects like dizziness and lightheadedness.
• Driving and Operating Machinery: This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you.
• Potassium-Rich Foods: Avoid excessive intake of potassium-rich foods, as Ramipril can affect potassium levels.

Storage

Store RAMIHART 5 MG CAPSULE in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep it out of sight and reach of children. Always check the expiry date.

What is RAMIHART 5 MG CAPSULE used for?

RAMIHART 5 MG CAPSULE is primarily used to treat high blood pressure (hypertension). It also helps to prevent heart attacks, strokes, and heart failure, and is prescribed after a heart attack to improve outcomes. Additionally, it helps protect kidney function, particularly in individuals with diabetes or mild-to-moderate kidney diseases.

How does RAMIHART 5 MG CAPSULE work?

RAMIHART 5 MG CAPSULE contains Ramipril, which is an Angiotensin-Converting Enzyme (ACE) inhibitor. It works by blocking the formation of a substance in the body called angiotensin II, which normally constricts blood vessels. By inhibiting this, Ramipril relaxes and widens the blood vessels, making it easier for the heart to pump blood and thereby lowering blood pressure.

What is the usual dosage of RAMIHART 5 MG CAPSULE?

The usual dosage is typically once a day. The starting dose is often 2.5 mg, which may be gradually increased by your doctor up to a maximum of 10 mg once daily. For certain conditions like heart failure or after a heart attack, a dose of 5 mg twice a day or 10 mg once a day might be prescribed. The capsule should be swallowed whole with water and can be taken with or without food, preferably at the same time each day.

What are the possible side effects of RAMIHART 5 MG CAPSULE?

Common side effects may include headache, dizziness, fatigue, and a persistent dry cough. Other possible side effects are nausea, diarrhea, and rash. It can also increase blood potassium levels. More serious, but rare, side effects like angioedema (swelling of the face, lips, or tongue) can occur, which require immediate medical attention.

Is RAMIHART 5 MG CAPSULE safe during pregnancy or breastfeeding?

No, RAMIHART 5 MG CAPSULE is not recommended during pregnancy, especially in the second and third trimesters, as it can cause serious harm or even death to the unborn baby. It is also not advised during breastfeeding due to potential harmful effects on the nursing baby. If you are pregnant, planning to conceive, or breastfeeding, consult your doctor for alternative medications.

Can RAMIHART 5 MG CAPSULE be taken with other medications?

RAMIHART 5 MG CAPSULE can interact with other medications. Caution is advised when taken with diuretics (water pills), potassium supplements, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), anti-diabetic medicines, medications containing aliskiren (for diabetes or kidney disease), and sacubitril/valsartan (for heart failure). Always inform your doctor about all prescription, over-the-counter medicines, herbal preparations, and supplements you are taking to avoid potential interactions.

What precautions should be taken while using RAMIHART 5 MG CAPSULE?

It is important to inform your doctor about any history of allergies, heart, kidney, or liver problems before starting this medication. Regular monitoring of your blood pressure, electrolyte levels (especially potassium), and kidney function is recommended during treatment. Avoid consuming alcohol as it can enhance the blood pressure-lowering effect and cause excessive dizziness. Do not use salt substitutes or potassium supplements unless advised by your doctor, as Ramipril can increase potassium levels. This medicine may cause dizziness, so avoid driving or operating heavy machinery if you feel dizzy. It is not recommended for children below 18 years of age. Do not stop taking RAMIHART 5 MG CAPSULE suddenly without consulting your doctor, as this can lead to a sudden increase in blood pressure.

What happens if a dose of RAMIHART 5 MG CAPSULE is missed?

If you miss a dose of RAMIHART 5 MG CAPSULE, simply skip the missed dose and continue with your regular dosing schedule at the usual time. Do not take a double dose to make up for the forgotten one.

How should RAMIHART 5 MG CAPSULE be stored?

RAMIHART 5 MG CAPSULE should be stored in a cool and dry place, away from direct sunlight and moisture. The ideal storage temperature is below 30°C. Keep it out of the sight and reach of children.