Clonil 10 Tablet

CLONIL 10 Tablet

CLONIL 10 Tablet is a medication manufactured by Intas Pharmaceuticals Ltd..

• Name:

  • Brand Name: CLONIL 10 Tablet
  • Common Name: Clomipramine (10mg)

• Composition: CLONIL 10 Tablet contains 10mg of Clomipramine as its active ingredient. Clomipramine is classified as a tricyclic antidepressant (TCA). It works by increasing the levels of certain chemical messengers in the brain, specifically serotonin and noradrenaline, which play crucial roles in regulating mood, behavior, and emotions.

• Uses: CLONIL 10 Tablet is prescribed for adults to treat a range of psychological conditions, including:

  • Obsessive-Compulsive Disorder (OCD), characterized by obsessive thoughts and compulsive behaviors.
  • Depression, particularly when sedation is helpful or when it is unresponsive to other treatments.
  • Phobic states and panic disorder, which involve intense and persistent fears or sudden feelings of unnecessary fear.
  • Muscular weakness (cataplexy) associated with narcolepsy, a sleep disorder causing uncontrollable daytime sleepiness.

• Dosage and Administration: CLONIL 10 Tablet should be taken exactly as prescribed by a doctor. The dose is typically started low and increased gradually to minimize side effects. It is recommended to take the medicine at the same time every day for optimal effectiveness and to avoid missing doses. It can be taken with or without food, but taking it with food may reduce gastrointestinal side effects. The tablet should be swallowed whole and not be chewed, crushed, or broken. Do not stop the medication suddenly, even if symptoms improve, as abrupt cessation can lead to withdrawal symptoms.

• Side Effects:

  • Common Side Effects: Dry mouth, constipation, dizziness, drowsiness, blurred vision, increased sweating, changes in appetite or weight (including weight gain), nausea, indigestion, tremors, nervousness, altered libido, ejaculation disorder, impotence, micturition disorders, and fatigue. These are often mild and may improve as the body adjusts to the medicine.
  • Serious Side Effects: Seizures, heart rhythm problems, increased suicidal thoughts in young people (especially early in treatment), severe heartbeat changes, fainting, chest pain, and signs of serotonin syndrome (such as high fever, stiff muscles, or confusion). Other serious concerns include delirium, hallucinations, confusion, or mania. Immediate medical attention is necessary if any serious side effects occur.

• Precautions:

  • Contraindications/Warnings: CLONIL 10 Tablet should not be used with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of stopping them due to the risk of life-threatening serotonin syndrome.
  • Alcohol: Avoid consuming alcohol as it can worsen drowsiness and other side effects.
  • Pregnancy and Breastfeeding: It may be unsafe to use during pregnancy and is probably unsafe during breastfeeding; consult a doctor.
  • Driving and Operating Machinery: Avoid driving or operating heavy machinery if experiencing dizziness, drowsiness, blurred vision, or difficulty concentrating.
  • Medical Conditions: Use with caution in individuals with heart disease, seizure disorders, glaucoma, difficulty passing urine, liver disease, kidney disease, or a history of low blood pressure.
  • Suicidal Thoughts: Close monitoring for suicidal thoughts is important, especially at the beginning of treatment, particularly in young adults.
  • Drug Interactions: Inform your doctor about all other medications, including over-the-counter drugs and supplements, as interactions can occur with medications like antifungals, antacids, Parkinson's disease medications, anti-malarial medication, barbiturates, medicines for urine incontinence, bronchodilators, antihistamines, and cough medicine.
  • Food Interactions: Avoid consuming grapefruit or grapefruit juice as it may increase the level of the medication in your blood.
  • Age: Not recommended for children below 17 years of age. Use with caution in elderly patients due to an increased risk of low sodium levels.

• Storage: Keep CLONIL 10 Tablet out of the sight and reach of children. Store in a cool and dry place, protected from light and moisture. Regularly check the expiration date and dispose of unused or expired medication properly.

CLONIL 10 TABLET by INTAS PHARMACEUTICALS LTD is a medication primarily used to treat various mental health conditions. Here are some frequently asked questions about this medicine.

What is CLONIL 10 TABLET used for?

CLONIL 10 TABLET is a tricyclic antidepressant primarily used in adults to treat obsessive-compulsive disorder (OCD), phobic states, and depression, especially when sedation is beneficial. It can also be used to manage panic disorder, anxiety disorder, and muscular weakness (cataplexy) associated with narcolepsy.

How does CLONIL 10 TABLET work?

CLONIL 10 TABLET contains Clomipramine, which is a tricyclic antidepressant. It works by increasing the levels of certain natural chemical messengers in the brain, namely serotonin and noradrenaline (norepinephrine). This action helps to regulate mood, thoughts, and behavior, thereby reducing obsessive thoughts, lessening compulsive behaviors, easing anxiety from phobias, and improving mood in depression.

What is the usual dosage for CLONIL 10 TABLET?

The dosage of CLONIL 10 TABLET is determined by your doctor and is typically started low, then gradually increased to minimize side effects. It should be taken exactly as prescribed, usually once or twice daily, with or without food. Taking it at the same time each day is recommended for best results, and it may be advised to take it before bedtime due to its potential to cause drowsiness.

What are the possible side effects of CLONIL 10 TABLET?

Common side effects include dry mouth, constipation, dizziness, drowsiness, blurred vision, increased sweating, changes in appetite (which may lead to weight gain), nausea, indigestion, and tremors. More serious, but rare, side effects can include seizures, heart rhythm problems, and an increased risk of suicidal thoughts, especially in young people at the start of treatment. If any side effects persist or worsen, you should inform your doctor promptly.

Is CLONIL 10 TABLET safe during pregnancy or breastfeeding?

CLONIL 10 TABLET is generally not recommended during pregnancy as it may be unsafe and could cause harm to the unborn baby. It is also probably unsafe to use during breastfeeding, as the medication can pass into breast milk and potentially affect the infant, possibly causing drowsiness or feeding difficulties. It is crucial to consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can CLONIL 10 TABLET be taken with other medications?

CLONIL 10 TABLET can interact with several other medications. It should not be taken with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of stopping them, as this can lead to a serious and potentially life-threatening condition called serotonin syndrome. Interactions can also occur with other antidepressants, antiepileptics, certain heart medications, and alcohol, which should be avoided as it can worsen drowsiness and other side effects. Always inform your doctor about all medications, vitamins, and supplements you are currently taking.

What precautions should be taken while using CLONIL 10 TABLET?

Avoid consuming alcohol, as it can increase drowsiness and other side effects. Do not drive or operate heavy machinery if you experience dizziness, drowsiness, blurred vision, or difficulty concentrating. Do not stop taking the medicine suddenly without consulting your doctor, as abrupt discontinuation can lead to withdrawal symptoms. Use with caution if you have heart disease, seizure disorders, glaucoma, liver or kidney problems, or difficulty passing urine. Close monitoring for suicidal thoughts, especially in young adults, is important at the start of treatment.

What happens if a dose of CLONIL 10 TABLET is missed?

If you miss a dose of CLONIL 10 TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should CLONIL 10 TABLET be stored?

CLONIL 10 TABLET should be stored below 25°C, in a cool and dry place, protected from light and moisture. It is important to keep this medication out of the sight and reach of children.