Fabulas 40

FABULAS 40 by INTAS PHARMACEUTICALS LTD

• Name:

  • Brand Name: Fabulas 40 Tablet
  • Common Name (Active Ingredient): Febuxostat

• Composition:

  • Each tablet contains Febuxostat 40 mg. Fabulas 40 belongs to a class of medications known as xanthine oxidase inhibitors.

• Uses: Fabulas 40 is primarily used to treat and prevent gout, a chronic condition caused by high levels of uric acid in the body that can lead to crystal formation in joints, causing pain and swelling. Its uses include:

  • Managing chronic gout and hyperuricemia (excess uric acid in the blood) in adults.
  • Preventing severe gout attacks or flares.
  • Supporting patients with chronic kidney disease by managing uric acid levels, which can help protect kidney function.
  • Serving as an alternative treatment when other common gout medications, such as allopurinol, are not tolerated or fail to control uric acid levels adequately. It is not recommended for treating asymptomatic hyperuricemia.

• Dosage and Administration: Fabulas 40 Tablet is typically taken orally once daily, with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with water and should not be crushed, broken, or chewed. For optimal results, it should be taken at the same time each day. The dosage is determined by the patient's medical condition and response to treatment. It is crucial to continue taking the medication regularly, even during symptom-free periods, and not to stop it abruptly without consulting a doctor, as this could worsen the condition.

• Side Effects:

  • Common Side Effects: Nausea, rash, dizziness, diarrhoea, joint pain, musculoskeletal pain, headache, localized swelling due to fluid retention (oedema), and increased liver enzyme levels. Patients may experience an initial increase in gout attacks or flares when starting treatment.
  • Serious Side Effects: Less commonly, Fabulas 40 may cause heart problems (such as chest pain, shortness of breath, dizziness, fainting, or irregular heartbeat), liver problems (indicated by persistent nausea, dark urine, or jaundice), severe skin and allergic reactions, and changes in kidney function (including blood in urine, frequent urination, kidney stones, or abnormal urine tests).

• Precautions:

  • Inform your doctor if you have allergies to any of its components.
  • Use with caution in patients with pre-existing heart conditions, as it may increase the risk of cardiovascular events like heart attack.
  • Caution is advised for patients with kidney or liver impairment, and regular monitoring of liver and kidney function may be necessary.
  • Not recommended for use in pregnant or breastfeeding women without consulting a doctor.
  • The safety and efficacy have not been established in children under 18 years of age.
  • Alcohol consumption should be limited or avoided as it may affect the medication's effectiveness and potentially worsen gout.
  • Fabulas 40 may cause dizziness, drowsiness, blurred vision, or a tingling sensation; therefore, caution is advised when driving or operating heavy machinery.
  • Inform your doctor about all other medications, supplements, or herbal products you are taking, especially anticancer medicines (mercaptopurine), immunosuppressants (azathioprine), asthma medicine (theophylline), certain antidiabetics (rosiglitazone, pioglitazone), and anticoagulants (warfarin), as interactions may occur.
  • Patients with Lesch-Nyhan syndrome should use this medicine with caution.
  • Maintain adequate fluid intake (2-3 litres daily) while on this medication.

• Storage: Store Fabulas 40 Tablet in a cool and dry place, protected from sunlight, at temperatures between 10ºC to 25ºC or below 30ºC. Keep it out of sight and reach of children.

FABULAS 40 by INTAS PHARMACEUTICALS LTD is a medication primarily used for the management of chronic gout and hyperuricemia (high uric acid levels in the blood). It works by reducing the production of uric acid in the body, thereby preventing the formation of urate crystals that cause painful joint inflammation.

What is FABULAS 40 used for?

FABULAS 40 Tablet is used to treat and prevent gout, a type of arthritis characterized by painful joint inflammation due to high uric acid levels. It is also prescribed for managing hyperuricemia in adults with gout, especially when other common gout medications like allopurinol are not tolerated or are ineffective in controlling uric acid levels.

How does FABULAS 40 work?

FABULAS 40 contains Febuxostat, which is a xanthine oxidase inhibitor. It works by blocking the action of an enzyme called xanthine oxidase, which plays a crucial role in the production of uric acid in the body. By inhibiting this enzyme, Febuxostat effectively reduces the production of uric acid, thereby lowering blood uric acid levels and preventing the accumulation of urate crystals in the joints.

What is the usual dosage of FABULAS 40?

The usual recommended dosage for adults with gout is 40mg once daily. It can be taken with or without food, preferably at the same time each day to maintain consistent levels in the body. It is important to follow the dosage as directed by your doctor and not to increase it without consultation.

What are the possible side effects of FABULAS 40?

Common side effects of FABULAS 40 include headache, nausea, diarrhea, skin rashes, abnormal liver function, and muscle pain. Some individuals may experience an increase in gout attacks during the initial months of treatment. More serious but rare side effects can include severe allergic reactions, liver problems, heart problems, and cardiovascular events. If you experience any severe or persistent side effects, you should consult your doctor.

Is FABULAS 40 safe during pregnancy or breastfeeding?

FABULAS 40 is generally not recommended during pregnancy unless clearly necessary and only upon a doctor's recommendation, as it may be unsafe and could produce harmful effects on the fetus. Similarly, its use during breastfeeding is not recommended unless necessary, and limited data suggests it may pass into breast milk. Always consult your doctor if you are pregnant or breastfeeding.

Can FABULAS 40 be taken with other medications?

FABULAS 40 can interact with certain medications. For example, it can enhance the effects of medications like azathioprine and mercaptopurine, potentially leading to increased toxicity. It may also interact with antidiabetic medications and anticoagulants like warfarin, requiring careful monitoring and possible dose adjustments. Always inform your doctor about all current medications, supplements, and herbal products you are taking to avoid undesired effects.

What precautions should be taken while taking FABULAS 40?

Caution should be exercised if you have heart, liver, or kidney problems, as FABULAS 40 may worsen these conditions or accumulate in the body. It is not recommended for use if you are allergic to it. Initial treatment may cause a temporary increase in gout attacks, and your doctor might recommend additional treatment to manage these flares. FABULAS 40 may cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. Patients with thyroid disorders should use it with caution.

What happens if a dose of FABULAS 40 is missed?

If you miss a dose of FABULAS 40, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.

How should FABULAS 40 be stored?

FABULAS 40 should be stored in a cool and dry place, protected from light, heat, and moisture. It should be kept out of sight and reach of children. Typically, it is stored at room temperature, below 25°C or 30°C.