Esiflo 250 Mcg Transhaler

ESIFLO 250 MCG TRANSHALER by LUPIN LTD.

ESIFLO 250 MCG TRANSHALER is a combination medication designed to manage and control chronic respiratory conditions. It is manufactured by Lupin Ltd.

Composition Each actuation of ESIFLO 250 TRANSHALER contains:

• Salmeterol: 25 mcg (a long-acting beta2-adrenergic receptor agonist)
• Fluticasone Propionate: 250 mcg (a synthetic corticosteroid)

Uses ESIFLO 250 TRANSHALER is prescribed for the long-term management and prevention of symptoms associated with:

• Asthma: To maintain long-term control of asthma symptoms and prevent attacks.
• Chronic Obstructive Pulmonary Disease (COPD): Including conditions like chronic bronchitis and emphysema, by managing airflow obstruction and reducing the risk of severe flare-ups or exacerbations. This medication works by relaxing the muscles in the airways and widening them (Salmeterol) and by reducing inflammation in the lungs (Fluticasone Propionate), thereby making breathing easier.

Dosage and Administration ESIFLO 250 TRANSHALER should be administered as directed by a healthcare professional.

• Typically, the recommended dosage is two inhalations, once or twice daily.
• Shake the inhaler well for about 5 seconds before each use.
• Administer two inhalations, breathing in slowly through your mouth while pressing the inhaler, and hold your breath for approximately 10 seconds.
• After using the inhaler, it is crucial to rinse your mouth thoroughly with water and spit it out to help prevent oral candidiasis (oral thrush).
• This medicine is not intended to relieve sudden asthma attacks; a short-acting inhaler should be used for immediate relief.

Side Effects Common side effects may include:

• Nasopharyngitis (inflammation of the throat and nasal passages)
• Oral candidiasis (fungal infection in the mouth/oral thrush)
• Headache
• Nausea and vomiting
• Upper respiratory tract infection
• Cough, sore throat, or hoarse voice
• Muscle cramps, musculoskeletal (bone, muscle, or joint) pain
• Increased heart rate

Serious side effects are rare but may include severe allergic reactions (e.g., sudden wheezing, rash, swelling of the face/throat) and pneumonia.

Precautions

• Allergies: Do not use if you are allergic to fluticasone, salmeterol, milk proteins, or any other ingredients of the transhaler.
• Pregnancy and Breastfeeding: Use with caution and only if considered necessary by a physician, as the active ingredients may pass into breast milk.
• Medical Conditions: Inform your doctor if you have heart problems (e.g., coronary insufficiency, arrhythmias, high blood pressure), diabetes, liver or kidney health issues, osteoporosis, glaucoma, cataracts, thyroid disorders, low blood potassium levels (hypokalemia), seizure disorders, or active infections, as caution is advised.
• Drug Interactions: Exercise caution when co-administering with strong CYP3A4 inhibitors (e.g., ritonavir, ketoconazole), beta-blockers (e.g., atenolol, propranolol), and non-potassium-sparing diuretics.
• Prevention of Oral Thrush: Always rinse your mouth with water and spit it out after each use.

Storage Store ESIFLO 250 TRANSHALER at room temperature, ideally below 30°C. Keep it away from heat and direct light, and out of the reach of children and pets. Do not freeze.

ESIFLO 250 MCG TRANSHALER by LUPIN LTD.

What is ESIFLO 250 Transhaler used for?

ESIFLO 250 Transhaler is used for the long-term management and prevention of symptoms associated with asthma and Chronic Obstructive Pulmonary Disease (COPD). This includes conditions like chronic bronchitis and emphysema. It helps to relieve symptoms such as wheezing, shortness of breath, chest tightness, and coughing, and reduces the risk of severe flare-ups.

How does ESIFLO 250 Transhaler work?

ESIFLO 250 Transhaler is a combination of two active ingredients: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator that works by relaxing the muscles in the airways, thereby widening them and making breathing easier. Fluticasone Propionate is a corticosteroid that reduces inflammation (swelling) in the airways by stopping the release of certain chemical messengers that cause inflammatory reactions. Together, these components improve lung function and help manage respiratory symptoms.

What is the usual dosage for ESIFLO 250 Transhaler?

ESIFLO 250 Transhaler should be used exactly as prescribed by your doctor. It is typically inhaled orally, usually twice daily (in the morning and evening, 12 hours apart). Your doctor will determine the dosage based on the severity of your condition and your response to the medicine. It's important to use it around the same time each day for consistent levels of medicine in the body.

What are the possible side effects of ESIFLO 250 Transhaler?

Common side effects can include cough, upper respiratory tract infection, nasopharyngitis (inflammation of the throat and nasal passages), sinus inflammation, stomach discomfort, headache, hoarseness of voice, sore throat, and fungal infection of the oropharynx (oral candidiasis). Other reported side effects include nausea, vomiting, dizziness, muscle cramps, joint pain, and increased heart rate. Rinsing your mouth with water and spitting it out after each use can help prevent fungal infections in the mouth and throat.

Is ESIFLO 250 Transhaler safe during pregnancy or breastfeeding?

ESIFLO 250 Transhaler may be unsafe to use during pregnancy, as animal studies have shown harmful effects on the developing baby, though human studies are limited. It is advised to exercise caution and consult your doctor to weigh the benefits and risks if you are pregnant or planning a pregnancy. For breastfeeding mothers, information regarding its use is not readily available, and it's unknown if the active ingredients pass into breast milk. Caution is advised, and consultation with your doctor is recommended to discuss potential risks and benefits for the infant.

Can ESIFLO 250 Transhaler be taken with other medications?

ESIFLO 250 Transhaler can interact with certain medications. It's important to inform your doctor about all medicines, supplements, and vitamins you are taking. Potential interactions include:

• Strong CYP3A4 inhibitors: Medicines like ritonavir and ketoconazole may increase the effects of fluticasone, leading to increased side effects.
• Beta-blockers: Medicines such as atenolol or propranolol may reduce the bronchodilating effects of salmeterol and cause difficulty breathing.
• Diuretics: Non-potassium-sparing diuretics (e.g., furosemide, hydrochlorothiazide) may worsen the decrease in blood potassium levels caused by salmeterol.
• Other bronchodilators (e.g., vilanterol, formoterol, albuterol) and certain antihypertensive medications (e.g., metoprolol).

What precautions should be taken when using ESIFLO 250 Transhaler?

Always use the transhaler correctly and as advised by your doctor. Rinse your mouth with water and spit it out after each use to help prevent fungal infections (oral thrush) in the mouth and throat. Inform your doctor if you have pre-existing conditions such as heart problems (e.g., coronary insufficiency, cardiac arrhythmias, high blood pressure), diabetes, liver disease, thyroid problems (e.g., hyperthyroidism), hypokalemia (low blood potassium), glaucoma, cataracts, osteoporosis, seizure disorders, or any active infections (fungal, bacterial, or viral). Do not stop using the medicine without consulting your doctor, even if your symptoms improve, as abrupt discontinuation can lead to worsening symptoms.

What happens if a dose is missed?

If you miss a dose of ESIFLO 250 Transhaler, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take an extra dose to make up for the missed one.

How should ESIFLO 250 Transhaler be stored?

ESIFLO 250 Transhaler should be stored at room temperature, away from heat, direct light, and moisture. Keep it out of the reach of children and pets. Do not puncture the canister or expose it to high heat.