ESIFLO 250 MCG TRANSCAP (30 CAP) by LUPIN LTD.

ESIFLO 250 Transcaps is an inhalation medication prescribed for the management and prevention of respiratory conditions such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is manufactured by Lupin Ltd..

Composition

ESIFLO 250 Transcaps contains a combination of two active ingredients:

• Salmeterol (50 mcg): A long-acting bronchodilator that works by relaxing the muscles in the airways, thereby widening them and making breathing easier.
• Fluticasone Propionate (250 mcg): A corticosteroid that reduces inflammation and swelling in the airways by stopping the release of certain chemical messengers that cause inflammation.

Uses

ESIFLO 250 Transcaps is primarily used for the treatment and prevention of:

• Asthma: A chronic respiratory condition characterized by inflamed and constricted airways, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. It helps prevent asthma attacks and allows for easier breathing during daily activities.
• Chronic Obstructive Pulmonary Disease (COPD): This includes conditions like chronic bronchitis and emphysema, where there is persistent lung inflammation and obstructed airflow. The medication helps keep the airways open, relieving symptoms such as chest tightness, shortness of breath, wheezing, and coughing.

Dosage and Administration

ESIFLO 250 Transcaps should be used regularly as prescribed by your doctor. It is for inhalation use only and should not be swallowed. The medicine's full effect may be noticeable after a few days, reaching its maximum after a few weeks. It is crucial to continue using it even if symptoms improve, as discontinuing early can worsen your condition. It is not intended to relieve sudden asthma attacks; a quick-relief inhaler should be used for such instances. After each inhalation, gargling with warm water and spitting it out is advised to prevent fungal infections in the mouth and throat.

Side Effects

Common side effects may include:

• Cough
• Upper respiratory tract infection
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Headache
• Fungal infection of the oropharynx (oral thrush)
• Voice changes or hoarseness
• Throat irritation
• Stomach discomfort, nausea, or vomiting
• Muscle aches and joint pain
• Increased heart rate

Serious side effects, though rare, warrant immediate medical attention and may include severe allergic reactions (wheezing, coughing, skin rash, swelling of face/throat, rapid heartbeat, dizziness) or signs of pneumonia (fever, increased cough, breathing difficulties, changes in mucus color).

Precautions

• Medical History: Inform your doctor about any existing lung infections, liver or heart problems, diabetes, hypertension, seizures, hyperthyroidism, osteoporosis, adrenal gland problems, or a compromised immune system.
• Blood Sugar and Potassium: This medicine may increase blood sugar levels, requiring careful monitoring for diabetic patients. It may also lower blood potassium levels (hypokalemia), so caution is advised, especially for those with existing low potassium.
• Infections: Use with caution in patients with infections or tuberculosis, as corticosteroids can suppress the immune system and increase the risk of secondary infections.
• Pregnancy and Breastfeeding: Consult your doctor before using if pregnant, planning a pregnancy, or breastfeeding, as potential benefits and risks need to be evaluated.
• Alcohol: It is advisable to avoid alcohol consumption as it may increase the risk of side effects.
• Driving: If you experience drowsiness or irregular heartbeats, avoid driving or operating machinery.
• Children: Not recommended for children below 12 years of age due to insufficient safety and efficacy data.

Storage

Store below 30°C in a cool and dry place. Keep out of sight and reach of children and pets. Protect from direct sunlight, moisture, and heat.

ESIFLO 250 MCG TRANSCAP: Frequently Asked Questions

What is Esiflo 250 mcg Transcap used for?

Esiflo 250 Transcap is primarily used to treat and prevent symptoms associated with chronic obstructive pulmonary disease (COPD) and asthma. These conditions include bronchitis and emphysema. It helps manage symptoms such as wheezing, shortness of breath, chest tightness, and coughing, improving overall breathing and quality of life.

How does Esiflo 250 mcg Transcap work?

Esiflo 250 Transcap is a combination of two active ingredients: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator that works by relaxing and widening the muscles in the airways, making it easier for air to flow in and out of the lungs. Fluticasone Propionate is a corticosteroid that reduces inflammation (swelling) in the airways by blocking the release of certain chemical messengers that cause inflammation. Together, these actions help to make breathing easier.

What is the usual dosage for Esiflo 250 mcg Transcap?

The typical dosage for Esiflo 250 Transcap is usually one inhalation twice daily, as advised by your doctor. It is crucial to use it regularly at around the same time each day to ensure maximum effectiveness, and not to exceed the recommended dose. This medication is intended for inhalation only and should not be swallowed.

What are the possible side effects of Esiflo 250 mcg Transcap?

Common side effects can include headaches, throat irritation, cold symptoms, oral fungal infections (thrush) or sores, hoarseness of voice, muscle aches, and joint pain. Other potential side effects may involve coughing, upper respiratory tract infections, nasal inflammation, sinus issues, stomach discomfort, nausea, vomiting, and an increased heart rate. If any side effects persist or worsen, it's important to consult your doctor.

Is Esiflo 250 mcg Transcap safe during pregnancy or breastfeeding?

Esiflo 250 Transcap should only be used during pregnancy or while breastfeeding if explicitly prescribed by a healthcare professional, who will weigh the potential benefits against the risks. Limited studies in humans are available for pregnancy, and information regarding its use during breastfeeding is not readily available.

Can Esiflo 250 mcg Transcap be taken with other medications?

It is important to inform your doctor about all ongoing medications and herbal supplements you are taking. Caution is advised with concomitant use of certain blood pressure-lowering medicines (e.g., propranolol, atenolol), as well as medicines for fungal (e.g., ketoconazole, itraconazole), bacterial (e.g., erythromycin), and antiviral infections (e.g., ritonavir). These may increase the risk of side effects.

What precautions should be taken when using Esiflo 250 mcg Transcap?

Do not stop using this medication without consulting your doctor, even if your symptoms improve. It is not meant for sudden asthma attacks; use a quick-relief (rescue) inhaler for acute breathing difficulties. Inform your doctor if you have a history of heart, liver, kidney problems, diabetes, high cortisol levels, eye issues (like cataracts or glaucoma), seizures, weak bones (osteoporosis), thyroid disorders, or any active infections (including tuberculosis). After each inhalation, rinse your mouth with water and spit it out to help prevent oral fungal infections.

What happens if a dose of Esiflo 250 mcg Transcap is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Esiflo 250 mcg Transcap be stored?

Esiflo 250 Transcap should be stored in a cool and dry place, typically below 30°C. It should be protected from direct sunlight, moisture, and heat, and kept out of the reach of children and pets.