Inapure 5 Mg Tablet (10 Tab)

INAPURE 5 MG TABLET

INAPURE 5 MG TABLET, manufactured by SUN PHARMA LABORATORIES LTD., is a cardiac medication primarily used to manage specific heart conditions.

Composition

• Active Ingredients: Ivabradine 5 mg.

Uses INAPURE 5 MG TABLET is prescribed for:

• Angina Pectoris (Chest Pain): It is used for the symptomatic treatment of chronic stable angina in adults, especially when beta-blockers are contraindicated or not tolerated, or in combination with beta-blockers if the condition is not adequately controlled. It works by slowing the heart rate, reducing the heart's oxygen demand, and improving blood flow to the heart muscle, thereby alleviating chest pain and improving exercise tolerance.
• Chronic Heart Failure: It is used to treat chronic heart failure in adults, particularly those with a heart rate of 75 beats per minute or higher, to reduce the risk of hospitalization for worsening heart failure. The medication helps the heart pump more efficiently by slowing the heart rate, reducing strain, and improving blood circulation.

Dosage and Administration

• Adults: The typical starting dosage is 5 mg twice daily with meals (morning and evening). Depending on the patient's response and tolerability, the dose may be adjusted after 3-4 weeks to 2.5 mg, 5 mg, or 7.5 mg twice daily. The maximum recommended dose is 7.5 mg twice daily.
• Administration: Tablets should be swallowed whole with a glass of water, with food, and preferably at the same time each day. Do not crush, break, or chew the tablet.
• Children and Adolescents: Use in children and adolescents is limited and only under strict medical supervision, with dosage determined by weight and specific heart condition.

Side Effects Common side effects include:

• Slow heart rate (bradycardia)
• Luminous phenomena (temporary enhanced brightness or flashes in vision)
• Headache
• Dizziness
• Blurred vision
• High blood pressure
• Nausea
• Abdominal pain
• Diarrhea
• Atrial fibrillation (irregular or rapid heartbeat)
• ECG changes

Serious side effects may include significant changes to heart rhythm requiring urgent medical attention.

Precautions

• Contraindications: Do not take if allergic to ivabradine, or if you have severe liver disease, very low blood pressure, or heart failure that has recently worsened.
• Pregnancy and Breastfeeding: INAPURE 5 MG TABLET is highly unsafe during pregnancy and is not recommended for breastfeeding women.
• Drug Interactions: Inform your doctor about all medications, supplements, and herbal products you are taking. It should not be used with certain antifungal medicines (e.g., ketoconazole), antibiotics (e.g., clarithromycin), HIV medications (e.g., ritonavir), or some psychiatric and heart medicines (e.g., diltiazem, verapamil).
• Driving and Operating Machinery: May cause dizziness, sleepiness, or temporary vision changes. Avoid driving or activities requiring concentration until you know how it affects you.
• Underlying Conditions: Use with caution in patients with severe kidney disease or liver disease. Monitor blood pressure and heart rate regularly.
• Alcohol: It is advisable to avoid alcohol as it may enhance some side effects.

Storage Store in a cool and dry place away from sunlight, typically at room temperature (below 25°C or 30°C). Keep out of sight and reach of children.

INAPURE 5 MG TABLET (10 TAB) is a medication containing Ivabradine, primarily used to manage certain heart conditions. Below are some frequently asked questions about this medicine.

What is INAPURE 5 MG TABLET used for?

INAPURE 5 MG TABLET is prescribed for the treatment of chronic stable angina (a type of chest pain caused by reduced blood flow to the heart) and chronic heart failure (a condition where the heart cannot pump enough blood to the body). It helps to manage symptoms and reduce the risk of hospitalization for heart failure patients.

How does INAPURE 5 MG TABLET work?

This medicine contains Ivabradine, which works by selectively lowering the heart rate. It specifically targets and inhibits the "pacemaker" (If) current in the heart's sinoatrial (SA) node, which controls the heart's rhythm. By slowing the heart rate, it reduces the heart's workload and oxygen demand, allowing it to pump blood more efficiently.

What is the usual dosage for INAPURE 5 MG TABLET?

The typical starting dose for adults is 5 mg taken twice daily, once in the morning and once in the evening, with meals. Your doctor may adjust the dose after two weeks, aiming for a resting heart rate of 50-60 beats per minute, up to a maximum of 7.5 mg twice daily. It's crucial to take the tablet at the same time each day with food.

What are the possible side effects of INAPURE 5 MG TABLET?

Common side effects can include temporary visual disturbances, such as enhanced brightness or flashes (luminous phenomena), a slow heart rate (bradycardia), dizziness, headache, blurred vision, high blood pressure, and atrial fibrillation. Other possible side effects include nausea, abdominal pain, diarrhea, and ECG changes. If you experience severe symptoms like fainting or significant changes to your heartbeat, seek immediate medical attention.

Is INAPURE 5 MG TABLET safe during pregnancy or breastfeeding?

No, INAPURE 5 MG TABLET is considered unsafe and is not recommended for use during pregnancy as it may cause harm to the developing fetus. Similarly, it is not recommended while breastfeeding due to a lack of safety information and the potential for the drug to cause toxicity to the baby. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can INAPURE 5 MG TABLET be taken with other medications?

Certain medications can interact with INAPURE 5 MG TABLET. It should not be taken with strong CYP3A4 inhibitors, such as antifungals (e.g., ketoconazole, itraconazole), certain antibiotics (e.g., clarithromycin, erythromycin), HIV protease inhibitors (e.g., ritonavir, nelfinavir), and some heart medications (e.g., diltiazem, verapamil). Caution is also advised with moderate CYP3A4 inhibitors, CYP3A4 inducers (like rifampicin, phenytoin, St. John's wort), and other cardiac medicines such as digoxin, amiodarone, and beta-blockers. Always inform your doctor about all medications, supplements, and herbal products you are taking.

What precautions should be taken while using INAPURE 5 MG TABLET?

Avoid consuming grapefruit juice while on this medication as it can increase the concentration of Ivabradine in your blood. Do not stop taking the medicine abruptly without consulting your doctor, as this can worsen your condition. Use with caution if you have mild to moderate liver or kidney problems, or low blood pressure. It is not recommended if you have severe liver problems, very low blood pressure, sick sinus syndrome, third-degree AV block, or if your heart rate is controlled by a pacemaker. Since it may cause dizziness or blurred vision, avoid driving or operating machinery until you know how the medicine affects you.

What happens if a dose of INAPURE 5 MG TABLET is missed?

If you miss a dose of INAPURE 5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should INAPURE 5 MG TABLET be stored?

INAPURE 5 MG TABLET should be stored at room temperature (below 25°C or 30°C), protected from light and moisture. Keep the medication out of sight and reach of children and pets.