Oratil 125 Dt

ORATIL 125 DT

ORATIL 125 DT is an antibiotic medication manufactured by Macleods Pharmaceuticals Pvt. Ltd., primarily used to treat various bacterial infections.

• Name: Oratil 125 DT Tablet.

• Composition: The active ingredient is Cefuroxime (125mg). Cefuroxime is a powerful, broad-spectrum second-generation cephalosporin antibiotic.

• Uses: ORATIL 125 DT is prescribed for the management of a wide range of bacterial infections. These include:

  • Respiratory tract infections (e.g., bronchitis, pneumonia, pharyngitis, tonsillitis, sinusitis).
  • Throat infections.
  • Skin and soft tissue infections.
  • Ear infections.
  • Sinus infections.
  • Lung infections.
  • Urinary tract infections (UTIs), including uncomplicated UTIs and pyelonephritis.
  • Early stages of Lyme disease.
  • Uncomplicated gonorrhea. It can also be used to prevent infections from animal and human bite wounds and may be administered before surgical procedures as a preventive measure.

• Dosage and Administration: ORATIL 125 DT should be taken as directed by your physician. It can be administered after meals to enhance absorption and minimize the risk of stomach upset. The usual duration of treatment is 7-10 days. It is crucial to complete the entire prescribed course of medication and not to stop taking it or skip doses, even if symptoms improve, to ensure effective treatment and prevent antibiotic resistance. If vomiting occurs within 30 minutes of taking the dose, the same dose should be given again, but do not double the dose if it is already time for the next scheduled dose.

• Side Effects: Common side effects may include:

  • Fungal infection (e.g., candida overgrowth).
  • Headache.
  • Dizziness.
  • Diarrhea.
  • Nausea.
  • Stomach pain or abdominal pain.
  • Increased type of white blood cells (eosinophilia).
  • Increase in liver enzymes.
  • Skin rash and itching.
  • Unpleasant taste in the mouth. Contact your doctor if these side effects persist or worsen.

• Precautions:

  • Inform your doctor if you have kidney problems, are allergic to any antibiotics (especially cephalosporins), have previously experienced anemia after taking antibiotics, or are scheduled for any blood tests.
  • This medicine is not effective against viral infections.
  • Exercise caution if driving or operating machinery, as ORATIL 125 DT may cause dizziness.
  • If you are pregnant or breastfeeding, consult your doctor before using this medicine. If used during breastfeeding, the baby should be monitored for symptoms such as diarrhea and yeast infection.
  • Antacids containing aluminum and magnesium salts, or proton pump inhibitors, can reduce the absorption of ORATIL 125 DT. It is advised to take ORATIL 125 DT at least 1 hour before or 2 hours after taking such medications.
  • Avoid consuming alcohol while taking ORATIL 125 DT as it may increase side effects.
  • Discontinue use and seek immediate medical attention if you experience a rash, itchy skin, swelling of the face and mouth, or difficulty breathing.

• Storage: Store ORATIL 125 DT in a cool and dry place, away from direct sunlight, at room temperature (below 30°C or between 10ºC to 25ºC). Keep it out of reach of children.

ORATIL 125 DT by Macleods Pharmaceuticals Pvt. Ltd. contains Cefuroxime 125mg as its active ingredient and is an antibiotic used to treat various bacterial infections.

Here are some frequently asked questions about ORATIL 125 DT:

What is ORATIL 125 DT used for?

ORATIL 125 DT is a broad-spectrum antibiotic used to treat a wide range of bacterial infections. These include infections of the lungs (such as pneumonia and bronchitis), ears (otitis media), nose, throat (pharyngitis, tonsillitis, sinusitis), skin and soft tissues (like impetigo), urinary tract, bones, and joints. It is also prescribed for gonorrhea and early Lyme disease, and can be used to prevent infections after animal or human bites and before surgical procedures. This medication is not effective against viral infections like the common cold or flu.

How does ORATIL 125 DT work?

ORATIL 125 DT contains Cefuroxime, which belongs to a class of antibiotics called cephalosporins. It works by interfering with the formation of the bacterial cell wall, a crucial protective layer for bacteria. By inhibiting cell wall synthesis, Cefuroxime prevents bacteria from growing and multiplying, ultimately leading to their death and clearing the infection.

What is the usual dosage for ORATIL 125 DT?

The dosage of ORATIL 125 DT depends on the type and severity of the infection, as well as the patient's age and weight. For adults and teenagers, typical oral dosages of cefuroxime tablets range from 250 mg to 500 mg, taken twice a day for 10 days for most infections. A single 1-gram dose may be used for gonorrhea, and 500 mg every 12 hours for 20 days for early Lyme disease. For children aged 3 months to 12 years, when taking the oral suspension, the dose is typically based on body weight, usually 20 to 30 mg per kilogram of body weight per day, divided into two doses, for 10 days, not exceeding 1000 mg daily. For otitis media, children under 2 years may take 125mg twice daily, while those over 2 years may take 250mg twice daily. Tablets should be swallowed whole and not crushed because they have a strong, bitter taste. It's important to note that cefuroxime tablets and oral suspension are absorbed differently and cannot be interchanged on a milligram-for-milligram basis. Oral suspension should generally be taken with food to improve absorption and reduce stomach upset. Always follow your doctor's specific instructions for dosage and duration of treatment.

What are the possible side effects of ORATIL 125 DT?

Common side effects include diarrhea, nausea, vomiting, abdominal pain, headache, rash, hives, vaginitis, mouth ulcers, dizziness, and stomach upset.

More serious side effects, though rare, require immediate medical attention. These include severe allergic reactions (such as hives, difficulty breathing, wheezing, or swelling of the face, throat, tongue, lips, or eyes), severe stomach pain, watery or bloody diarrhea (which can occur even months after treatment), yellowing of the skin or eyes (jaundice), fever, sore throat, burning in the eyes, a spreading red or purple skin rash that blisters, chills, muscle pain, lightheadedness, problems with hearing, seizures, little or no urination, painful or difficult urination, swelling in the feet or ankles, unusual tiredness or weakness, and signs of liver or kidney problems.

Is ORATIL 125 DT safe during pregnancy or breastfeeding?

Pregnancy: Cefuroxime is classified as an FDA pregnancy category B drug. Animal reproduction studies have shown no evidence of harm to the fetus. However, there are no adequate and well-controlled studies in pregnant women. Therefore, ORATIL 125 DT should be used during pregnancy only if clearly needed and after a discussion with your doctor.

Breastfeeding: Cefuroxime is excreted in small quantities in human breast milk. While generally considered acceptable in nursing mothers, caution is advised. There is a potential risk of adverse effects in breastfed infants, such as diarrhea or thrush. Your doctor will weigh the benefits and risks and may recommend monitoring the infant or suggest an alternative medication.

Can ORATIL 125 DT be taken with other medications?

Yes, ORATIL 125 DT can interact with other medications. It is important to inform your doctor about all prescription, non-prescription, vitamin, nutritional supplement, and herbal products you are taking or plan to take.

• Antacids (containing aluminum or magnesium, H2-blockers, proton pump inhibitors): These can reduce the absorption of cefuroxime, making it less effective. It is recommended to take cefuroxime at least 1 hour before or 2 hours after taking antacids.
• Probenecid: This medication can increase the concentration of cefuroxime in the blood, and co-administration is generally not recommended.
• Warfarin (blood thinners): Cefuroxime may interact with warfarin, potentially increasing the risk of bleeding.
• Certain other antibiotics (e.g., amikacin, gentamicin, tobramycin, other cephalosporins): Taking these with cefuroxime may increase the risk of nephrotoxicity (kidney damage).
• Live bacterial vaccines (e.g., typhoid vaccine): Cefuroxime may reduce the effectiveness of live bacterial vaccines. Inform your healthcare professional if you are using cefuroxime before any immunizations.
• Oral Contraceptives: Cefuroxime may decrease the effectiveness of oral birth control pills.

What precautions should be taken while taking ORATIL 125 DT?

• Do not use ORATIL 125 DT for viral infections, as it is only effective against bacteria.
• Complete the entire prescribed course of medication, even if your symptoms improve sooner. Stopping the antibiotic early can lead to the infection returning and potentially becoming harder to treat (antibiotic resistance).
• Inform your doctor if you have any known allergies, especially to penicillin or other cephalosporin antibiotics.
• Use with caution if you have a history of kidney disease, intestinal disease (particularly colitis), or severe diarrhea.
• ORATIL 125 DT may cause dizziness or drowsiness. Exercise caution when driving or operating machinery, and limit alcoholic beverages.
• Prolonged or repeated use of this medication may result in new fungal infections, such as oral thrush or vaginal yeast infections.
• Inform your medical doctor that you are taking cefuroxime before any medical tests, as it can interfere with certain blood and urine glucose tests.

What happens if a dose of ORATIL 125 DT is missed?

If you miss a dose of ORATIL 125 DT, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this could lead to increased side effects.

How should ORATIL 125 DT be stored?

ORATIL 125 DT tablets should be stored in a closed container at room temperature, away from heat, moisture, and direct light. If you have the oral suspension, it should be stored in the refrigerator. Any unused oral suspension should be discarded after 10 days. Do not freeze the oral suspension. Keep all medicines out of the reach of children.