Magadol Tablet (10 Tab)

MAGADOL TABLET (10 TAB) by ALEMBIC PHARMACEUTICALS LIMITED

Magadol Tablet is a combination medication primarily used for pain relief and reducing inflammation. It is manufactured by Alembic Pharmaceuticals Ltd..

• Composition: Each tablet contains Diclofenac 50 mg and Paracetamol (Acetaminophen) 325 mg. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks chemical messengers causing pain and swelling. Paracetamol acts as a mild analgesic and antipyretic, enhancing pain relief and reducing fever.

• Uses: Magadol Tablet is prescribed for short-term relief from various painful conditions and inflammation. These include:

  • Rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.
  • Muscle pain, back pain, toothache, earache, throat pain.
  • Headache, menstrual pain, sprains, and strains.

• Dosage and Administration: The typical adult dosage is one tablet, taken with food, up to three times a day, or as advised by a doctor. Taking it with food helps prevent stomach upset. Tablets should be swallowed whole and not crushed, chewed, or broken. Do not exceed the recommended dosage or duration.

• Side Effects: Common side effects may include nausea, vomiting, stomach pain/epigastric pain, heartburn, diarrhea, loss of appetite, and indigestion. Dizziness and sleepiness are also possible. Serious but less common side effects that require immediate medical attention include severe stomach pain, black or blood-stained stools, vomiting blood, and swelling of the ankles, feet, hands, lips, or throat.

• Precautions: Magadol Tablet is contraindicated in individuals with known allergies to diclofenac, paracetamol, or other ingredients. It should be avoided in patients with severe heart problems, liver or kidney disorders, or a history of stomach ulcers and bleeding. Caution is advised in patients with asthma. It is unsafe to use during the third trimester of pregnancy, and consultation with a doctor is necessary during pregnancy or breastfeeding. Alcohol consumption should be avoided due to increased risk of liver damage and stomach irritation. It may cause dizziness, affecting the ability to drive or operate machinery. Inform your doctor about all other medications being taken to prevent potential drug interactions.

• Storage: Store Magadol Tablet in a cool, dry place, below 30°C, protected from light and moisture, and out of reach of children.

MAGADOL Tablet is a combination medicine containing Diclofenac (50mg) and Paracetamol (325mg or 500mg, depending on the specific formulation). It is primarily used to relieve pain, inflammation, and fever.

What is MAGADOL Tablet used for?

MAGADOL Tablet is used for the short-term relief of pain, inflammation, and swelling associated with various conditions. These include painful musculoskeletal joint conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also effective in relieving muscle pain, back pain, toothache, ear pain, throat pain, headaches, menstrual pain, sprains, and strains.

How does MAGADOL Tablet work?

MAGADOL Tablet works due to the combined action of its two active ingredients: Diclofenac and Paracetamol. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the production of chemical messengers called prostaglandins, which are responsible for causing pain, fever, and inflammation at the site of injury or damage. Paracetamol (also known as acetaminophen) acts as a mild pain reliever and fever reducer. It helps to increase the body's pain threshold and reduces fever by acting on specific areas of the brain, thereby enhancing the pain-relieving effect of Diclofenac.

What is the usual dosage for MAGADOL Tablet?

The usual adult dosage of MAGADOL Tablet is one tablet, taken with food, up to three times a day, or 1 tablet every 6-8 hours, depending on the severity of the pain and as prescribed by your doctor. It is crucial to take the tablet with food to minimize the risk of stomach upset. Always swallow the tablet whole; do not crush, chew, or break it, and do not exceed the recommended dosage without consulting your doctor.

What are the possible side effects of MAGADOL Tablet?

Common side effects may include nausea, vomiting, stomach pain/upset, loss of appetite, heartburn, indigestion, diarrhea, dizziness, light-headedness, malaise, itchy skin (pruritis), and rash. While most of these are usually mild and temporary, some potentially serious side effects can occur, such as liver dysfunction and an increased risk of heart attack or stomach ulcers/bleeding, especially with prolonged use. If you experience persistent or worsening side effects, or severe symptoms like difficulty breathing, facial swelling, severe abdominal pain, red or black tarry stools, or coughing up blood, seek immediate medical attention.

Is MAGADOL Tablet safe during pregnancy or breastfeeding?

MAGADOL Tablet is generally not recommended during pregnancy, particularly in the last three months, due to potential risks such as heart defects in the fetus, delayed delivery, or an increased risk of bleeding. If you are pregnant or planning a pregnancy, consult your doctor before taking this medicine. For breastfeeding mothers, Diclofenac can be excreted in breast milk, so it's advisable to consult your doctor to assess the potential risks and benefits before use.

Can MAGADOL Tablet be taken with other medications?

MAGADOL Tablet can interact with various medications. It is crucial to inform your doctor about all other medicines, supplements, and herbal preparations you are taking to avoid potential drug interactions.

• Avoid or use with caution with:
  • Other medicines containing Paracetamol, as this increases the risk of liver damage.
  • Blood thinners (e.g., Warfarin, Aspirin, Coumarin), as it can increase the risk of bleeding.
  • Other anti-inflammatory medications (e.g., Ibuprofen, Naproxen, Celecoxib, Meloxicam) due to an increased risk of gastrointestinal side effects like stomach bleeding and ulcers.
  • Medicines for high blood pressure (antihypertensives, ACE inhibitors, diuretics), as it can reduce their effectiveness or increase the risk of kidney damage.
  • Lithium and Digoxin, as MAGADOL Tablet can increase their levels in the blood, potentially leading to toxic effects.
  • Corticosteroids, due to an increased risk of gastrointestinal bleeding.

What precautions should be taken while using MAGADOL Tablet?

Inform your doctor about any pre-existing medical conditions, especially heart, kidney, or liver problems, stomach ulcers, bleeding disorders, asthma, or autoimmune diseases. It is not recommended for use in children under 14 years of age, and elderly patients may require closer monitoring due to increased susceptibility to side effects. Avoid consuming alcohol while taking this medicine as it can increase the risk of liver damage, stomach bleeding, and enhance dizziness or drowsiness. Be cautious when driving or operating machinery if you experience dizziness or drowsiness. Do not self-medicate or use the medicine beyond the prescribed duration.

What happens if a dose of MAGADOL Tablet is missed?

If you miss a dose of MAGADOL Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should MAGADOL Tablet be stored?

Store MAGADOL Tablet in a cool and dry place, preferably below 30°C, away from direct sunlight and moisture. Always keep the medicine out of the reach of children and pets. Ensure that you use the product before its expiry date.