Glura Mp 500 Tab

GLURA MP 500 Tablet SR

GLURA MP 500 Tablet SR, manufactured by Eris Lifesciences Limited, is a combination medication primarily used for the management of Type 2 diabetes mellitus in adults.

Composition Each sustained-release tablet contains:

• Metformin Hydrochloride: 500 mg
• Pioglitazone: 15 mg
• Sitagliptin Phosphate: 100 mg

Uses GLURA MP 500 Tablet SR is prescribed as an adjunct to diet and exercise to improve glycemic control in adults with Type 2 diabetes. It helps to control blood sugar levels and reduce the risk of serious complications associated with diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs. The medicine works by decreasing glucose production in the liver, reducing glucose absorption from food, increasing the body's response to insulin, and enhancing insulin-dependent glucose utilization. Sitagliptin also increases incretins that stimulate insulin release and signal the liver to stop producing glucose when blood sugar is high.

Dosage and Administration This medicine should be taken orally as advised by your doctor. It can be taken with or without food, but it is often recommended to take it with meals to minimize gastrointestinal side effects. Swallow the tablet whole; do not chew, crush, or break it. It is crucial to take it regularly at the same time each day to achieve the most benefit and maintain consistent medication levels. Do not alter the dosage or stop taking the medicine without consulting your doctor.

Side Effects Common side effects may include:

• Nausea
• Vomiting
• Diarrhea
• Flatulence
• Abdominal pain
• Constipation
• Headache
• Edema (fluid retention)
• Hypoglycemia (low blood sugar), especially if taken with other diabetes medicines or alcohol.

If side effects are worrisome or persistent, consult your doctor.

Precautions Inform your doctor if you have kidney disease, heart problems (including heart failure), liver problems, pancreatitis, Type 1 diabetes, diabetic ketoacidosis, high triglycerides, gallstones, bladder cancer, or consume a lot of alcohol. Pregnant or breastfeeding women should consult their doctor before use. Limit alcohol intake while on this medication as it can increase the risk of low blood sugar. Regular monitoring of blood sugar and kidney function is recommended. This medicine may interact with other medications, so inform your doctor about all current prescriptions, over-the-counter drugs, and herbal supplements.

Storage Store GLURA MP 500 Tablet SR in a cool, dry place away from direct sunlight, at room temperature (20-25°C or below 30°C). Keep it out of the reach and sight of children.

Here are the most frequently asked questions about GLURA MP 500 TAB:

What is GLURA MP 500 TAB used for?

GLURA MP 500 TAB is an anti-diabetic medicine primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus. It is typically used as an adjunct to diet and exercise to improve glycemic control and help prevent complications of diabetes such as kidney damage, nerve problems, and eye problems.

How does GLURA MP 500 TAB work?

GLURA MP 500 TAB is a combination medicine containing three active ingredients: Metformin, Pioglitazone, and Sitagliptin.

• Metformin works by decreasing the amount of glucose produced by the liver, reducing glucose absorption from food in the intestines, and improving the body's response to insulin.
• Pioglitazone enhances the body's sensitivity to insulin, allowing cells in muscles and fat tissues to use insulin more effectively. It also inhibits the liver's production of new glucose.
• Sitagliptin increases certain natural substances in the body called incretin hormones, which help the pancreas release more insulin and signal the liver to stop producing glucose when blood sugar levels are high. Together, these components work through different mechanisms to lower blood glucose levels and improve overall blood sugar control.

What is the usual dosage for GLURA MP 500 TAB?

The dosage of GLURA MP 500 TAB is determined by your doctor based on your condition and blood sugar levels. It is important to take this medicine exactly as advised by your doctor, usually once or twice daily. It should be swallowed whole with a glass of water, typically taken with meals to minimize stomach upset. Do not crush, chew, or break the tablet.

What are the possible side effects of GLURA MP 500 TAB?

Common side effects of GLURA MP 500 TAB include nausea, vomiting, diarrhea, stomach upset, flatulence, abdominal pain, constipation, and headache. These effects are usually mild and tend to improve over time. Low blood sugar (hypoglycemia) is a possible side effect, especially if taken with other diabetes medicines or if meals are delayed or missed.

Is GLURA MP 500 TAB safe during pregnancy or breastfeeding?

Caution is advised when taking GLURA MP 500 TAB during pregnancy or breastfeeding. Information regarding its use during pregnancy is limited, and animal studies have shown harmful effects on the developing baby. It is probably unsafe during breastfeeding as it may pass into breast milk. Always consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding.

Can GLURA MP 500 TAB be taken with other medications?

GLURA MP 500 TAB can interact with other medications, including certain antibiotics, antifungals, diuretics, heart medications (like propranolol), painkillers (like aspirin, ibuprofen), high blood pressure medicines (like nifedipine), thyroid hormones, and antacids. It is crucial to inform your doctor about all other medicines, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using GLURA MP 500 TAB?

Before taking GLURA MP 500 TAB, inform your doctor if you have type 1 diabetes, kidney problems (it is not recommended for moderate to severe kidney problems), liver problems, heart problems (including congestive heart failure), diabetic ketoacidosis, pancreatitis, high triglycerides, gallstones, alcoholism, bladder cancer, or bone problems. Limit alcohol consumption as it can increase the risk of low blood sugar and a rare but serious condition called lactic acidosis. Monitor your blood sugar levels regularly and be aware of the symptoms of hypoglycemia.

What happens if a dose of GLURA MP 500 TAB is missed?

If you miss a dose of GLURA MP 500 TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should GLURA MP 500 TAB be stored?

GLURA MP 500 TAB should be stored in a cool and dry place, away from direct sunlight. The recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC. Keep it out of reach and sight of children.