Ziglim M 2 Mg Tablet (15 Tab)

ZIGLIM M 2 MG TABLET (15 TAB) by FDC LIMITED

ZIGLIM M 2 MG TABLET is a combination medication prescribed for the management of type 2 diabetes mellitus in adults. It is manufactured by FDC LIMITED.

Composition Each tablet contains:

• Glimepiride: 2 mg
• Metformin: 500 mg

Uses ZIGLIM M 2 MG TABLET is used to manage high blood sugar levels in adults with type 2 diabetes when diet and exercise alone, or treatment with a single antidiabetic agent like glimepiride or metformin, are insufficient. It aids in improving glycemic control and reducing the risk of diabetes-related complications such as kidney damage, eye problems, and nerve issues.

Dosage and Administration This medicine should be taken as directed by a healthcare professional. Typically, it is taken once or twice daily with meals, often with the first main meal. The tablet should be swallowed whole with water and not crushed, chewed, or broken. Do not alter the prescribed dosage or discontinue the medication without consulting your doctor.

Side Effects

• Common Side Effects: Hypoglycemia (low blood sugar), diarrhea, nausea, vomiting, abdominal pain, headache, taste disturbance, and loss of appetite.
• Serious Side Effects (Rare): Lactic acidosis (symptoms include muscle pain/weakness, dizziness, fatigue, cold sensation in limbs, difficulty breathing, persistent stomach pain, vomiting, and slow heart rate), inflammation of the liver (jaundice), severe allergic reactions, and long-term use may lead to vitamin B12 deficiency.

Precautions

• Avoid ZIGLIM M 2 MG TABLET if you have type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, metabolic acidosis, severe infections, shock, heart or lung failure, or an allergy to its ingredients.
• Not recommended for use during pregnancy or breastfeeding.
• Avoid alcohol consumption as it can increase the risk of low blood sugar and lactic acidosis.
• Regular monitoring of blood sugar levels is essential. Always carry a quick source of sugar (e.g., glucose tablets, fruit juice) to manage hypoglycemia.
• Consult your doctor if you experience symptoms like drowsiness, as it may impair your ability to drive or operate machinery.
• Inform your doctor about all existing medical conditions and current medications.

Storage Store the medicine below 30°C in a cool, dry place, away from direct sunlight. Keep it out of reach of children and pets.

Here are frequently asked questions about ZIGLIM M 2 MG TABLET:

What is ZIGLIM M 2 MG TABLET used for?

ZIGLIM M 2 MG TABLET is primarily used to treat adults with Type 2 Diabetes Mellitus. It is prescribed when diet and exercise alone are not sufficient to control blood sugar levels, or when glimepiride or metformin alone is not effective enough. This medication helps lower elevated blood glucose levels and reduces the risk of diabetes-related complications such as kidney damage, eye problems, nerve issues, heart disease, and stroke.

How does ZIGLIM M 2 MG TABLET work?

ZIGLIM M 2 MG TABLET is a combination medicine containing two active ingredients: Glimepiride (2 mg) and Metformin (500 mg). Glimepiride, a sulfonylurea, works by stimulating the beta cells in the pancreas to release more insulin, a hormone that helps lower blood glucose levels. Metformin, a biguanide, acts by reducing the amount of glucose produced by the liver, decreasing glucose absorption from the intestines, and improving the body's sensitivity to insulin in muscle and fat tissues. Together, these actions effectively help to manage blood sugar levels.

What is the usual dosage for ZIGLIM M 2 MG TABLET?

ZIGLIM M 2 MG TABLET is typically taken once or twice daily with meals, often with the first meal of the day. It is crucial to swallow the tablet whole with a glass of water and not to crush or chew it. Your doctor will determine the appropriate dosage based on your individual needs and how well your blood sugar levels are controlled. It is important to take this tablet at the same time daily to achieve optimal therapeutic benefits and never alter the dose or stop taking the medicine without consulting your doctor.

What are the possible side effects of ZIGLIM M 2 MG TABLET?

Common side effects include hypoglycemia (low blood sugar), diarrhea, nausea, vomiting, abdominal pain, headache, and a metallic taste. Symptoms of hypoglycemia can include sweating, dizziness, headache, shaking, irritability, hunger, fast heart rate, and feeling anxious or shaky. A serious but rare side effect is lactic acidosis, which involves an excessive build-up of lactic acid in the blood. Symptoms of lactic acidosis may include deep or rapid breathing, persistent nausea, vomiting, stomach pain with muscle cramps, severe tiredness, reduced body temperature, and a low heartbeat. Long-term use may also lead to Vitamin B12 deficiency. Consult your doctor if any side effects persist or worsen.

Is ZIGLIM M 2 MG TABLET safe during pregnancy or breastfeeding?

No, ZIGLIM M 2 MG TABLET is generally not recommended during pregnancy as it may cause harm to the unborn baby. If you are pregnant or planning to conceive, your doctor may suggest alternative treatments, such as insulin, for blood sugar control. Similarly, this medicine is not recommended for use while breastfeeding as it may pass into breast milk and potentially cause adverse effects in the baby. Always consult your doctor for safe treatment options if you are breastfeeding.

Can ZIGLIM M 2 MG TABLET be taken with other medications?

ZIGLIM M 2 MG TABLET can interact with several other medications. It is essential to inform your doctor about all prescription and over-the-counter drugs, as well as herbal supplements you are taking. Notable interactions may occur with:

• Other antidiabetic medicines: May increase the risk of hypoglycemia.
• Blood pressure medications: Such as beta-blockers (atenolol, propanolol, clonidine) and calcium channel blockers.
• Heart failure medications, blood thinners, and thyroid medicines.
• Certain antibiotics, antifungals, and anti-infectives.
• Painkillers (NSAIDs like phenylbutazone) and anti-inflammatory drugs.
• Oral contraceptives, antacids (ranitidine), and some antipsychotic medicines (reserpine).
• CYP2C9 inhibitors like fluconazole and amiodarone, which can increase glimepiride levels and hypoglycemia risk.
• High-fiber foods may slow the absorption of metformin.
• Grapefruit juice should also be avoided.

What precautions should be taken while taking ZIGLIM M 2 MG TABLET?

• Alcohol: Avoid or limit alcohol consumption during treatment, as it significantly increases the risk of low blood sugar and can lead to serious complications like lactic acidosis.
• Driving: If you experience symptoms of low blood sugar such as drowsiness, confusion, or dizziness, avoid driving or operating machinery as your alertness may be impaired.
• Kidney and Liver Disease: This medicine is not recommended for individuals with severe kidney or liver failure. For mild to moderate conditions, it should be used with caution, requiring dose adjustments and regular monitoring of kidney and liver function by your doctor.
• Other Conditions: Inform your doctor if you have Type 1 diabetes, diabetic ketoacidosis, metabolic acidosis, severe infections, dehydration, shock, heart failure, or have recently had a heart attack, as this medicine may be contraindicated.
• Hypoglycemia: To prevent low blood sugar, do not skip meals, avoid fasting, and always carry a quick source of sugar (like fruit juice or glucose candy).
• Regular Monitoring: Consistent monitoring of your blood sugar levels is essential while on this medication.
• Lifestyle: This medication should be used in conjunction with a healthy diet and regular exercise as advised by your doctor.
• Surgery: Inform your doctor about your diabetes treatment if you are scheduled for surgery under general anesthesia.
• Photosensitivity: Some sulfonylurea drugs can cause increased sensitivity to the sun; consider using sunscreen.

What happens if a dose of ZIGLIM M 2 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Frequently missing doses can lead to elevated blood sugar levels and increase the risk of long-term diabetes complications.

How should ZIGLIM M 2 MG TABLET be stored?

ZIGLIM M 2 MG TABLET should be stored in a cool, dry place, protected from moisture and direct sunlight. It should be kept out of the reach and sight of children. The recommended storage temperature is below 25°C or 30°C.