Zita Piomet 500 Mg Tab

ZITA PIOMET 500 MG Tablet is a combination medication primarily used for the management of Type 2 Diabetes Mellitus. It is marketed by GLENMARK-DIABETES CARE DIV.

Composition

ZITA PIOMET 500 MG Tablet contains a combination of three active ingredients:

• Metformin: 500 mg (sustained release where indicated)
• Pioglitazone: 15 mg
• Teneligliptin: 20 mg

Uses

ZITA PIOMET 500 MG Tablet is prescribed to improve glycemic control in adults with Type 2 Diabetes Mellitus. It is particularly used when diet, exercise, and single or dual anti-diabetic therapies do not adequately control blood sugar levels. The medicine works by reducing glucose production in the liver, delaying sugar absorption from the intestines, increasing the body's sensitivity to insulin, and enhancing insulin release from the pancreas.

Dosage and Administration

This medication should be taken as prescribed by your doctor, usually once or twice daily, preferably with meals to minimize stomach upset. The tablet should be swallowed whole with water and not chewed, crushed, or broken. It is crucial to maintain consistency by taking the medicine at the same time(s) each day.

Side Effects

Common side effects may include:

• Stomach upset, nausea, vomiting, diarrhea, or abdominal pain
• Hypoglycemia (low blood sugar levels)
• Headache
• Weight gain or peripheral edema (swelling in limbs)
• Upper respiratory tract infection
• Metallic taste or changes in taste Serious side effects, though rare, can include lactic acidosis, signs of liver damage, heart failure symptoms, and bladder cancer symptoms. Consult your doctor if any side effects persist or worsen.

Precautions

• Allergies: Avoid if allergic to any of its components.
• Pregnancy and Breastfeeding: Generally not recommended; consult a doctor.
• Kidney/Liver Disease: Use with caution, and dose adjustments may be needed. Contraindicated in severe kidney or liver impairment.
• Heart Conditions: Caution is advised in patients with heart disease; contraindicated in congestive heart failure requiring pharmacologic treatment.
• Alcohol: Avoid excessive alcohol consumption as it increases the risk of hypoglycemia and lactic acidosis.
• Drug Interactions: Inform your doctor about all medications, supplements, and herbal remedies being taken, especially diuretics, corticosteroids, oral contraceptives, and protease inhibitors, as these can affect blood sugar control.
• Children and Elderly: Not recommended for children below 18 years. Elderly patients may require caution and dose adjustments.
• Lactic Acidosis: Caution is advised as metformin accumulation can lead to lactic acidosis, especially with hepatic insufficiency.

Storage

Store in a cool and dry place, away from direct sunlight, at a temperature between 10°C and 30°C. Keep out of the sight and reach of children.

What is Zita-Piomet 500 Tablet used for?

Zita-Piomet 500 Tablet is a combination medicine used to treat type 2 diabetes mellitus in adults. It is typically prescribed when diet, exercise, and other single or dual antidiabetic therapies do not adequately control blood sugar levels. This medicine helps improve glycemic control, lower high blood sugar levels, and enhance insulin sensitivity.

How does Zita-Piomet 500 Tablet work?

Zita-Piomet 500 Tablet contains three active ingredients: Metformin, Teneligliptin, and Pioglitazone.

• Metformin works by reducing the sugar production by cells in the liver, delaying sugar absorption from the intestines, and increasing the body's sensitivity to insulin.
• Teneligliptin decreases hormones that raise blood glucose levels and increases insulin release from the pancreas.
• Pioglitazone helps the body make better use of the insulin it produces by increasing insulin sensitivity in muscle, fat, and liver tissues.

What is the usual dosage for Zita-Piomet 500 Tablet?

The dosage of Zita-Piomet 500 Tablet is determined by your doctor based on your individual needs, blood glucose levels, and other medications you may be taking. It's crucial to follow your physician's prescribed dosage and schedule strictly. The medicine is usually taken with or immediately after meals to minimize gastrointestinal side effects.

What are the possible side effects of Zita-Piomet 500 Tablet?

Common side effects may include low blood sugar levels (hypoglycemia), stomach upset, nausea, vomiting, diarrhea, constipation, headache, dizziness, changes in taste, and swelling in the limbs (edema). More serious but rare side effects can include liver problems or heart failure. It is important to consult your doctor if any side effects persist or worsen.

Is Zita-Piomet 500 Tablet safe during pregnancy or breastfeeding?

Zita-Piomet 500 Tablet is generally not recommended for use during pregnancy and is contraindicated for breastfeeding women. If you are pregnant, planning to conceive, or breastfeeding, it is essential to inform your doctor, who will weigh the benefits against the risks and may suggest safer alternatives.

Can Zita-Piomet 500 Tablet be taken with other medications?

Yes, Zita-Piomet 500 Tablet can interact with other medications. It is crucial to inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential interactions. Some medications, such as other antidiabetic agents, iodine contrast media, beta-2 agonists, corticosteroids, diuretics, and certain pain and inflammation medicines, may interact with Zita-Piomet 500 Tablet.

What precautions should be taken while taking Zita-Piomet 500 Tablet?

Several precautions should be taken:

• Alcohol: Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia and lactic acidosis.
• Medical Conditions: Inform your doctor if you have a history of liver disease, kidney disease, heart problems (especially congestive heart failure), active bladder cancer, or a history of bladder cancer.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is recommended.
• Children: This medicine is not recommended for children under 18 years of age.
• Lifestyle: The medication works best when combined with a healthy diet, regular exercise, and maintaining a healthy weight.

What happens if a dose of Zita-Piomet 500 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Zita-Piomet 500 Tablet be stored?

Zita-Piomet 500 Tablet should be stored in a cool and dry place, away from direct sunlight, typically below 30°C (86°F) or at room temperature (20-25°C). Keep it out of the sight and reach of children.