Isanerve Nt Tab

ISANERVE NT TAB

ISANERVE NT TAB by ISAKURA HEALTHCARE DIV. is a combination medicine formulated to address neuropathic pain and associated conditions.

• Name:

  • Brand Name: Isanerve NT Tab
  • Common Name: Pregabalin, Nortriptyline, and Methylcobalamin Tablets

• Composition: Each tablet contains:

  • Pregabalin (75mg)
  • Nortriptyline (10mg)
  • Methylcobalamin (1500mcg)

• Uses: Isanerve NT is primarily used in the treatment of neuropathic pain, which is chronic pain caused by nerve damage. It is prescribed for conditions such as:

  • Diabetic neuropathy
  • Postherpetic neuralgia (shingles)
  • Spinal cord injury
  • Fibromyalgia
  • Peripheral neuropathy
  • Certain chronic pain syndromes, including lower back pain and migraine prevention

• Dosage and Administration: This medicine should be taken orally with or without food, as advised by a doctor. It is recommended to take it at the same time each day for consistent levels in the body. The tablet should be swallowed whole and not chewed, crushed, or broken. Patients should not stop taking the medicine suddenly without consulting their doctor, as this may lead to withdrawal symptoms or a worsening of symptoms.

• Side Effects: Common side effects may include:

  • Dizziness, sleepiness, and fatigue
  • Weight gain, increased hunger
  • Dry mouth, constipation, nausea, vomiting, diarrhea, stomach upset
  • Blurred vision
  • Peripheral edema (swelling of lower legs and hands)
  • Uncoordinated body movements, decreased appetite, difficulty in urination
  • Orthostatic hypotension (sudden lowering of blood pressure on standing), increased heart rate Serious side effects are rare but can include changes in body temperature, difficulty breathing, and mood changes.

• Precautions:

  • Alcohol: Concurrent use with alcohol is unsafe and can lead to excessive drowsiness.
  • Driving/Operating Machinery: Avoid activities requiring alertness, such as driving, as it may cause drowsiness and affect ability.
  • Pregnancy and Breastfeeding: It is generally considered unsafe during pregnancy and breastfeeding; consult a doctor.
  • Kidney/Liver Disease: Use with caution in patients with kidney disease; dose adjustments may be needed. Use in liver disease patients may require dose adjustment.
  • Children: Safety and effectiveness have not been established for children.
  • Interactions: Inform your doctor about all other medications being taken to avoid potential drug interactions.

• Storage: Store Isanerve NT Tab in a cool, dry place, out of the sight and reach of children.

What is ISANERVE NT TAB used for?

ISANERVE NT TAB is a combination medicine primarily used to treat neuropathic pain, which is pain caused by nerve damage. This includes conditions like diabetic neuropathy, postherpetic neuralgia (shingles), sciatica, and pain from spinal cord injuries. It also helps manage associated symptoms such as mood changes, sleep problems, and tiredness, and can be used for chronic pain syndromes and fibromyalgia.

How does ISANERVE NT TAB work?

ISANERVE NT TAB contains three active ingredients: Pregabalin, Nortriptyline, and Methylcobalamin. Pregabalin is an alpha 2 delta ligand that reduces pain by modulating calcium channel activity in nerve cells. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers (serotonin and noradrenaline) in the brain, which helps stop the movement of pain signals. Methylcobalamin is a form of vitamin B that aids in the production of myelin, a substance that protects nerve fibers and helps regenerate damaged nerve cells. Together, these components work to relieve nerve pain.

What is the usual dosage for ISANERVE NT TAB?

The exact dosage of ISANERVE NT TAB should be determined and advised by your doctor based on your specific medical condition. It is typically taken orally, with or without food, at the same time each day to maintain consistent medicine levels in the body. Do not chew, crush, or break the tablet, and always follow your doctor's instructions regarding the dose and duration of treatment.

What are the possible side effects of ISANERVE NT TAB?

Common side effects can include dizziness, sleepiness, nausea, blurred vision, peripheral edema (swelling of the lower legs and hands), weight gain, and dry mouth. Other potential side effects may include constipation, uncoordinated body movements, decreased appetite, difficulty in urination, orthostatic hypotension (sudden lowering of blood pressure on standing), and increased heart rate. Most common side effects do not require medical attention and should resolve over time. Serious side effects are rare but can include changes in body temperature, difficulty breathing, and mood changes, which require immediate medical attention.

Is ISANERVE NT TAB safe during pregnancy or breastfeeding?

ISANERVE NT TAB is generally considered unsafe to use during pregnancy, as animal studies have indicated harmful effects on the developing baby, and limited human data also suggests potential risks. For breastfeeding mothers, it is probably unsafe as limited human data suggests the drug may pass into breastmilk and harm the baby. Always consult your doctor, who will weigh the potential benefits against the risks before prescribing this medicine during pregnancy or breastfeeding.

Can ISANERVE NT TAB be taken with other medications?

It is crucial to inform your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements, as many can interact with ISANERVE NT TAB. Co-administration with certain drugs like dronedarone, alprazolam, baclofen, buspirone, clozapine, tramadol, and zolpidem can lead to interactions.

What precautions should be taken while taking ISANERVE NT TAB?

You should avoid consuming alcohol and grapefruit juice while taking ISANERVE NT TAB, as it can lead to excessive drowsiness and potentially increase side effects. Due to the possibility of dizziness, sleepiness, or blurred vision, avoid driving or operating heavy machinery until you understand how the medication affects you. Use with caution if you have kidney or liver disease, as dose adjustments may be necessary. Do not stop taking the medicine suddenly without consulting your doctor, as this can lead to withdrawal symptoms.

What happens if a dose of ISANERVE NT TAB is missed?

If you miss a dose of ISANERVE NT TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects.

How should ISANERVE NT TAB be stored?

ISANERVE NT TAB should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Properly dispose of any unused medication to prevent accidental ingestion.