Shringlim M1 Tab

SHRINGLIM M1 TAB by SHREEDA PHARMACEUTICALS DIV

Name

• Common Name: Glimepiride and Metformin Tablets
• Brand Name: SHRINGLIM M1 TAB (SHREEDA PHARMACEUTICALS DIV)

Composition

SHRINGLIM M1 TAB is a combination of two antidiabetic medicines:

• Glimepiride: 1mg
• Metformin: 500mg

Uses

SHRINGLIM M1 TAB is primarily used for the treatment of Type 2 Diabetes Mellitus in adults. It helps control blood sugar levels when diet and exercise alone are not sufficient, or when glimepiride or metformin alone cannot adequately control blood sugar. This medication works by increasing the amount of insulin the body produces (from the pancreas) and also by lowering glucose production in the liver, delaying glucose absorption from the intestines, and improving the body's sensitivity to insulin.

Dosage and Administration

This medicine is typically taken once a day with food. It should be taken regularly at the same time each day to achieve the most benefit. The tablet should be swallowed whole with a glass of water and not chewed, crushed, or broken. The exact dose will be determined by a doctor based on blood sugar levels and how the medicine is working. It is crucial to continue taking this medicine for the prescribed duration, even if blood sugar levels are controlled, to prevent complications.

Side Effects

Common Side Effects:

• Hypoglycemia (low blood sugar level), characterized by sweating, dizziness, headache, and shaking
• Nausea
• Stomach pain
• Diarrhea
• Altered taste
• Headache
• Weight gain

Serious Side Effects:

• Lactic acidosis, a medical emergency caused by increased levels of lactic acid in the blood, which is rare but potentially serious.
• Vitamin B12 deficiency with long-term use.

Precautions

• Hypoglycemia: Patients should be aware of the symptoms of low blood sugar and carry a fast-acting source of glucose (e.g., sugary food, fruit juice).
• Alcohol: Avoid alcohol consumption as it can increase the risk of low blood sugar levels and lactic acidosis.
• Kidney and Liver Disease: Use with caution in patients with kidney or liver disease. Dose adjustments may be needed, and it is generally not recommended for severe cases.
• Pregnancy and Breastfeeding: Not recommended for pregnant or breastfeeding women as it may harm the unborn baby or pass into breast milk.
• Type 1 Diabetes and Diabetic Ketoacidosis: This medication is not indicated for Type 1 Diabetes or diabetic ketoacidosis.
• Regular monitoring of blood sugar levels, kidney function tests, and blood cell counts is advisable.

Storage

Store SHRINGLIM M1 TAB in a cool, dry place away from direct sunlight. Keep it out of reach and sight of children. It should be stored at temperatures between 10ºC to 25ºC or below 30ºC.

What is SHRINGLIM M1 TAB used for?

SHRINGLIM M1 TAB is a combination medicine primarily used to treat Type 2 Diabetes Mellitus in adults. It helps manage blood sugar levels when diet and exercise alone are insufficient, or when glimepiride or metformin alone cannot adequately control blood sugar.

How does SHRINGLIM M1 TAB work?

This medicine contains two active ingredients: Glimepiride and Metformin. Glimepiride, a sulfonylurea, works by stimulating the pancreas to produce and release more insulin. Metformin, a biguanide, reduces glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin, thereby helping to remove sugar from the blood.

What is the usual dosage of SHRINGLIM M1 TAB?

The specific dose of SHRINGLIM M1 TAB is determined by your doctor, who may adjust it over time based on your blood sugar levels and how the medicine is working. It is generally taken once a day, with food, preferably with the first meal of the day, and should be swallowed whole without chewing, crushing, or breaking it. It's crucial to take it regularly at the same time each day for maximum benefit.

What are the possible side effects of SHRINGLIM M1 TAB?

Common side effects include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. More serious but rare side effects can include lactic acidosis, a medical emergency caused by increased lactic acid levels in the blood. Long-term use may also lead to vitamin B12 deficiency. Some individuals might experience weight gain.

Is SHRINGLIM M1 TAB safe during pregnancy or breastfeeding?

SHRINGLIM M1 TAB is generally considered unsafe for use during pregnancy as animal studies have shown harmful effects on the developing baby, and it may harm the unborn baby. It is also not recommended during breastfeeding because it may pass into breast milk and potentially cause adverse effects in the baby. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can SHRINGLIM M1 TAB be taken with other medications?

SHRINGLIM M1 TAB can interact with several medications. Other anti-diabetic medications (like insulin) can enhance its blood sugar-lowering effect, increasing the risk of hypoglycemia. Corticosteroids (e.g., prednisone) and thiazide diuretics (e.g., hydrochlorothiazide) can reduce its effectiveness by increasing blood sugar levels. Cimetidine can increase metformin levels, potentially enhancing its action and risk of side effects. Alcohol consumption should be avoided as it can lower blood sugar levels and increase the risk of lactic acidosis. It's essential to inform your doctor about all medications you are taking.

What precautions should be taken while using SHRINGLIM M1 TAB?

Do not take SHRINGLIM M1 TAB if you have Type 1 Diabetes Mellitus, diabetic ketoacidosis, or severe kidney or liver disease. Inform your doctor if you have a history of heart disease, low blood sugar, or circulation problems. Regular monitoring of blood sugar levels is crucial, and your doctor may also recommend blood tests to check blood cell counts and liver function. Be aware of the symptoms of hypoglycemia (sweating, dizziness, headache, shaking) and always carry a fast-acting source of glucose. This medicine may decrease alertness, so avoid driving if you feel dizzy or confused.

What happens if a dose of SHRINGLIM M1 TAB is missed?

If you miss a dose of SHRINGLIM M1 TAB, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Consult your doctor if you frequently miss doses.

How should SHRINGLIM M1 TAB be stored?

SHRINGLIM M1 TAB should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of the reach and sight of children and pets. Ensure the container is tightly closed.