Torglip D 5 Mg Tablet (10 Tab)

TORGLIP D 5 MG Tablet

TORGLIP D 5 MG Tablet, manufactured by Torrent Pharmaceuticals Ltd., is a combination medication designed to help manage blood sugar levels in adults with type 2 diabetes mellitus. It is typically prescribed when diet and exercise alone are insufficient to control blood sugar, or when blood sugar is poorly controlled on metformin monotherapy.

• Name:
  • Brand Name: TORGLIP D 5 MG Tablet
  • Common Name: Dapagliflozin and Vildagliptin Tablets
• Composition:
  • Each tablet contains Dapagliflozin 5 mg and Vildagliptin 100 mg.
• Uses:
  • Treatment of type 2 diabetes mellitus in adults.
  • To improve blood sugar control along with a healthy diet and regular exercise.
  • May help in reducing the risk of cardiovascular disease and worsening kidney disease in patients with type 2 diabetes.
• Dosage and Administration:
  • Take TORGLIP D 5 MG Tablet exactly as prescribed by your doctor.
  • It is usually taken orally once daily.
  • The tablet can be taken with or without food, but it is important to take it consistently at the same time each day to maintain stable blood sugar levels.
  • Swallow the tablet whole; do not crush, chew, or break it.
  • Do not stop taking the medication without consulting your doctor.
• Side Effects:
  • Common Side Effects: Hypoglycemia (low blood sugar, especially with other diabetes medications), urinary tract infections (UTIs), genital infections (e.g., vaginal inflammation, female genital mycotic infections, balanitis), headaches, dizziness, tremors, nausea, constipation, heartburn, joint pain (arthralgia), back pain, increased urination (polyuria), nasopharyngitis, fatigue, and dyslipidemia.
  • Serious Side Effects: Angioedema (swelling of face, throat, or tongue, trouble breathing), liver inflammation (yellowing of skin/eyes, dark urine, nausea, loss of appetite), and inflammation of the pancreas (severe stomach pain, nausea, vomiting). Dehydration may also occur.
• Precautions:
  • Inform your doctor if you have kidney or liver issues, heart problems, urinary tract infections, or are taking diuretics (water pills).
  • Not recommended for individuals with severe kidney impairment or end-stage renal disease.
  • Avoid excessive alcohol consumption as it may increase the risk of hypoglycemia.
  • Pregnant or breastfeeding women should consult their doctor before use.
  • Exercise caution when driving or operating machinery if you experience dizziness.
  • Regular monitoring of blood sugar levels is essential during treatment.
  • Interactions may occur with other anti-diabetic medications, diuretics, corticosteroids, thyroid hormones, and certain anticonvulsants.
• Storage:
  • Keep TORGLIP D 5 MG Tablet out of reach of children.
  • Store below 30°C, in a cool and dry place, away from moisture and direct sunlight.

What is TORGLIP D 5 MG TABLET used for?

TORGLIP D 5 MG TABLET is a combination medication primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus. It is typically prescribed when blood sugar is not adequately controlled with metformin alone, or when diet and exercise are insufficient. This medication helps improve blood sugar control by enhancing the body's proper use of insulin and can also assist in weight management and lowering blood pressure. Additionally, it may help in reducing the risk of heart complications and the worsening of kidney disease.

How does TORGLIP D 5 MG TABLET work?

TORGLIP D 5 MG TABLET contains two active ingredients: Dapagliflozin (5 mg) and Vildagliptin (100 mg).

• Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It works by blocking the reabsorption of glucose in the kidneys, leading to the excretion of excess sugar from the body through urine. This process helps lower blood sugar levels, particularly fasting glucose.
• Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It increases the levels of natural hormones (incretins) that stimulate the pancreas to release more insulin after meals and reduce the amount of glucagon (a hormone that raises blood sugar) produced by the liver. Together, these mechanisms provide a dual approach to effectively lower blood sugar levels.

What is the usual dosage of TORGLIP D 5 MG TABLET?

The dosage of TORGLIP D 5 MG TABLET is determined by your doctor and is individualized based on factors such as the severity of your diabetes, current blood sugar levels, other medications you may be taking, and your overall health. It is typically taken orally, once or twice daily. The tablet can be taken with or without food, but it is important to take it consistently at the same time each day to maintain stable blood sugar levels. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.

What are the possible side effects of TORGLIP D 5 MG TABLET?

Common side effects of TORGLIP D 5 MG TABLET can include:

• Hypoglycemia (low blood sugar), especially if taken with other diabetes medications.
• Urinary tract infections (UTIs) and genital fungal infections (such as vaginal inflammation or balanitis).
• Headache, dizziness, and tremors.
• Nausea, constipation, and heartburn.
• Swelling of hands, feet, or ankles (edema) and joint pain.
• Increased urination.
• Nasopharyngitis (inflammation of the nose and throat) and back pain.
• Dyslipidemia (abnormal amount of lipids in the blood).

Serious side effects requiring immediate medical attention include angioedema (swelling of the face, throat, or tongue, trouble swallowing and breathing), liver inflammation (yellowing of skin and eyes, nausea, loss of appetite, dark urine), and inflammation of the pancreas (persistent and severe stomach pain that may radiate to your back, nausea, vomiting). It is important to stay hydrated and maintain good hygiene to reduce the risk of infections.

Is TORGLIP D 5 MG TABLET safe during pregnancy or breastfeeding?

• Pregnancy: TORGLIP D 5 MG TABLET is generally not recommended during pregnancy, as there is limited information or no well-controlled human studies on its use in pregnant women. It should only be used if clearly needed and prescribed by a doctor, and if the potential benefits outweigh the risks. Some sources indicate it has dangerous side effects in pregnant women.
• Breastfeeding: It is generally not recommended during breastfeeding. It is not known whether the active ingredients are excreted in breast milk, and due to a lack of research, the side effects for breastfeeding women are not known. Always consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

Can TORGLIP D 5 MG TABLET be taken with other medications?

Yes, TORGLIP D 5 MG TABLET can interact with other medications. It is crucial to inform your doctor about all other medicines, herbs, or supplements you are currently taking or plan to take to avoid possible interactions.

• Increased risk of low blood sugar (hypoglycemia): When taken with other diabetes medications like insulin, sulphonylureas (e.g., glimepiride, glipizide), or repaglinide.
• Increased risk of dehydration and low blood pressure: When taken with diuretics (water pills) such as furosemide, hydrochlorothiazide, methyclothiazide, or trichlormethiazide.
• Increased risk of angioedema: When used with ACE inhibitors.
• Other potential interactions: Medicines used to reduce inflammation (e.g., prednisolone), manage underactive thyroid (e.g., levothyroxine), or manage fits (e.g., phenytoin or phenobarbital). Severe interactions have been noted with Aripiprazole and Gatifloxacin, and moderate interactions with Dexamethasone and Dopamine.

What precautions should be taken while taking TORGLIP D 5 MG TABLET?

Several precautions should be observed when taking TORGLIP D 5 MG TABLET:

• Do not stop taking the medication without consulting your doctor, as this can lead to increased blood sugar levels and serious complications.
• Regularly monitor your blood sugar levels as advised by your doctor.
• Inform your doctor if you have kidney or liver issues, urinary tract infections, a history of pancreatitis, or if you are taking diuretics.
• Avoid or limit excessive alcohol consumption, as it can increase the risk of side effects like hypoglycemia and lactic acidosis.
• Maintain good personal hygiene to help prevent genital fungal infections.
• If you experience dizziness, use caution when driving or operating machinery.
• The medication is not recommended for patients with moderate to severe renal impairment, those requiring dialysis, or children under 18 years of age.
• TORGLIP D 5 MG TABLET is part of a comprehensive diabetes management plan that includes a healthy diet, regular exercise, and weight reduction.

What happens if a dose of TORGLIP D 5 MG TABLET is missed?

If you miss a dose of TORGLIP D 5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should TORGLIP D 5 MG TABLET be stored?

TORGLIP D 5 MG TABLET should be stored in a cool and dry place, below 30°C (room temperature), away from direct sunlight, moisture, and heat. Keep it out of the sight and reach of children.