Ticagat 90 Mg Tablet (14 Tab)

TICAGAT 90 MG TABLET

TICAGAT 90 MG TABLET, manufactured by NATCO PHARMA LIMITED, is an antiplatelet medication designed to prevent the formation of harmful blood clots.

• Name:
  • Brand Name: TICAGAT 90 MG TABLET
  • Common Name: Ticagrelor
• Composition:
  • Each tablet contains 90.00 mg of Ticagrelor.
• Uses: TICAGAT is prescribed to reduce the risk of cardiovascular events, such as heart attack, stroke, and cardiovascular death. It is primarily used in patients with:
  • Acute Coronary Syndrome (ACS), including unstable angina or myocardial infarction (heart attack).
  • A history of myocardial infarction (MI).
  • Coronary Artery Disease (CAD) who are at high risk for a first MI or stroke.
  • Acute ischemic stroke or high-risk transient ischemic attack (TIA). It also helps prevent blood clots in patients who have undergone percutaneous coronary intervention (PCI) with stent placement.
• Dosage and Administration: TICAGAT is typically taken with a low-dose aspirin (75-100 mg daily).
  • Loading Dose: For patients with ACS, acute ischemic stroke, or TIA, the initial dose is usually 180 mg (two 90 mg tablets) taken as a single dose.
  • Maintenance Dose:
    • Following an ACS event or after a loading dose for stroke/TIA, the usual maintenance dose is 90 mg twice daily. This may be continued for up to one year for ACS, or up to 30 days for acute ischemic stroke/TIA.
    • After one year of maintenance therapy for ACS, the dose may be reduced to 60 mg twice daily, if recommended by a doctor.
  • The tablets can be taken with or without food. If unable to swallow whole, tablets may be crushed and mixed with water for immediate consumption.
• Side Effects:
  • Common Side Effects: Bleeding (e.g., nosebleeds, bruising, bleeding gums, heavier periods), shortness of breath (dyspnea), headache, dizziness, nausea, diarrhea, indigestion, constipation, rash, itching, and increased uric acid leading to joint pain (gout).
  • Serious Side Effects: Seek immediate medical attention if you experience severe, unexplained, or uncontrollable bleeding (e.g., bloody or tarry stools, coughing up blood, red or dark brown urine, vomit resembling coffee grounds), signs of a stroke (sudden numbness or weakness, difficulty speaking or understanding), or signs of an allergic reaction (e.g., swelling of the face, lips, tongue).
• Precautions:
  • TICAGAT carries a risk of serious bleeding. It should not be used in patients with active pathological bleeding or a history of intracranial hemorrhage.
  • Inform your doctor about any bleeding disorders, recent surgery (including dental procedures), stomach ulcers, or other conditions that increase bleeding risk. You may need to stop the medication at least 5 days before surgery.
  • Avoid aspirin doses exceeding 100 mg daily, as higher doses can reduce ticagrelor's effectiveness.
  • Do not stop taking TICAGAT abruptly, as this can increase the risk of heart attack or stroke.
  • Use with caution in older adults and avoid in severe liver disease.
  • TICAGAT can interact with certain medications, including strong CYP3A inhibitors (e.g., ketoconazole, clarithromycin) and inducers, certain cholesterol-lowering drugs (simvastatin, lovastatin at doses >40mg), digoxin, and other antiplatelet or anticoagulant agents. Consult your doctor or pharmacist about all medications and herbal products you are taking.
  • Alcohol consumption should be avoided as it can increase the risk of bleeding.
  • Not recommended for use in children.
• Storage: Store TICAGAT tablets in a closed container at room temperature, typically between 25°C (77°F), with excursions permitted to 15-30°C (59-86°F). Keep away from heat, moisture, and direct light, and prevent from freezing. Keep out of the reach of children.

TICAGAT 90 MG TABLET: Frequently Asked Questions

What is TICAGAT 90 MG TABLET used for?

TICAGAT 90 MG TABLET, containing the active ingredient Ticagrelor, is primarily used to reduce the risk of heart attack, stroke, and cardiovascular death in patients with acute coronary syndrome (ACS) or a history of heart attack. It is also prescribed to lower the risk of blood clots in patients with coronary artery disease (CAD) who are at high risk for such events, and in patients who have received stents to treat ACS. Additionally, it can reduce the risk of stroke in patients with acute ischemic stroke or high-risk transient ischemic attack (TIA).

How does TICAGAT 90 MG TABLET work?

TICAGAT Tablet is an antiplatelet medication, also known as a blood thinner. It works by preventing platelets (tiny blood cells) from sticking together and forming harmful blood clots in blood vessels. By doing so, it helps to reduce the risk of blockages that can lead to heart attacks or strokes.

What is the usual dosage of TICAGAT 90 MG TABLET?

For patients with acute coronary syndrome (ACS) or a history of heart attack, treatment typically begins with a 180 mg loading dose (often two 90 mg tablets). This is usually followed by a maintenance dose of 90 mg twice a day for the first year after an ACS event. After one year, your doctor may reduce the dose to 60 mg twice a day. For prevention of heart attack or stroke in patients with coronary artery disease (CAD), the usual dose is 60 mg twice a day. For acute ischemic stroke or TIA, a loading dose of 180 mg is followed by 90 mg twice a day for up to 30 days. TICAGAT is usually taken with a daily maintenance dose of aspirin (75-100 mg). It's crucial not to exceed 100 mg of aspirin daily as higher doses can decrease Ticagrelor's effectiveness.

What are the possible side effects of TICAGAT 90 MG TABLET?

Common side effects can include bleeding more easily than normal, shortness of breath (dyspnea), headaches, dizziness, nausea, indigestion, and diarrhea. Some individuals might experience an increased risk of gout due to elevated uric acid levels. Serious, though less common, side effects include severe bleeding (e.g., black or bloody stools, red or dark brown urine, coughing up blood), allergic reactions, and slow heartbeats. If you experience any severe or persistent side effects, contact your doctor immediately.

Is TICAGAT 90 MG TABLET safe during pregnancy or breastfeeding?

TICAGAT Tablet may pass into breast milk and could potentially cause side effects in a breastfed child. Its safety and effectiveness during pregnancy or breastfeeding have not been fully established. Therefore, it is generally not recommended during pregnancy or breastfeeding unless specifically advised by your doctor, who will weigh the potential benefits against the risks.

Can TICAGAT 90 MG TABLET be taken with other medications?

Ticagrelor can interact with several other medications. It's important to inform your doctor about all medicines you are taking, including over-the-counter drugs, vitamins, and herbal supplements. Taking maintenance doses of aspirin above 100 mg can reduce the effectiveness of Ticagrelor. Concomitant use with strong CYP3A inhibitors (e.g., certain antifungals, HIV drugs) can increase Ticagrelor levels, while strong CYP3A inducers (e.g., rifampin, some seizure drugs) can decrease its effectiveness. It can also increase the levels of certain cholesterol-lowering drugs (e.g., simvastatin, lovastatin) and digoxin, and increase the risk of bleeding when taken with other antiplatelets, anticoagulants, or NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen. Opioid medications may also affect its efficacy.

What precautions should be taken while taking TICAGAT 90 MG TABLET?

Due to the increased risk of bleeding, be cautious with activities that may cause injury and use care when shaving or brushing your teeth. It is crucial not to stop taking TICAGAT without consulting your doctor, as this can significantly increase your risk of heart attack or stroke. Inform all healthcare providers, including dentists, that you are taking this medication, especially before any surgery or medical procedures, as you may need to temporarily stop taking it at least 5 days prior. TICAGAT is contraindicated in patients with active pathological bleeding or a history of bleeding in the brain, and should be used with caution in patients with liver problems. Your doctor will monitor your progress with regular visits and may conduct blood tests.

What happens if a dose of TICAGAT 90 MG TABLET is missed?

If you miss a dose of TICAGAT, skip the missed dose and take your next dose at the regularly scheduled time. Do not take a double dose to make up for a forgotten one.

How should TICAGAT 90 MG TABLET be stored?

Store TICAGAT 90 MG TABLET in a closed container at room temperature, generally between 59°F and 86°F (15°C and 30°C). Keep it away from heat, moisture, and direct light. Do not freeze the medicine, and ensure it is kept out of the reach of children.