Cardace H 5 Tablet

CARDACE H 5 TABLET

CARDACE H 5 TABLET is a combination medication manufactured by Sanofi India Ltd., primarily used in the management of high blood pressure.

• Name:

  • Brand Name: CARDACE H 5 TABLET
  • Common Name: Ramipril and Hydrochlorothiazide tablets (combination)

• Composition: Each tablet contains:

  • Ramipril: 5 mg
  • Hydrochlorothiazide: 12.5 mg

• Uses: CARDACE H 5 TABLET is prescribed for:

  • Managing essential hypertension (high blood pressure).
  • Reducing the risk of cardiovascular events such as heart attacks and strokes.
  • Preventing kidney damage associated with high blood pressure.

• Dosage and Administration: The medicine should be taken orally as directed by a doctor. It can be taken with or without food, preferably once daily in the morning to avoid frequent nighttime urination. The dosage may vary based on individual factors and response to treatment. Do not crush, chew, or break the tablet.

• Side Effects: Common side effects may include:

  • Headache
  • Dizziness, light-headedness, or vertigo
  • Low blood pressure (hypotension)
  • Fatigue or tiredness
  • Dry cough
  • Nausea, indigestion, stomach pain, or diarrhea
  • Decreased sodium levels
  • Increased uric acid and blood lipid levels

  Serious side effects, though rare, warrant immediate medical attention:

  • Severe allergic reactions such as swelling of the face, lips, tongue, and/or throat (angioedema), which can lead to difficulty in breathing or swallowing.
  • Severe skin reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis).
  • Signs of lung problems (e.g., shortness of breath).

• Precautions:

  • Pregnancy and Breastfeeding: Not recommended during pregnancy as it may harm the unborn baby. It is also not recommended for breastfeeding women.
  • Alcohol: Limit or avoid alcohol consumption as it may enhance the blood pressure-lowering effect and cause dizziness.
  • Kidney and Liver Conditions: Use with caution in patients with kidney or liver problems. Dosage adjustments or close monitoring may be required. Not recommended for patients with severe kidney problems or those undergoing dialysis.
  • Diabetes and Gout: May affect blood sugar control and increase uric acid levels, requiring careful monitoring.
  • Driving and Operating Machinery: Avoid driving or operating heavy machinery if you experience dizziness or fatigue.
  • Drug Interactions: Inform your doctor about all current medications, including:
    • Lithium, Digoxin
    • NSAIDs (e.g., ibuprofen, naproxen, aspirin)
    • Potassium-sparing diuretics or potassium supplements, as they can increase potassium levels.
    • Other blood pressure-lowering medicines, including aliskiren or angiotensin II receptor antagonists, and sacubitril/valsartan.

• Storage: Store in a cool, dry place, ideally at room temperature (around 25°C or below 30°C). Protect from direct sunlight and moisture. Keep out of reach and sight of children.

CARDACE H 5 TABLET: Frequently Asked Questions

What is CARDACE H 5 TABLET used for?

CARDACE H 5 TABLET is primarily used to manage essential hypertension, also known as high blood pressure. This medication helps reduce the risk of serious complications associated with high blood pressure, such as heart attacks, strokes, and kidney damage. It is often prescribed to patients who have previously been treated with its individual active ingredients (ramipril or hydrochlorothiazide) at similar doses.

How does CARDACE H 5 TABLET work?

CARDACE H 5 TABLET contains two active ingredients: Ramipril (an ACE inhibitor) and Hydrochlorothiazide (a diuretic).

• Ramipril works by blocking the action of an enzyme called Angiotensin-converting enzyme (ACE), which is responsible for narrowing blood vessels. By inhibiting this enzyme, ramipril relaxes and widens the blood vessels, allowing blood to flow more smoothly and reducing the heart's workload.
• Hydrochlorothiazide is a diuretic, also known as a "water pill." It increases the production of urine, helping the body eliminate excess salt and water. This reduction in fluid volume in the blood vessels further helps to lower blood pressure. The combined action of these two ingredients effectively lowers high blood pressure.

What is the usual dosage of CARDACE H 5 TABLET?

The daily dose of CARDACE H 5 TABLET should be taken exactly as prescribed by your doctor. It is usually taken orally once daily, preferably in the morning to avoid frequent urination at night. The dosage can vary based on individual factors such as the severity of your condition and your response to the medication. Do not adjust your dosage without consulting your doctor.

What are the possible side effects of CARDACE H 5 TABLET?

Some common side effects may include dizziness, headache, low blood pressure (hypotension), fatigue, nausea, indigestion, taste changes, diarrhea, stomach pain, and a dry cough. Most of these side effects are usually temporary and resolve over time. However, if you experience any serious side effects or if symptoms worsen, it is important to consult your doctor.

Is CARDACE H 5 TABLET safe during pregnancy or breastfeeding?

CARDACE H 5 TABLET is generally not recommended for use during pregnancy as it may cause serious harm to the unborn baby. For breastfeeding mothers, CARDACE H 5 TABLET should also be avoided as it may pass into breast milk, and its effect on the baby is unknown. Always consult your doctor for safer alternatives if you are pregnant, planning to conceive, or breastfeeding.

Can CARDACE H 5 TABLET be taken with other medications?

It is crucial to inform your doctor about all the medicines, supplements, or herbal products you are currently taking to avoid potential drug interactions. CARDACE H 5 TABLET can interact with several medications, including:

• Lithium: May increase lithium levels, leading to toxicity.
• Digoxin: May increase the risk of side effects like nausea, vomiting, and irregular heartbeat.
• NSAIDs (e.g., ibuprofen, naproxen, aspirin): Can decrease the blood pressure-lowowering effect and/or increase the risk of kidney problems.
• Other blood pressure-lowering medicines (e.g., aliskiren, valsartan): May increase the risk of severe side effects like low blood pressure, kidney problems, and high potassium levels.
• Potassium-sparing diuretics (e.g., spironolactone, amiloride, triamterene) and potassium supplements: Can increase the risk of high potassium levels in the blood (hyperkalemia).
• Diabetes medications (e.g., insulin, oral hypoglycemics): May increase the blood sugar-lowering effects, raising the risk of hypoglycemia.

What precautions should be taken?

• Alcohol: Limit or avoid alcohol consumption while taking CARDACE H 5 TABLET, as it can enhance the blood pressure-lowering effect and cause dizziness.
• Driving and operating machinery: Be cautious while driving or operating heavy machinery, as this medicine may cause dizziness or fatigue.
• Kidney/Liver problems: Inform your doctor if you have kidney or liver problems, as the medication may need dose adjustment or may not be suitable.
• Allergies: Do not use CARDACE H 5 TABLET if you are allergic to ramipril, hydrochlorothiazide, or any other ingredient in the tablet.
• Diet: Avoid excessive salt intake and limit potassium-rich foods or supplements unless advised by your doctor, as this medicine can affect potassium levels.
• Dehydration: Drink plenty of fluids as CARDACE H 5 TABLET can cause dehydration due to its diuretic action.

What happens if a dose is missed?

If you miss a dose of CARDACE H 5 TABLET, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should CARDACE H 5 TABLET be stored?

Store CARDACE H 5 TABLET in a cool, dry place, ideally at room temperature (around 25°C or between 15°C to 30°C). Keep it in its original packaging, away from direct sunlight and moisture. Ensure the medicine is kept out of the reach and sight of children and pets.