Doxiflo M Tab

DOXIFLO M Tablet by LUPIN LTD

Name

• Brand Name: DOXIFLO M Tablet
• Manufacturer: Lupin Ltd.

Composition

DOXIFLO M Tablet contains a combination of two active ingredients:

• Doxofylline (400 mg)
• Montelukast (10 mg)

Uses

DOXIFLO M Tablet is primarily used for the management and prevention of various respiratory conditions and associated symptoms:

• Asthma: It helps manage asthma symptoms by relaxing the muscles around the airways, making breathing easier and preventing asthma attacks.
• Chronic Obstructive Pulmonary Disease (COPD): It aids in improving airflow and reducing inflammation in COPD, including chronic bronchitis and emphysema.
• Wheezing: Helps relieve the high-pitched whistling sound during breathing caused by narrowed airways.
• Chronic Bronchitis: Manages symptoms by reducing inflammation and opening up the airways.
• Allergy Symptoms: Also effective in relieving symptoms associated with allergies such as runny nose, sneezing, throat irritation, watery eyes, and congestion.

Note: This medicine is not intended for use during an acute asthma attack.

Dosage and Administration

• DOXIFLO M Tablet should be taken orally as prescribed by your doctor.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• It can be taken with or without food, but it is advisable to take it at the same time each day for consistent effectiveness.
• Do not exceed the recommended dosage.
• Avoid consuming with caffeine or chocolate, including foods like tea leaves and cocoa beans.

Side Effects

Common side effects may include:

• Headache
• Nausea, vomiting, stomach pain/discomfort, epigastric pain, indigestion, diarrhea
• Dizziness, sleepiness, insomnia (difficulty in sleeping)
• Irritation, altered mood, nervousness, agitation
• Increased heart rate (tachycardia)
• Fever, weakness, flu-like symptoms
• Cough, sneezing, runny nose, sore throat
• Skin rash, itching, swelling
• Uncommon serious effects include fits.

Consult your doctor if any side effects persist or worsen.

Precautions

• Allergy: Do not take if you are allergic to Doxofylline, Montelukast, or any other ingredients in the tablet.
• Heart Conditions: Use with caution if you have heart conditions such as arrhythmia, coronary artery disease, high blood pressure, low blood pressure, or a history of heart attack or heart failure.
• Liver Disease: Exercise caution in patients with liver disease; dose adjustment may be necessary in severe cases.
• Kidney Disease: Use with caution in patients with kidney disease; consult your doctor.
• Pregnancy: Consult your doctor if you are pregnant or planning to become pregnant, as there is limited information on its effects during pregnancy.
• Breastfeeding: This medicine is generally not recommended during breastfeeding as its components can pass into breast milk and may harm the baby.
• Driving and Operating Machinery: Doxiflo M Tablet may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how the medicine affects you.
• Alcohol: It is advisable to avoid or limit alcohol consumption while taking this medicine as it may increase the risk of side effects or worsen drowsiness.
• Other Medical Conditions: Inform your doctor if you have a history of seizures (fits), epilepsy, depression, phenylketonuria, hyperthyroidism (overactive thyroid), stomach ulcers, or viral infections.
• Drug Interactions: Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, to prevent potential interactions.
• Children: DOXIFLO M Tablet should be used in children above 15 years of age and adults.

Storage

• Store the medicine below 30°C (some sources indicate below 25°C) in a cool and dry place.
• Protect it from light and moisture.
• Keep the product out of reach and sight of children and pets.

DOXIFLO M TAB by LUPIN LTD is a medication combining Doxofylline and Montelukast, primarily used for managing various respiratory conditions.

What is DOXIFLO M TAB used for?

DOXIFLO M TAB is used to treat and prevent conditions such as asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema, bronchospasm, and allergic rhinitis. It helps in relieving symptoms like chest tightness, wheezing, coughing, and shortness of breath.

How does DOXIFLO M TAB work?

This medicine contains two active ingredients: Doxofylline and Montelukast. Doxofylline is a bronchodilator that works by relaxing the muscles and widening the airways in the lungs, making breathing easier. Montelukast is a leukotriene receptor antagonist that blocks certain chemical messengers (leukotrienes) that cause inflammation and swelling in the airways, thereby reducing inflammation and preventing bronchoconstriction.

What is the usual dosage for DOXIFLO M TAB?

The usual dosage is typically one tablet daily, or as directed by your doctor. It is often recommended to take it in the evening, with or without food. You should swallow the tablet whole with water, without chewing or crushing it. It's crucial not to exceed the recommended dose and to follow your doctor's instructions.

What are the possible side effects of DOXIFLO M TAB?

Common side effects may include fever, nausea, vomiting, stomach pain, headache, insomnia (difficulty sleeping), irritation, sore throat, and an increased heart rate. Other possible side effects include dizziness, fatigue, skin rash, palpitations, and flu-like symptoms. Rarely, mood and behavior changes like anxiety, aggression, depression, or suicidal thoughts may occur with Montelukast. If side effects persist or worsen, consult your doctor.

Is DOXIFLO M TAB safe during pregnancy or breastfeeding?

It is advised to consult your doctor before using DOXIFLO M TAB during pregnancy or breastfeeding, as its safety in these situations has not been fully established for the combination. While Montelukast alone may be considered during pregnancy if clearly needed and with proper asthma control, and passes into breast milk in tiny amounts without known side effects, caution is recommended for the combination. Your doctor will weigh the potential benefits against the risks.

Can DOXIFLO M TAB be taken with other medications?

DOXIFLO M TAB can interact with several medications. Inform your doctor about all medicines you are taking, including those for gout (e.g., allopurinol), stomach ulcers (e.g., cimetidine), bacterial infections (e.g., erythromycin, clindamycin), fits (e.g., phenytoin), other asthma medicines (e.g., salbutamol, theophylline), and the influenza vaccine. Limiting alcohol intake is also advised as it may increase side effects like drowsiness.

What precautions should be taken while using DOXIFLO M TAB?

DOXIFLO M TAB is not intended for use during an acute asthma attack; a separate rescue inhaler should be used for sudden breathing problems. You should inform your doctor if you have heart, liver, kidney, or lung diseases, neuropsychiatric disorders (like seizures or depression), phenylketonuria, hyperthyroidism, high blood pressure, stomach ulcers, or viral infections. Do not stop taking the medicine abruptly without consulting your doctor, even if you feel better. This medication may cause drowsiness or dizziness, so be cautious when driving or operating machinery.

What happens if a dose of DOXIFLO M TAB is missed?

If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should DOXIFLO M TAB be stored?

Store DOXIFLO M TAB at room temperature, in a cool and dry place. Keep it away from direct sunlight and moisture, and out of the reach of children and pets.