Biggaba Nt Tab

BIGGABA NT TAB

BIGGABA NT TAB is a prescription medication manufactured by Mankind Pharma Ltd., formulated to manage neuropathic pain and its associated symptoms.

• Name:

  • Brand Name: BIGGABA NT TAB, Biggaba NT 75mg/10mg Tablet SR
  • Manufacturer: Mankind Pharma Ltd.

• Composition:

  • Each tablet typically contains a combination of:
    • Pregabalin: 75mg (an anti-convulsant and analgesic)
    • Nortriptyline: 10mg (a tricyclic antidepressant) Pregabalin works by modulating calcium channels in nerve cells to reduce pain signals, while Nortriptyline increases levels of chemical messengers (serotonin and noradrenaline) in the brain to stop the movement of pain signals.

• Uses: BIGGABA NT TAB is primarily used for the management of neuropathic pain, which is chronic pain caused by nerve damage. This includes conditions such as:

  • Diabetic peripheral neuropathy
  • Postherpetic neuralgia (nerve pain after shingles)
  • Spinal cord injury-related pain It also helps in alleviating associated symptoms like burning, shooting, stabbing pain, numbness, and can improve sleep disturbances and mood in some patients. It may also be used in combination with other medicines to treat certain types of seizures.

• Dosage and Administration:

  • Always take BIGGABA NT TAB exactly as directed by your physician.
  • It can be taken with or without food, preferably at bedtime, as it can cause drowsiness.
  • Swallow the tablet whole; do not crush or chew it.
  • Take the medicine at the same time each day to maintain a consistent level in the blood.
  • The correct dose and duration will be determined by your doctor based on your age, body weight, and medical condition.
  • Do not stop taking this medication suddenly without consulting your doctor, as abrupt discontinuation can lead to withdrawal symptoms such as anxiety, insomnia, nausea, headache, and depression. A gradual dose reduction is typically required.

• Side Effects: Common side effects may include:

  • Dizziness, drowsiness, headache
  • Nausea, vomiting, constipation, dry mouth
  • Blurred vision
  • Increased appetite, weight gain
  • Peripheral edema (swelling of hands and feet)
  • Orthostatic hypotension (sudden drop in blood pressure upon standing)
  • Difficulty concentrating, memory impairment
  • Tremor, uncoordinated body movements Serious side effects, though rare, can include a swollen face or tongue, or skin redness with blisters or peeling, which require immediate medical attention. The medicine can also increase the risk of suicidal thoughts and behavior in some individuals.

• Precautions:

  • Pregnancy and Breastfeeding: Not recommended for use in pregnant or breastfeeding women unless specifically advised by a doctor.
  • Children: Strictly not recommended for children below 6 years of age, and safety for older children has not been established.
  • Elderly: Use with caution in patients aged 65 years or above, requiring careful monitoring and dose titration.
  • Driving and Operating Machinery: Avoid activities requiring mental alertness, such as driving or operating heavy machinery, if you experience dizziness, sleepiness, or blurred vision.
  • Alcohol: Avoid consuming alcohol, as it can intensify side effects like dizziness and sleepiness, and may lead to serious adverse effects.
  • Medical Conditions: Inform your doctor if you have severe heart or kidney disease, liver problems, bipolar syndrome, seizure disorders, or if you have recently taken MAO inhibitors.
  • Drug Interactions: Inform your doctor about all other medications, supplements, and herbal remedies you are taking, especially other antidepressants, antipsychotics, medicines for blood pressure or heart conditions, antiepileptics, cimetidine, oxycodone, and certain cough-cold medicines. Avoid taking antacids within 2 hours of BIGGABA NT TAB. Grapefruit and grapefruit juice may also interact.
  • Sun Sensitivity: This medication can make you more prone to sunburns; wear protective clothing and use sunscreen when outdoors.

• Storage:

  • Store BIGGABA NT TAB below 30°C.
  • Keep it in a cool, dry place, away from direct sunlight and moisture.
  • Keep out of the reach of children and pets.

Here are frequently asked questions about BIGGABA NT TAB by MANKIND - PANACEA NEO:

What is BIGGABA NT TAB used for?

BIGGABA NT TAB is used for the management of neuropathic pain. This is a type of chronic pain caused by damage or disease affecting the somatosensory nervous system, often associated with conditions like diabetic peripheral neuropathy, postherpetic neuralgia, and spinal cord injury. It aims to reduce shooting, burning, or stabbing pain, tingling, numbness, and also helps with associated symptoms like mood changes, sleep problems, and tiredness.

How does BIGGABA NT TAB work?

BIGGABA NT TAB is a combination medicine containing Pregabalin and Nortriptyline. Pregabalin is an anti-convulsant that works by reducing the release of a chemical (neurotransmitter) in the brain responsible for the sensation of pain. Nortriptyline is a tricyclic antidepressant that increases the levels of certain chemical messengers (serotonin and noradrenaline) in the brain, thereby reducing pain messages arriving in the brain and helping to stabilize mood.

What is the usual dosage of BIGGABA NT TAB?

BIGGABA NT TAB should be taken exactly as directed by your physician. Your doctor will determine the correct dose and duration based on your age, body weight, and medical condition. It can be taken with or without food, preferably at bedtime, and at the same time each day to maintain a consistent level of medicine in the blood. Do not stop taking it without consulting your doctor.

What are the possible side effects of BIGGABA NT TAB?

Common side effects of BIGGABA NT TAB include dizziness, sleepiness/drowsiness, dry mouth, blurred vision, constipation, nausea, vomiting, headache, increased appetite, weight gain, and peripheral edema (swelling of lower legs and hands). Other possible side effects can include insomnia, decreased sex drive, erectile dysfunction, memory impairment, tremors, and a stuffy nose. If any side effects worsen or persist, consult your doctor.

Is BIGGABA NT TAB safe during pregnancy or breastfeeding?

BIGGABA NT TAB is generally not recommended for use in pregnant women or women of childbearing age unless advised by a doctor, as there is limited information on its safety and potential harm to the fetus. Similarly, it is not recommended for use in breastfeeding women because it may excrete into breast milk and could harm the newborn baby. Your doctor may advise you to either stop breastfeeding or discontinue the medicine.

Can BIGGABA NT TAB be taken with other medications?

Before taking BIGGABA NT TAB, inform your doctor about all other medicines, supplements, or herbal products you are currently taking or plan to take to avoid possible interactions. Specific interactions exist with other antidepressants (e.g., fluoxetine, sertraline), antipsychotics, sympathomimetic agents (e.g., ephedrine), and medicines for high blood pressure. It is also advised to avoid alcohol as it can increase dizziness and sleepiness.

What precautions should be taken while using BIGGABA NT TAB?

Avoid consuming alcohol as it can increase drowsiness and sleepiness. Do not drive or operate machinery if you experience dizziness, drowsiness, or blurred vision. Inform your doctor if you have heart problems, severe liver or kidney disease, diabetes, high blood pressure, bipolar syndrome, or a history of seizures. Do not stop the medicine abruptly, as it can lead to withdrawal symptoms. This medicine may increase the risk of suicidal thoughts, so seek medical advice if such signs emerge.

What happens if a dose of BIGGABA NT TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to compensate for the missed one, as this may increase the risk of side effects.

How should BIGGABA NT TAB be stored?

BIGGABA NT TAB should be stored in a cool and dry place, below 30°C, away from direct sunlight and moisture. Keep it out of sight and reach of children.