Metolar Am 50 Tablet

METOLAR AM 50 TABLET

Metolar AM 50 Tablet is a fixed-dose combination medication manufactured by Cipla Health Ltd..

Composition Each tablet contains two active ingredients:

• Amlodipine: 5 mg (a calcium channel blocker)
• Metoprolol Succinate: 50 mg (an extended-release beta-1 selective adrenoceptor blocking agent)

Uses Metolar AM 50 Tablet is primarily used to manage and treat:

• Hypertension (high blood pressure): It helps relax blood vessels and reduce heart rate, making it easier for the heart to pump blood throughout the body. This reduces the risk of serious cardiovascular events such as strokes and heart attacks.
• Angina pectoris (heart-related chest pain): It helps improve blood flow to the heart and reduces myocardial oxygen demand, thereby lessening the frequency of angina attacks and enhancing exercise tolerance.
• It is also used for abnormal heart rhythms and chronic (long-term) heart failure.

Dosage and Administration The dosage should be individualized and taken as advised by a doctor. Typically, the recommended initial dose is one tablet once daily.

• Swallow the tablet whole with a glass of water; do not break, crush, or chew it.
• It can be taken with or without food, but it is best to take it at the same time each day for optimal effectiveness.
• Do not exceed the recommended dose or stop the medicine abruptly without consulting your doctor, as this can worsen the condition.

Side Effects Common side effects may include:

• Dizziness
• Fatigue/Tiredness
• Nausea
• Headache
• Edema (swelling), particularly ankle swelling
• Slow heart rate (bradycardia)
• Abdominal pain or discomfort
• Diarrhoea
• Low blood pressure

Serious side effects are less common, but if any symptoms persist or worsen, consult a doctor.

Precautions

• Pregnancy and Breastfeeding: Caution is advised. Consult your doctor before using if pregnant or breastfeeding.
• Alcohol: Avoid or limit alcohol consumption as it may increase the risk of dizziness, low blood pressure, and interfere with the extended-release properties of metoprolol succinate.
• Driving and Operating Machinery: Metolar AM 50 Tablet may cause dizziness or tiredness, affecting mental focus. Avoid driving or operating machinery until you understand how the medicine affects you.
• Liver/Kidney Issues: Use with caution in patients with liver disease due to extensive hepatic metabolism of both active ingredients. For kidney health concerns, consult your doctor.
• Drug Interactions: Inform your doctor about all other medications, including over-the-counter drugs and supplements, to avoid potential interactions. Interactions can occur with CYP3A4 inhibitors (e.g., ketoconazole), CYP2D6 inhibitors (e.g., fluoxetine), cardiac glycosides (e.g., digoxin), NSAIDs (e.g., ibuprofen), and certain calcium channel blockers (e.g., verapamil, diltiazem).
• Diet: Avoid potassium-rich foods or supplements as the medicine might raise potassium levels in the blood.
• Monitoring: Regular monitoring of blood pressure, kidney function, and electrolyte levels may be required during treatment.

Storage Store Metolar AM 50 Tablet at room temperature, ideally between 20-25°C, or below 30°C. Keep it away from direct light and moisture to maintain its effectiveness. Always keep this medicine out of reach of children and pets. Ensure to use the medicine before its expiration date.

Here are frequently asked questions about METOLAR AM 50 TABLET by CIPLA HEALTH LTD:

What is METOLAR AM 50 Tablet used for?

METOLAR AM 50 Tablet is primarily used to treat hypertension (high blood pressure) and heart-related chest pain (angina). It also helps manage abnormal heart rhythms and chronic (long-term) heart failure, reducing the risk of heart attack or stroke.

How does METOLAR AM 50 Tablet work?

METOLAR AM 50 Tablet is a combination medicine containing Amlodipine and Metoprolol. Amlodipine, a calcium channel blocker, relaxes and widens blood vessels by blocking calcium entry into heart and vessel walls. Metoprolol, a beta-blocker, slows down the heart rate and relaxes blood vessels by blocking certain natural substances in the body. Together, they lower high blood pressure and improve blood flow, reducing strain on the heart.

What is the usual dosage for METOLAR AM 50 Tablet?

The recommended initial dose is typically one tablet of METOLAR AM-50 once daily. Depending on the patient's response and tolerability, the dose may be adjusted or increased to two tablets once daily by a doctor. Dosage should be individualized, especially for elderly patients, those who are fragile, or individuals with liver impairment.

What are the possible side effects of METOLAR AM 50 Tablet?

Common side effects may include headache, dizziness, fatigue, nausea, abdominal pain, diarrhea, slow heart rate, and breathlessness. Other potential side effects include ankle swelling (edema), flushing, constipation, and sleepiness. Most side effects are temporary and resolve over time, but if they persist or worsen, consult your doctor.

Is METOLAR AM 50 Tablet safe during pregnancy or breastfeeding?

METOLAR AM 50 Tablet is generally not recommended during pregnancy unless your doctor considers it essential, weighing the potential benefits against risks to the fetus. If you are breastfeeding, it is recommended that nursing be discontinued while taking this medication as Metoprolol is excreted in breast milk, and it is unknown if amlodipine is as well.

Can METOLAR AM 50 Tablet be taken with other medications?

METOLAR AM 50 Tablet can interact with various medications. Inform your doctor about all medicines, supplements, or herbal remedies you are taking. Interactions can occur with drugs like catecholamine-depleting agents (e.g., reserpine), CYP2D6 inhibitors (e.g., quinidine, fluoxetine), CYP3A4 inducers, digitalis glycosides, clonidine, diltiazem, verapamil, NSAIDs (e.g., ibuprofen), and certain antidepressants. Co-administration with some medications may increase side effects or alter the effectiveness of METOLAR AM 50 Tablet.

What precautions should be taken while using METOLAR AM 50 Tablet?

Do not stop taking METOLAR AM 50 Tablet abruptly without consulting your doctor, as this can lead to a sudden increase in blood pressure, chest pain, or a heart attack. Avoid alcohol consumption as it can increase the risk of dizziness and low blood pressure. Inform your doctor if you have asthma, severe breathing problems, heart conditions (such as heart failure or heart block), liver or kidney problems, diabetes, or pheochromocytoma. This medicine may cause drowsiness, so exercise caution when driving or operating machinery. Avoid potassium-rich foods or supplements as this medication might raise potassium levels.

What happens if a dose of METOLAR AM 50 Tablet is missed?

If you miss a dose of METOLAR AM 50 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should METOLAR AM 50 Tablet be stored?

METOLAR AM 50 Tablet should be stored in a cool and dry place, away from direct sunlight, moisture, and heat. Keep it out of sight and reach of children.