Zeblong 16 Mg Tablet (10 Tab)

ZEBLONG 16 MG TABLET (10 TAB) by IPCA LABORATORIES LTD.

Name

Brand Name: ZEBLONG 16 MG TABLET Common Name: Azelnidipine (as the active ingredient)

Composition

ZEBLONG 16 MG TABLET contains 16 mg of Azelnidipine. It belongs to the class of dihydropyridine calcium channel blockers.

Uses

This medication is primarily used for the management of high blood pressure (hypertension), including stage-I and stage-II hypertension. It works by relaxing and widening blood vessels, thereby lowering blood pressure and reducing the workload on the heart. This action helps in the prevention of serious cardiovascular events such as heart attacks and strokes. It may also be used to manage chest pain (angina), alleviate coronary artery disease, assist in stabilizing heart failure, and balance certain types of irregular heartbeat (arrhythmia).

Dosage and Administration

ZEBLONG 16 MG TABLET should be taken orally, exactly as prescribed by your doctor. It is typically administered once daily at a consistent time each day, with or without food, to maintain steady medication levels in the bloodstream. The tablet should be swallowed whole with a glass of water and not chewed, crushed, or broken. Do not stop taking the medicine without consulting your doctor, even if you feel well, as abruptly discontinuing it can lead to a dangerous elevation in blood pressure.

Side Effects

Common side effects include:

• Headache
• Dizziness, light-headedness, or drowsiness
• Nausea, constipation, abdominal pain, or diarrhea
• Edema (swelling, particularly in the feet or ankles)
• Flushing (sudden reddening of the face, neck, or upper chest)
• Itching or rash
• Fatigue or abnormal sensations
• Frequent urination

Serious side effects, though rarely seen, may include:

• Liver problems (e.g., yellowing of skin, nausea, vomiting, loss of appetite)
• Pancreatitis (severe stomach pain)
• Recurrent chest pain indicative of a heart attack
• Cardiac arrest or heart rhythm disorders (sinus block, bradycardia)

Consult a healthcare professional if any side effects persist or worsen.

Precautions

Inform your doctor about any pre-existing liver, heart, or kidney conditions before starting treatment.

• Pregnancy and Breastfeeding: ZEBLONG 16 MG TABLET is not recommended for use in pregnant or breastfeeding women. Seek medical advice before use.
• Alcohol: Exercise caution or limit alcohol consumption as it may increase the risk of side effects.
• Grapefruit: Avoid consuming grapefruit or grapefruit juice, as it may increase the risk of low blood pressure.
• Driving: This medicine may cause dizziness or drowsiness, affecting the ability to drive or operate heavy machinery.
• Drug Interactions: Inform your doctor about all other medications you are taking, especially other antihypertensives, anti-diabetic medicines, anti-coagulants (like warfarin), medicines for fungal or HIV infections, cimetidine, imatinib, certain antibiotics (erythromycin, clarithromycin, rifampicin), cyclosporine, medicines for anxiety/insomnia, phenytoin, phenobarbital, hormonal contraceptives, and digoxin.

Storage

Store ZEBLONG 16 MG TABLET in a cool and dry place, below 25°C or 30°C. Protect it from extreme heat, light, and moisture. Keep this medicine out of sight and reach of children and ensure it is used before its expiry date.

What is ZEBLONG 16 MG TABLET used for?

ZEBLONG 16 MG TABLET is primarily prescribed for the management of high blood pressure, also known as hypertension, including both stage-I and stage-II hypertension. It helps prevent serious cardiovascular events such as heart attacks and strokes. Additionally, it can be used to manage chest pain (angina), alleviate coronary artery disease, assist in stabilizing heart failure, and regulate certain types of irregular heartbeats (arrhythmia).

How does ZEBLONG 16 MG TABLET work?

This medicine contains azelnidipine, which belongs to a class of drugs called calcium channel blockers. ZEBLONG 16 MG TABLET works by blocking the movement of calcium into the cells of the heart and blood vessels. This action relaxes and widens the blood vessels, which reduces the pressure within them. As a result, blood flows more easily, lowering blood pressure and reducing the workload on the heart.

What is the usual dosage for ZEBLONG 16 MG TABLET?

For adults, the typical starting dose is 8 mg once daily, which may be adjusted by your doctor based on your individual response and how well you tolerate the medication. The maximum recommended daily dose is 16 mg. It is generally advised to take the tablet once daily, at the same time each day, to maintain consistent medication levels in your body. The tablet should be swallowed whole with a glass of water, and it can be taken with or without food.

What are the possible side effects of ZEBLONG 16 MG TABLET?

Common side effects may include headache, dizziness, fatigue, nausea, constipation, abdominal pain, diarrhea, frequent urination, itching, drowsiness, flushing, and swelling in the feet or ankles (edema). Though rarely seen, more serious side effects can occur, such as liver problems (indicated by yellowing of skin, nausea, vomiting, and loss of appetite), pancreatitis (severe stomach pain, nausea, and vomiting), and recurrent chest pain, which could be a sign of a heart attack.

Is ZEBLONG 16 MG TABLET safe during pregnancy or breastfeeding?

ZEBLONG 16 MG TABLET is generally not recommended for use during pregnancy or for women who have a possibility to conceive, as it may negatively impact the developing baby. It is also not advised for breastfeeding mothers because the medication can pass into breast milk. Always consult your doctor for medical advice before using this medication if you are pregnant, planning to become pregnant, or are breastfeeding.

Can ZEBLONG 16 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all prescription, over-the-counter, and herbal medications, as well as any supplements you are currently taking. ZEBLONG 16 MG TABLET can interact with other blood pressure-lowering medications, anti-diabetic drugs (potentially affecting blood sugar levels), and anticoagulants like warfarin, which could increase the risk of bleeding. Interactions may also occur with certain medications for fungal infections, HIV, stomach problems (e.g., cimetidine), cancer (e.g., imatinib), bacterial infections, immunosuppressants (e.g., cyclosporine), anxiety/insomnia, seizures (e.g., phenytoin, phenobarbital), hormones (e.g., estradiol, norethindrone), heart conditions (e.g., digoxin), and high cholesterol (e.g., simvastatin).

What precautions should be taken while using ZEBLONG 16 MG TABLET?

Before starting treatment, it is important to inform your doctor if you have any pre-existing liver, heart, or kidney conditions. You should avoid consuming grapefruit or grapefruit juice, as it can interfere with the medication's absorption and increase the risk of low blood pressure. Alcohol consumption should be avoided or limited, as it may exacerbate side effects. Regular monitoring of your blood pressure is necessary to ensure the medication's effectiveness. Do not stop taking ZEBLONG 16 MG TABLET without consulting your doctor, even if you feel well, as abruptly discontinuing the medication can worsen your condition.

What happens if a dose of ZEBLONG 16 MG TABLET is missed?

If you miss a dose of ZEBLONG 16 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should ZEBLONG 16 MG TABLET be stored?

ZEBLONG 16 MG TABLET should always be stored in a cool and dry place, typically below 25°C or 30°C. It should be protected from light and moisture and kept out of the reach and sight of children.