Brutaflam 90 Tablet

BRUTAFLAM 90 TABLET

Brutaflam 90 Tablet, manufactured by Mankind Pharma Ltd, is a pain-relieving medication used to alleviate moderate pain, stiffness, and swelling. It is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class, specifically a selective cyclooxygenase-2 (COX-2) inhibitor.

Composition

The active ingredient in Brutaflam 90 Tablet is Etoricoxib 90 mg. Etoricoxib works by blocking the release of certain chemical messengers, prostaglandins, which are responsible for pain and inflammation in the body.

Uses

Brutaflam 90 Tablet is prescribed for adults and adolescents 16 years of age and older for the symptomatic relief of various conditions affecting joints and muscles, including:

• Osteoarthritis (OA)
• Rheumatoid Arthritis (RA)
• Ankylosing Spondylitis
• Acute Gouty Arthritis It is also used for the short-term treatment of moderate pain after dental surgery.

Dosage and Administration

Brutaflam 90 Tablet can be taken with or without food, as advised by your doctor. Swallow the tablet whole with a glass of water; do not crush or chew it. The dose and duration of treatment depend on the condition being treated and the patient's response. For dental pain, it is typically limited to a maximum of 3 days. It is important not to exceed the recommended dose or use it for longer than prescribed, as this can increase the risk of side effects.

Side Effects

Common side effects may include:

• Stomach pain
• Edema (swelling)
• Dizziness
• Headache
• Increased blood pressure
• Nausea
• Diarrhea or constipation
• Indigestion (dyspepsia)

Serious side effects, though less common, can include gastrointestinal bleeding, ulcers, and liver problems. Inform your doctor if any side effects persist or worsen.

Precautions

• Allergies: Do not take if allergic to etoricoxib or other NSAIDs.
• Cardiovascular Risk: Use with caution if you have a history of heart failure, high blood pressure, or other heart-related conditions, as it may increase the risk of heart attack or stroke, especially with higher doses and prolonged use. Regularly monitor blood pressure.
• Gastrointestinal Issues: Avoid if you have a history of stomach ulcers, bleeding in the stomach/intestine, or inflammatory bowel disease.
• Liver/Kidney Disease: Use with caution and inform your doctor if you have liver or kidney problems.
• Pregnancy and Breastfeeding: Brutaflam 90 Tablet is not recommended during pregnancy, especially in the third trimester, and caution is advised during breastfeeding. Consult your doctor.
• Alcohol: Avoid alcohol consumption as it may increase the risk of stomach discomfort and excessive drowsiness.
• Driving: May cause dizziness or fatigue, so exercise caution when driving or operating machinery.

Storage

Store Brutaflam 90 Tablet in a cool and dry place, away from direct sunlight, moisture, and excessive heat. Keep out of reach and sight of children.## BRUTAFLAM 90 TABLET

Brutaflam 90 Tablet, manufactured by Mankind Pharma Ltd, is a pain-relieving medicine used to alleviate moderate pain, stiffness, and swelling. It is a non-steroidal anti-inflammatory drug (NSAID) belonging to the coxib class, specifically a selective cyclooxygenase-2 (COX-2) inhibitor.

Composition

The active ingredient in Brutaflam 90 Tablet is Etoricoxib 90 mg. This compound works by selectively blocking the release of certain chemical messengers, prostaglandins, which are responsible for pain and inflammation in the body.

Uses

Brutaflam 90 Tablet is prescribed for adults and adolescents 16 years of age and older for the symptomatic relief of various inflammatory conditions affecting joints and muscles, including:

• Osteoarthritis (OA)
• Rheumatoid Arthritis (RA)
• Ankylosing Spondylitis
• Acute Gouty Arthritis Additionally, it is used for the short-term treatment of moderate pain following dental surgery.

Dosage and Administration

Brutaflam 90 Tablet can be taken with or without food, as advised by a healthcare professional. The tablet should be swallowed whole with a glass of water and not crushed or chewed. The dosage and duration of therapy are determined by the doctor based on the patient's age, weight, and specific medical condition. For dental pain, treatment is typically limited to a maximum of 3 days. It is crucial to adhere to the prescribed dosage and not exceed it, as this can increase the risk of adverse effects.

Side Effects

Common side effects associated with Brutaflam 90 Tablet include:

• Stomach pain
• Edema (swelling)
• Dizziness
• Headache
• Increased blood pressure
• Nausea
• Diarrhea or constipation
• Indigestion (dyspepsia)

More serious but less common side effects can include gastrointestinal bleeding, ulcers, and liver problems. Patients should consult their doctor if any side effects are persistent or worsen.

Precautions

• Allergies: This medicine is contraindicated in patients with known allergies to etoricoxib or any other components of the medicine, as well as those with a history of allergies to other painkillers (NSAIDs).
• Cardiovascular Risk: Exercise caution in patients with a history of heart failure, high blood pressure, diabetes, or high cholesterol, as Brutaflam 90 Tablet may increase the risk of cardiovascular events like heart attack or stroke, especially with higher doses and prolonged use. Regular blood pressure monitoring is recommended during treatment.
• Gastrointestinal Issues: Brutaflam 90 Tablet should be avoided in patients with a history of stomach ulcers, bleeding in the stomach or intestines, or inflammatory bowel disease.
• Hepatic and Renal Impairment: Patients with liver or kidney disease should use this medication with caution, and their doctor should be informed of such conditions.
• Pregnancy and Breastfeeding: Brutaflam 90 Tablet is generally not recommended during pregnancy, particularly in the third trimester, and caution is advised for breastfeeding mothers. Consultation with a doctor is essential.
• Alcohol Consumption: It is advisable to avoid alcohol while taking this medicine, as it can increase the risk of stomach discomfort and excessive drowsiness.
• Alertness: The medicine may cause dizziness or fatigue, therefore, caution should be exercised when driving or operating heavy machinery until the individual's reaction to the medication is known.

Storage

Brutaflam 90 Tablet should be stored in a cool and dry place, protected from direct sunlight, moisture, and excessive heat, at a temperature below 30°C. Keep the medicine out of the reach and sight of children.

Brutaflam 90 Tablet is a non-steroidal anti-inflammatory drug (NSAID) containing etoricoxib, used to relieve pain and inflammation in various conditions.

What is Brutaflam 90 Tablet used for?

Brutaflam 90 Tablet is primarily used to relieve pain, swelling, and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout in individuals aged 16 years and older. It is also prescribed for the short-term treatment of moderate pain following dental surgery.

How does Brutaflam 90 Tablet work?

Brutaflam 90 Tablet contains etoricoxib, which is a selective cyclooxygenase-2 (COX-2) inhibitor. It works by blocking the production of chemical messengers called prostaglandins, which are responsible for causing pain, swelling, and inflammation in the body. By inhibiting COX-2, Brutaflam helps reduce these symptoms.

What is the usual dosage for Brutaflam 90 Tablet?

The dosage of Brutaflam 90 Tablet is determined by your doctor based on your condition and response to treatment. It is usually taken once daily, with or without food. For conditions like ankylosing spondylitis, the recommended dose is often 60 mg once daily, which may be increased to 90 mg once daily if needed. For moderate pain after dental surgery, the recommended dose is 90 mg once daily, limited to a maximum of 3 days. It's crucial not to exceed the prescribed dose or duration to avoid increased risks of side effects.

What are the possible side effects of Brutaflam 90 Tablet?

Common side effects can include stomach pain, indigestion (dyspepsia), headache, dizziness, swelling of the legs (edema), increased blood pressure, flatulence, heartburn, nausea, vomiting, constipation, diarrhea, and flu-like symptoms. More serious but less common side effects can include gastrointestinal bleeding, ulcers, and liver problems. If you experience any severe or persistent side effects, you should consult your doctor.

Is Brutaflam 90 Tablet safe during pregnancy or breastfeeding?

Brutaflam 90 Tablet is generally not recommended during pregnancy, especially in the third trimester, as it may have toxic effects on the fetus and can cause complications like uterine inertia and premature closure of the ductus arteriosus. For breastfeeding mothers, it should be used with caution and only if prescribed by a doctor, as it is not known whether etoricoxib passes into breast milk. It is also not recommended for women attempting to conceive.

Can Brutaflam 90 Tablet be taken with other medications?

Brutaflam 90 Tablet can interact with other medications. It is important to inform your doctor about all medicines you are taking, including over-the-counter drugs and herbal supplements. For example, high doses of aspirin (above 300mg) or other NSAIDs should generally not be taken with Brutaflam 90 Tablet, as it can increase the risk of stomach ulcers. However, low-dose aspirin for heart disease can be taken under a doctor's guidance. It may also interact with anticoagulants like warfarin, diuretics, ACE inhibitors, angiotensin II antagonists, methotrexate, ciclosporin, tacrolimus, and certain oral contraceptives.

What precautions should be taken with Brutaflam 90 Tablet?

Before taking Brutaflam 90 Tablet, inform your doctor if you have a history of stomach ulcers or bleeding, high blood pressure (especially if uncontrolled), heart failure, liver disease, kidney disease, diabetes, or high cholesterol. It should not be used in individuals under 16 years of age. Avoid alcohol consumption as it may increase the risk of stomach discomfort or bleeding and can cause excessive drowsiness. Do not drive or operate heavy machinery if you experience dizziness or sleepiness. Brutaflam can mask fever, which is a sign of infection, so inform your doctor if you have an infection.

What happens if a dose of Brutaflam 90 Tablet is missed?

If you miss a dose of Brutaflam 90 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Brutaflam 90 Tablet be stored?

Brutaflam 90 Tablet should be stored in a cool and dry place, protected from direct sunlight, moisture, and excessive heat. Keep the medicine out of reach and sight of children to prevent accidental ingestion.