Clomipure 100

CLOMIPURE 100

CLOMIPURE 100 by AKUMENTIS HEALTHCARE LTD is a medication primarily used in the management of female infertility.

• Name:

  • Brand Name: CLOMIPURE 100
  • Common Name: Clomipure 100 Capsule

• Composition:

  • CLOMIPURE 100 contains a fixed-dose combination of:
    • Clomiphene: 100 mg
    • Melatonin: 3 mg

• Uses: CLOMIPURE 100 is indicated for the treatment of female infertility. It is prescribed for women who experience:

  • Anovulation (inability to produce eggs) or oligo-ovulation (production of too few eggs).
  • Infertility associated with Polycystic Ovarian Syndrome (PCOS). Clomiphene in the capsule works by stimulating hormones essential for ovulation. Melatonin acts as an antioxidant, safeguarding cells from free radicals that can impair fertility.

• Dosage and Administration:

  • CLOMIPURE 100 should be taken exactly as advised by a healthcare professional, with or without food.
  • Swallow the capsule whole with water; do not chew, crush, or break it.
  • The specific dosage and duration of treatment are determined by the doctor based on the patient's condition.
  • It is generally not recommended for prolonged periods and may be repeated for a maximum of four menstrual cycles.
  • Do not exceed the prescribed dose.

• Side Effects: Common side effects may include:

  • Nausea, vomiting, and headache
  • Hot flashes (red and warm face)
  • Abdominal pain or discomfort
  • Breast tenderness or discomfort
  • Blurred vision
  • Mood swings
  • Ovarian hyperstimulation syndrome (OHSS) Most side effects are usually temporary; however, consult a doctor if they persist or worsen.

• Precautions:

  • Pregnancy: CLOMIPURE 100 is highly unsafe and contraindicated during pregnancy. A negative pregnancy test must be confirmed before starting treatment, and the medication should be stopped immediately if pregnancy is suspected.
  • Breastfeeding: Use is probably unsafe as information on its passage into breast milk is limited, and it may reduce milk production. Consult a doctor.
  • Driving & Machinery: May cause blurred vision; caution is advised when driving or operating machinery.
  • Alcohol: It is advisable to avoid alcohol consumption due to limited information on interactions and potential unsafety.
  • Liver Disease: CLOMIPURE 100 is probably unsafe and should be avoided in patients with liver disease.
  • Kidney Disease: Use with caution in patients with kidney disease, as information is limited.
  • Inform your doctor about any allergies to its components, existing ovarian cysts, unusual vaginal bleeding of unknown cause, hormone-sensitive cancers, or any other medical conditions and medications being taken to prevent potential interactions.

• Storage:

  • Store CLOMIPURE 100 in a cool and dry place, away from direct sunlight.
  • Keep it out of the sight and reach of children and pets.
  • Optimal storage temperature is below 25°C or at room temperature (20-25°C), not exceeding 30°C.
  • Protect from light and moisture.

Here are frequently asked questions and answers about CLOMIPURE 100 by AKUMENTIS HEALTHCARE LTD:

What is CLOMIPURE 100 used for?

CLOMIPURE 100 is a combination medicine primarily used to treat female infertility. It is prescribed for women who have difficulty getting pregnant because they are not ovulating (anovulation or oligo-ovulation) or those with Polycystic Ovarian Syndrome (PCOS).

How does CLOMIPURE 100 work?

CLOMIPURE 100 contains two active ingredients: Clomiphene (Clomifene) and Melatonin. Clomiphene is a selective estrogen receptor modulator (SERM) that works by stimulating the release of hormones, specifically Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH), from the pituitary gland. These hormones are essential for the growth and release of eggs from the ovary (ovulation). Melatonin acts as an antioxidant, helping to protect cells from damage caused by free radicals that can contribute to infertility.

What is the usual dosage of CLOMIPURE 100?

CLOMIPURE 100 should be taken exactly as prescribed by your doctor. The dosage and duration depend on your specific medical condition and response to treatment. It can be taken with or without food, preferably at a fixed time each day. The capsule should be swallowed whole with a glass of water and not chewed, crushed, or broken.

What are the possible side effects of CLOMIPURE 100?

Common side effects may include hot flashes, headache, nausea, vomiting, abdominal pain or discomfort, bloating, breast tenderness, and mood swings. Most of these side effects are usually temporary and resolve over time. If any side effects persist or worsen, you should consult your doctor. Blurred vision is also a possible side effect, and caution should be exercised when driving or operating machinery.

Is CLOMIPURE 100 safe during pregnancy or breastfeeding?

Pregnancy: CLOMIPURE 100 is considered highly unsafe and contraindicated during pregnancy. You must not use this medicine if you are pregnant or suspect you might be pregnant. A negative pregnancy test should be confirmed before initiating treatment. If you become pregnant during treatment, stop taking the medicine immediately and inform your doctor. Breastfeeding: It is probably unsafe to use CLOMIPURE 100 while breastfeeding. Limited human data suggests the medicine may pass into breast milk and potentially harm the nursing baby. It can also reduce milk production. Always consult your doctor if you are breastfeeding or plan to breastfeed.

Can CLOMIPURE 100 be taken with other medications?

It is important to inform your doctor about all other medicines, including prescription drugs, over-the-counter medications, supplements, and herbal products, you are currently taking or plan to take. This helps to avoid potential drug interactions. Specific medications like Fluvoxamine, Psoralens, Cimetidine, Estrogens, certain antibiotics (e.g., Ciprofloxacin), Rifampicin, and Carbamazepine may interact with CLOMIPURE 100. It is also considered unsafe to consume alcohol while taking CLOMIPURE 100.

What precautions should be taken while using CLOMIPURE 100?

Before starting treatment, your doctor may evaluate hormone levels and conduct a uterine examination. You should not exceed the prescribed dose. Inform your doctor if you have liver disease, kidney impairment, ovarian cysts, unexplained vaginal bleeding, hormone-dependent cancers, early menopause, uterine fibroids, or a history of conditions like epilepsy or diabetes. CLOMIPURE 100 may cause blurred vision, so it's advisable to avoid driving or operating heavy machinery until your vision is clear and you are alert. There is an increased risk of multiple pregnancies with this medication.

What happens if a dose of CLOMIPURE 100 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you forget a dose, it is best to talk to your doctor, as you may need to adjust your treatment cycle.

How should CLOMIPURE 100 be stored?

CLOMIPURE 100 should be stored in a cool and dry place, away from direct sunlight. The recommended storage temperature is typically below 25°C or between 10°C to 25°C (or below 30°C). Keep the medicine out of sight and reach of children and pets.