Maxgalin Er 75 Tab

MAXGALIN ER 75 Tablet

MAXGALIN ER 75 Tablet, marketed by SUN - AKUNA, is an extended-release medication primarily used to manage various neurological pain conditions and seizure disorders.

Composition

• Active Ingredient: Pregabalin (75mg)

Uses

MAXGALIN ER 75 Tablet is prescribed for the prevention and treatment of several medical conditions:

• Neuropathic Pain: Pain caused by damaged nerves, often associated with conditions like diabetes, shingles (herpes zoster infection), spinal cord injury, or other nerve damage.
• Epilepsy: Used as an adjunctive therapy to control partial-onset seizures (fits) in adults.
• Fibromyalgia: Manages widespread musculoskeletal pain, stiffness, and tenderness.
• Neuralgia: Relief from nerve pain.
• Anxiety Disorder: May be prescribed for generalized anxiety disorders when other treatments are unsuitable (off-label use).

Dosage and Administration

• MAXGALIN ER 75 Tablet should be taken exactly as prescribed by your doctor.
• Swallow the tablet whole with a glass of water; do not crush, chew, break, or open it.
• It can be taken with or without food.
• For optimal results, it is generally recommended to take the medicine at the same time each day.
• Your doctor will determine the appropriate dosage and duration of treatment based on your medical condition, usually starting with a low dose and gradually increasing it.
• Do not exceed the prescribed dose or stop the medication suddenly without consulting your doctor, as this may lead to withdrawal symptoms.

Side Effects

Common side effects include:

• Dizziness
• Somnolence (sleepiness or drowsiness)
• Dry mouth
• Oedema (fluid build-up with swelling in hands, legs, or feet)
• Blurred vision
• Weight gain
• Abnormal thinking (difficulty with concentration or attention)
• Headache
• Fatigue
• Peripheral edema

Less common but serious side effects or concerns to report to your doctor include suicidal thoughts or behavior and signs of an allergic reaction such as bumps, itching, swelling around the face or other body parts, or difficulty breathing.

Precautions

• Allergies: Inform your doctor if you are allergic to Pregabalin or any other ingredients of the tablet.
• Pregnancy and Breastfeeding: MAXGALIN ER 75 Tablet is not recommended during pregnancy or breastfeeding unless specifically advised by your doctor. Women of childbearing age should use effective contraception during treatment.
• Children: Its safety and effectiveness have not been established in children under 18 years of age, so it is not recommended for this age group.
• Driving and Operating Machinery: This medicine may cause decreased concentration, drowsiness, dizziness, or blurred vision. Avoid driving or operating machinery until you are fully alert and aware of how the medicine affects you.
• Alcohol: Avoid consuming alcohol as it can worsen side effects such as dizziness and drowsiness.
• Medical History: Inform your doctor about any pre-existing medical conditions, including kidney disease (dose adjustment may be needed), liver disease, heart problems (may increase risk of heart failure), diabetes (monitor blood sugar and weight), history of alcohol or drug addiction, mood disorders, depression, suicidal thoughts, bleeding disorders, chronic obstructive pulmonary disease (COPD), respiratory disorders, or a history of fits.
• Elderly Patients: Use with caution in elderly patients (over 65 years) as they may be more susceptible to side effects like dizziness, which can increase the risk of accidental falls.
• Discontinuation: Do not stop taking MAXGALIN ER 75 Tablet suddenly, as this can lead to withdrawal symptoms. The dosage should be gradually reduced under medical supervision.

Storage

• Store in a cool and dry place, away from direct sunlight.
• Keep out of sight and reach of children.
• Maintain storage temperatures between 10ºC to 25ºC or below 30ºC.
• Protect the medicine from light and moisture.

MAXGALIN ER 75 TAB contains pregabalin, an extended-release medication used to manage various nerve-related conditions. Here are some frequently asked questions about this medicine:

What is MAXGALIN ER 75 TAB used for?

MAXGALIN ER 75 TAB is primarily used to treat neuropathic pain, which is pain caused by nerve damage. This includes pain associated with diabetic peripheral neuropathy (nerve damage from diabetes), postherpetic neuralgia (pain after shingles), and neuropathic pain associated with spinal cord injury. It is also used to manage fibromyalgia, a chronic condition characterized by widespread pain, fatigue, and stiffness. Additionally, it can be used as an add-on therapy for adults with partial-onset seizures.

How does MAXGALIN ER 75 TAB work?

The active ingredient, pregabalin, works by calming damaged or overactive nerves in the body. It does this by reducing the release of certain chemical messengers (neurotransmitters) in the brain that are responsible for transmitting pain signals. Pregabalin binds to a specific part of nerve cells (the alpha-2-delta subunit of voltage-dependent calcium channels) in the central nervous system to achieve its effects.

What is the usual dosage for MAXGALIN ER 75 TAB?

MAXGALIN ER 75 TAB is an extended-release tablet and is typically taken once daily, preferably after an evening meal. Your doctor will determine the exact dosage based on your condition and how you respond to the medication. For conditions like diabetic nerve pain or postherpetic neuralgia, initial doses for extended-release pregabalin often start around 165 mg once daily and may be increased within a week. While doses up to 660 mg per day have been studied, doses above 330 mg per day are usually reserved for patients who tolerate lower doses and continue to experience ongoing pain, due to an increased risk of side effects. It is crucial to swallow the tablet whole and not to crush, split, or chew it.

What are the possible side effects of MAXGALIN ER 75 TAB?

Common side effects include dizziness, drowsiness, blurred vision, weight gain, dry mouth, and swelling in the hands or feet (peripheral edema). If these effects are bothersome or persistent, inform your doctor. More serious, though less common, side effects can include severe allergic reactions (such as angioedema, which involves swelling of the face, lips, tongue, or throat), thoughts of self-harm or worsening mood, and breathing problems. Seek immediate medical attention if you experience severe allergic reactions or significant breathing difficulties.

Is MAXGALIN ER 75 TAB safe during pregnancy or breastfeeding?

Pregnancy: MAXGALIN ER 75 TAB (pregabalin) should generally only be used during pregnancy if the potential benefits outweigh the risks. Animal studies have shown some developmental toxicity, and while human studies are limited, some suggest a small, unclear risk of birth defects. It is important to discuss your pregnancy or plans to become pregnant with your doctor. They may recommend enrolling in a pregnancy registry to monitor the effects of the medication.

Breastfeeding: Pregabalin passes into breast milk. The manufacturer generally advises against breastfeeding during treatment due to a potential risk of tumorigenicity observed in animal studies. While limited human data show low levels in breast milk and one infant experienced no adverse effects over three months, it's essential to discuss the risks and benefits with your healthcare provider to determine the best feeding method for your baby.

Can MAXGALIN ER 75 TAB be taken with other medications?

Yes, MAXGALIN ER 75 TAB can interact with other medications. It is especially important to inform your doctor about any other central nervous system (CNS) depressants you are taking, such as opioids, benzodiazepines (for anxiety or sleep), muscle relaxants, antihistamines, and alcohol. Combining these with pregabalin can increase side effects like dizziness, drowsiness, and may lead to severe breathing problems. Additionally, concurrent use with ACE inhibitors (certain blood pressure medications) may increase the risk of angioedema. Always provide your healthcare provider with a complete list of all your medications, supplements, and herbal products to avoid potential interactions.

What precautions should be taken while taking MAXGALIN ER 75 TAB?

Do not stop taking MAXGALIN ER 75 TAB suddenly, as this can lead to withdrawal symptoms (e.g., insomnia, nausea, headache, anxiety, diarrhea) or increased seizure frequency in patients with seizure disorders. Your doctor will guide you on how to gradually reduce the dose over at least one week if discontinuation is necessary. Avoid consuming alcohol and other CNS depressants while on this medication. Due to potential dizziness, drowsiness, or blurred vision, do not drive or operate machinery until you understand how the medicine affects you. Monitor for any changes in mood, worsening depression, or thoughts of self-harm and report them to your doctor immediately. If you have diabetes or heart problems, report any unusual swelling or rapid weight gain to your doctor.

What happens if a dose of MAXGALIN ER 75 TAB is missed?

If you miss a dose of MAXGALIN ER 75 TAB after your evening meal, take it as soon as you remember before bedtime, preferably after a snack. If you remember the missed dose the following morning, take it after your morning meal. If you remember after the morning meal, skip the missed dose and take your next scheduled dose at the usual time that evening. Do not take a double dose to make up for a missed one.

How should MAXGALIN ER 75 TAB be stored?

Store MAXGALIN ER 75 TAB at room temperature, typically between 20°C to 25°C (68°F to 77°F), with excursions permitted between 15°C and 30°C (59°F and 86°F). Keep it in its original packaging to protect it from moisture, heat, and light. Ensure it is stored out of the sight and reach of children. Do not store it in the bathroom.