Resner Plus Tablet (10 Tab)

Resner Plus Tablet (10 Tab) by Lupin Ltd.

Resner Plus Tablet is a combination medicine manufactured by Lupin Ltd., primarily used in the management of neuropathic pain.

Composition Each tablet contains a combination of three active ingredients:

• Methylcobalamin: 1500 mcg
• Nortriptyline: 10 mg
• Pregabalin: 75 mg

Uses Resner Plus Tablet is prescribed for the management of neuropathic pain, which includes conditions such as diabetic neuropathy, postherpetic neuralgia, sciatica, spinal cord injury, and fibromyalgia. It also addresses associated nutritional deficiencies and aids in the regeneration of damaged nerve cells.

Dosage and Administration This medicine should be taken orally as prescribed by a healthcare professional, with or without food. The tablet should be swallowed whole and not crushed, broken, or chewed. The dosage and duration of treatment are determined by the doctor based on the patient's medical condition. It is important not to stop the medication suddenly, as this may lead to withdrawal symptoms.

Side Effects Common side effects may include dizziness, sleepiness, dry mouth, blurred vision, weight gain, constipation, nausea, vomiting, and peripheral edema (swelling of hands or feet). Serious, though less common, side effects can include hypersensitivity reactions (e.g., skin rash, hives, difficulty breathing), thoughts of self-harm, significant mood or behavioral changes, and hallucinations.

Precautions

• Avoid alcohol consumption while taking Resner Plus Tablet, as it can increase dizziness and drowsiness.
• This medicine may cause dizziness and blurred vision; therefore, caution is advised when driving or operating machinery.
• Resner Plus Tablet is generally not recommended for children due to a lack of established safety and effectiveness.
• Pregnant or breastfeeding women should consult their doctor before use.
• Inform your doctor if you have liver or kidney problems, diabetes, heart conditions, or a history of seizures.
• Due to the Pregabalin component, there is a potential for abuse and dependence; use strictly as prescribed.
• Inform your doctor about all other medications, including over-the-counter drugs, herbal supplements, and vitamins, to prevent potential drug interactions.

Storage Store Resner Plus Tablet in its original packaging at room temperature (between 15-25°C or 20-25°C) in a clean, dry place, away from moisture, heat, and direct sunlight. Keep out of the sight and reach of children.

Here are the frequently asked questions about Resner Plus Tablet:

What is Resner Plus Tablet used for?

Resner Plus Tablet is a combination medicine primarily used to manage neuropathic pain. This includes pain associated with diabetic peripheral neuropathy, postherpetic neuralgia (shingles), sciatica, spinal cord injury, and fibromyalgia. It can also be used for nutritional deficiencies.

How does Resner Plus Tablet work?

Resner Plus Tablet contains three active ingredients: Methylcobalamin, Nortriptyline, and Pregabalin. Methylcobalamin (a form of Vitamin B12) helps in the production of myelin, a substance that protects nerve fibers and aids in the regeneration of damaged nerve cells. Nortriptyline is a tricyclic antidepressant that works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the brain, which helps reduce pain signals. Pregabalin is an anti-convulsant that decreases pain by modulating calcium channel activity of the nerve cells, thereby interfering with pain messages traveling through the brain and spinal cord. Together, these ingredients synergistically relieve neuropathic pain and improve nerve health.

What is the usual dosage of Resner Plus Tablet?

The dosage and duration of treatment with Resner Plus Tablet are determined by your doctor based on your specific medical condition and response to treatment. It should be taken exactly as prescribed, with or without food, and swallowed whole with a glass of water. Do not crush, break, or chew the tablets.

What are the possible side effects of Resner Plus Tablet?

Common side effects include dizziness, sleepiness, blurred vision, dry mouth, weight gain, constipation, and swelling of the hands or feet (peripheral oedema). Most of these side effects are usually temporary and subside over time. If they persist or worsen, consult your doctor. Serious but rare side effects can include changes in mood or behavior, suicidal thoughts, difficulty breathing, or allergic reactions.

Is Resner Plus Tablet safe during pregnancy or breastfeeding?

Resner Plus Tablet should be used with caution during pregnancy, and only if prescribed by your doctor, as animal studies have shown potential harmful effects on the developing baby. For breastfeeding mothers, it is generally considered unsafe as the drug may pass into breast milk and could harm the infant. It is recommended to consult your doctor before taking this medication while breastfeeding.

Can Resner Plus Tablet be taken with other medications?

It is important to inform your doctor about all other medications, supplements, and herbal products you are currently taking to avoid potential drug interactions. Resner Plus Tablet may interact with certain antidepressant medications (e.g., duloxetine, sertraline, escitalopram), pain relievers, and medicines for diabetes, psychiatric illnesses, blood pressure, Parkinson's disease, or heart problems. Patients taking Monoamine Oxidase Inhibitors (MAOIs) or those with heart problems or glaucoma should use Resner Plus Tablet with caution.

What precautions should be taken while taking Resner Plus Tablet?

Avoid consuming alcohol while taking Resner Plus Tablet, as it can increase dizziness and sleepiness. This medicine may also cause drowsiness, dizziness, and blurred vision, so it's advised not to drive or operate machinery until you know how it affects you. Do not stop taking the medicine suddenly without consulting your doctor, as this can lead to withdrawal symptoms. Caution is advised for patients with kidney or liver impairment, diabetes, thyroid problems, or a history of fits.

What happens if a dose of Resner Plus Tablet is missed?

If you miss a dose of Resner Plus Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects.

How should Resner Plus Tablet be stored?

Resner Plus Tablet should be stored at room temperature, typically between 15-25°C or below 30°C, away from moisture and heat. Keep it in its original packaging and out of the sight and reach of children. Do not use the medicine after its expiry date.