Zita Pio Tablet (15 Tab)

ZITA PIO TABLET is a combination medication used to manage Type 2 Diabetes Mellitus in adults. It is manufactured by Glenmark Pharmaceuticals Ltd..

Composition

ZITA PIO TABLET contains two active ingredients:

• Pioglitazone (15mg): A thiazolidinedione that enhances the body's sensitivity to insulin.
• Teneligliptin (20mg): A dipeptidyl peptidase-4 (DPP-4) inhibitor that increases insulin release from the pancreas and decreases hormones that raise blood sugar levels.

Uses

ZITA PIO TABLET is prescribed for the treatment of Type 2 Diabetes Mellitus in adults. It helps control blood sugar levels, which can reduce the risk of serious complications such as kidney damage, eye damage, nerve problems, and loss of limbs.

Dosage and Administration

This medicine can be taken with or without food, typically once daily or as directed by a doctor. It should be swallowed whole with a glass of water and not chewed or crushed. Consistent daily intake at the same time is recommended for optimal benefits. The doctor will determine the appropriate dosage based on the patient's condition and response to treatment.

Side Effects

Common side effects may include:

• Headache
• Muscle pain, back pain, joint pain
• Nose irritation (nasopharyngitis), upper respiratory tract infection
• Vision problems (e.g., blurred vision)
• Hypoglycemia (low blood sugar), especially when taken with other antidiabetic medicines or if meals are skipped
• Weight gain, swelling (edema)
• Constipation, diarrhea

Serious side effects, though rare, can include symptoms of heart failure (e.g., unusual shortness of breath, rapid weight gain, swelling in legs) or signs of bladder cancer (e.g., blood in urine, pain while urinating).

Precautions

ZITA PIO TABLET is not recommended for individuals with Type 1 Diabetes Mellitus, diabetic ketoacidosis, or severe kidney or liver disease. Caution is advised for patients with a history of heart disease, particularly heart failure, as pioglitazone may worsen heart-related conditions. It is contraindicated during pregnancy and breastfeeding. Patients should inform their doctor about all existing health conditions and other medications being taken.

Storage

Store ZITA PIO TABLET in a cool and dry place, away from direct sunlight, at temperatures between 10ºC to 25ºC or below 30ºC. Keep it out of reach and sight of children.

Here are some frequently asked questions about ZITA PIO TABLET (15 TAB) by GLENMARK PHARMACEUTICALS LTD., along with their concise answers:

What is ZITA PIO Tablet used for?

ZITA PIO Tablet is primarily used to manage type 2 diabetes mellitus in adults. It helps control high blood sugar levels when diet and exercise alone are not sufficient, or when a single medication isn't enough. By controlling blood sugar, it helps prevent serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs.

How does ZITA PIO Tablet work?

ZITA PIO Tablet is a combination of two active ingredients: Pioglitazone and Teneligliptin. Pioglitazone works by increasing the body's sensitivity to insulin in muscle, fat tissue, and the liver, which improves how cells take up and use glucose. Teneligliptin inhibits an enzyme called DPP-4, which helps to increase the release of insulin from the pancreas and decrease hormones that raise blood sugar levels, thereby regulating blood glucose. Together, these actions help to effectively lower blood sugar.

What is the usual dosage for ZITA PIO Tablet?

The usual dosage of ZITA PIO Tablet is once daily, or as prescribed by your doctor. It can be taken with or without food. It's important to swallow the tablet whole with a glass of water, without chewing or crushing it, and to take it at the same time each day for consistent results. Never exceed the recommended dose or adjust it without consulting your doctor.

What are the possible side effects of ZITA PIO Tablet?

Common side effects include nasopharyngitis (inflammation of the nose and throat), upper respiratory tract infections, back pain, headache, muscle pain, joint pain, peripheral edema (swelling in the ankles and feet), and weight gain. Some people may also experience low blood sugar (hypoglycemia), abnormal vision, constipation, or diarrhea. If you experience severe symptoms like unusual shortness of breath, rapid weight gain, severe swelling, signs of bladder cancer (e.g., blood in urine), or an increased risk of fractures, contact your doctor immediately.

Is ZITA PIO Tablet safe during pregnancy or breastfeeding?

ZITA PIO Tablet is generally not recommended for use during pregnancy and is contraindicated for breastfeeding women, as it may pass into breast milk. It is crucial to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, to discuss alternative treatment options.

Can ZITA PIO Tablet be taken with other medications?

ZITA PIO Tablet can interact with several other medications. For example, taking it with insulin or other insulin-stimulating drugs (like sulfonylureas) can increase the risk of low blood sugar. Medications like gemfibrozil (for cholesterol) or NSAIDs (for pain relief) may also interact. Always inform your doctor about all prescription drugs, over-the-counter medicines, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using ZITA PIO Tablet?

Do not take ZITA PIO Tablet if you have type 1 diabetes, diabetic ketoacidosis, or if you are allergic to any of its ingredients. Caution is advised for individuals with heart disease (especially heart failure), severe kidney or liver disease, or a history of bladder cancer. This medicine may cause dizziness or fatigue, so exercise caution when driving or operating machinery. It is also advisable to avoid alcohol consumption, as it can intensify side effects and affect blood sugar control. Your doctor may recommend regular monitoring of your blood sugar levels and liver function.

What happens if a dose of ZITA PIO Tablet is missed?

If you forget to take your usual dose of ZITA PIO Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should ZITA PIO Tablet be stored?

ZITA PIO Tablet should be stored in a cool and dry place, away from direct sunlight and moisture. Keep the medicine out of reach and sight of children. It is typically stored at room temperature, ideally between 20-25°C.