Oxramet G 5/1/500

OXRAMET G 5/1/500

Name:

• Brand Name: OXRAMET G 5/1/500. This medicine is manufactured by Sun Pharmaceutical Industries Ltd.

Composition: OXRAMET G 5/1/500 is a combination medication containing three active ingredients:

• Dapagliflozin (5 mg)
• Glimepiride (1 mg)
• Metformin (500 mg)

Uses: This antidiabetic medicine is prescribed for the treatment of Type 2 Diabetes Mellitus in adults. It helps manage high blood sugar levels by:

• Removing excess glucose from the body via urine (Dapagliflozin).
• Stimulating insulin production by the pancreas and improving the body's response to insulin (Glimepiride).
• Reducing glucose production in the liver and delaying sugar absorption from the intestines (Metformin). It also aids in improving glycemic control, reducing HbA1c levels, and preventing diabetes-related complications such as kidney damage, nerve issues, and heart disease.

Dosage and Administration: OXRAMET G 5/1/500 should be taken exactly as prescribed by a doctor. It is typically taken with the first meal of the day. Patients should not exceed the recommended dose or discontinue the medicine without consulting their doctor.

Side Effects: Common side effects may include:

• Hypoglycemia (low blood sugar)
• Nausea, vomiting, abdominal pain
• Headache, dizziness, asthenia (weakness)
• Allergic reactions
• Urinary tract infections and genital fungal infections

Serious side effects, though rare, can include lactic acidosis (due to Metformin accumulation) and severe urinary tract infections.

Precautions:

• Avoid if allergic to any components of the medicine.
• Inform your doctor about any pre-existing kidney or liver disease, heart problems, or a history of diabetic ketoacidosis.
• Not recommended for pregnant or breastfeeding women, or children under 18 years of age.
• Avoid alcohol consumption as it increases the risk of hypoglycemia and lactic acidosis.
• Stay hydrated, as the medicine may increase urination and lead to dehydration.
• Inform your doctor about other medications, including supplements, as interactions can occur with diuretics, insulin, and certain diagnostic agents.

Storage: Store OXRAMET G 5/1/500 in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. It should be stored at temperatures between 10ºC and 25ºC or below 30ºC.

Here are the most frequently asked questions about OXRAMET G 5/1/500, along with concise answers:

What is OXRAMET G 5/1/500 used for?

OXRAMET G 5/1/500 is an anti-diabetic medication primarily used to treat Type 2 Diabetes Mellitus in adults. It helps control high blood sugar levels, especially when lifestyle changes, such as diet and exercise, and other treatments are not sufficient to manage the condition. By managing blood sugar, it helps reduce the chances of serious diabetes complications like kidney damage and heart disease.

How does OXRAMET G 5/1/500 work?

OXRAMET G 5/1/500 is a combination of three active ingredients: Dapagliflozin (5mg), Glimepiride (1mg), and Metformin (500mg).

• Dapagliflozin works by causing the kidneys to remove excess sugar from the body through urine.
• Metformin decreases the production of glucose by the liver, reduces the absorption of sugar from the intestines, and improves the body's sensitivity to insulin.
• Glimepiride stimulates the beta cells in the pancreas to produce and release more insulin. Together, these mechanisms help to lower blood sugar levels effectively.

What is the usual dosage for OXRAMET G 5/1/500?

The specific dosage of OXRAMET G 5/1/500 will be determined by your doctor based on your individual condition. It should be taken as prescribed, typically with the first meal of the day. It's crucial not to exceed the recommended dose.

What are the possible side effects of OXRAMET G 5/1/500?

Common side effects may include low blood sugar (hypoglycemia), vomiting, nausea, abdominal pain, headache, dizziness, and allergic reactions. Serious side effects can include lactic acidosis (a rare but severe buildup of lactic acid in the blood) and severe urinary tract infections. If any side effects persist, worsen, or if you experience signs of lactic acidosis (e.g., severe tiredness, muscle cramps, difficulty breathing), seek immediate medical attention.

Is OXRAMET G 5/1/500 safe during pregnancy or breastfeeding?

OXRAMET G 5/1/500 is generally not recommended during pregnancy or breastfeeding due to limited information on its effects. If you are pregnant, planning a pregnancy, or breastfeeding, you should inform your doctor, who may suggest alternative treatments.

Can OXRAMET G 5/1/500 be taken with other medications?

OXRAMET G 5/1/500 can interact with other medications. For example, taking it with diuretics (water pills) may increase the risk of dehydration and low blood pressure. Combining it with insulin or other insulin secretagogues can lead to extremely low blood sugar levels. It's important to inform your doctor about all medicines, including over-the-counter drugs, herbal supplements, and vitamins, you are currently taking to avoid potential interactions.

What precautions should be taken while using OXRAMET G 5/1/500?

Several precautions should be observed:

• Alcohol Consumption: Avoid excessive alcohol intake, as it can increase the risk of lactic acidosis and hypoglycemia.
• Medical Conditions: Inform your doctor if you have kidney or liver problems, heart conditions, allergies to any ingredients (especially sulfa drugs), or a history of diabetic ketoacidosis.
• Hydration: Stay well-hydrated, as the dapagliflozin component can increase urination and lead to dehydration.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is typically recommended.
• Age: This medicine is not recommended for use in children below 18 years of age.

What happens if a dose of OXRAMET G 5/1/500 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can cause your blood sugar to fall rapidly.

How should OXRAMET G 5/1/500 be stored?

Store OXRAMET G 5/1/500 in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. The typical storage temperature is between 10ºC to 25ºC or below 30ºC.