Voage M 10 Mg/500 Mg Tablet (10 Tab)

VOAGE M 10 MG/500 MG TABLET

VOAGE M 10 MG/500 MG TABLET is an antidiabetic medication manufactured by Alembic Pharmaceuticals Ltd. It is prescribed for adults to manage Type 2 Diabetes Mellitus.

• Composition

  • Active Ingredients: Dapagliflozin (10 mg) and Metformin (500 mg).
  • Dapagliflozin is a sodium-glucose co-transporter-2 (SGLT2) inhibitor, while Metformin belongs to the biguanide class of drugs.

• Uses

  • Treatment of Type 2 Diabetes Mellitus in adults, especially when diet and exercise alone do not provide adequate blood sugar control.
  • Helps reduce the risk of hospitalization due to heart failure in adults with Type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors.

• Dosage and Administration

  • Typically taken orally once daily, usually in the morning, with or without food, as directed by a physician.
  • The exact dosage and duration will be determined by the doctor based on the patient's medical condition and response to treatment.
  • Tablets should be swallowed whole; do not crush or chew.

• Side Effects

  • Common: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, headache, dizziness, frequent urination, mild skin rash or itchy skin, genital mycotic infections, urinary tract infections, dehydration, low blood pressure, sore throat, stuffy or runny nose, and a metallic taste in the mouth.
  • Serious (rare): Lactic acidosis (symptoms may include severe tiredness, muscle cramps, difficulty breathing, dizziness, light-headedness), severe allergic reactions, and liver problems. Seek immediate medical attention if these occur.

• Precautions

  • Contraindicated in patients with Type 1 Diabetes Mellitus, severe kidney or liver disease, diabetic ketoacidosis, severe infection, or dehydration.
  • Avoid alcohol consumption as it can increase the risk of lactic acidosis.
  • Not generally recommended during pregnancy (especially the second and third trimesters) or while breastfeeding.
  • Caution is advised for elderly patients (above 65 or 70 years) and individuals with heart failure, low blood pressure, or a history of pancreatitis.
  • Inform the doctor about all other medications, including diuretics, insulin, and carbonic anhydrase inhibitors, to avoid potential drug interactions.
  • Regular monitoring of blood sugar levels and kidney function is essential during treatment.

• Storage

  • Store in a cool and dry place, away from direct sunlight, typically below 30°C.
  • Keep out of sight and reach of children.

What is VOAGE M 10 MG/500 MG TABLET used for?

VOAGE M 10 MG/500 MG TABLET is primarily used to treat high blood sugar levels in adults with type 2 diabetes mellitus. It is typically prescribed alongside diet and exercise when these alone are insufficient to control blood sugar. This medicine also helps reduce the risk of hospitalization due to heart failure in adults with type 2 diabetes and existing cardiovascular disease or multiple cardiovascular risk factors.

How does VOAGE M 10 MG/500 MG TABLET work?

This medication contains two active ingredients: Dapagliflozin (10 mg) and Metformin (500 mg). Dapagliflozin is an SGLT2 inhibitor that works by blocking a protein in the kidneys, causing the body to remove excess sugar from the bloodstream through urine. Metformin is a biguanide that reduces the production of glucose in the liver, delays glucose absorption from the intestines, and improves the body's sensitivity to insulin. Together, they provide better control of blood sugar levels.

What is the usual dosage of VOAGE M 10 MG/500 MG TABLET?

The usual dosage is typically one tablet taken once daily, often in the morning, with or without food, as directed by your doctor. The dosage is individualized based on your medical condition and response to treatment. It is crucial to adhere to the prescribed dosage and not to exceed it without consulting your doctor.

What are the possible side effects of VOAGE M 10 MG/500 MG TABLET?

Common side effects can include nausea, vomiting, diarrhea, headache, dizziness, frequent urination, mild skin rash or itchy skin, stomach ache, loss of appetite, genital mycotic infections, urinary tract infections, dehydration, and low blood pressure. A less common but serious side effect is lactic acidosis, which requires immediate medical attention and may present with symptoms like vomiting, stomach pain, muscle cramps, severe tiredness, difficulty breathing, and low body temperature.

Is VOAGE M 10 MG/500 MG TABLET safe during pregnancy or breastfeeding?

VOAGE M 10 MG/500 MG TABLET is generally not recommended during the second and third trimesters of pregnancy unless considered clearly necessary, and consultation with a doctor is essential. It is also not recommended for use during breastfeeding, as it may pass into breast milk, and medical advice should be sought.

Can VOAGE M 10 MG/500 MG TABLET be taken with other medications?

This medicine can interact with other medications. For instance, concomitant use with diuretics (like furosemide or hydrochlorothiazide) may increase the risk of dehydration and low blood pressure. Using it with insulin or insulin secretagogues (like sulphonylurea) may increase the risk of extremely low blood sugar levels. It may also interact with carbonic anhydrase inhibitors and certain cationic medicines such as amiloride and digoxin. It should not be used if undergoing X-rays with iodinated contrast agents. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking.

What precautions should be taken while taking VOAGE M 10 MG/500 MG TABLET?

It is important to avoid alcohol consumption while taking this medicine, as it may increase the risk of lactic acidosis and low blood sugar levels. Inform your doctor if you have kidney or liver problems, heart disease, severe infections, dehydration, low blood pressure, or a history of yeast infections. This medicine is not for individuals with type 1 diabetes mellitus or severe kidney/liver disease. Regular monitoring of blood sugar levels is essential. It is generally not recommended for children under 18 years of age or for individuals aged 85 years or older. Staying hydrated by drinking plenty of fluids is also important.

What happens if a dose of VOAGE M 10 MG/500 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should VOAGE M 10 MG/500 MG TABLET be stored?

VOAGE M 10 MG/500 MG TABLET should be stored in a cool and dry place, away from direct sunlight, typically below 30°C. It is important to keep this medicine out of the sight and reach of children.