Itaspor Sb 50 Mg Capsule

ITASPOR SB 50 MG CAPSULE

Name

• Common Name: Itaspor SB Capsule
• Brand Name: ITASPOR SB 50 MG CAPSULE by INTAS PHARMACEUTICALS LTD

Composition

• Active Ingredient: Itraconazole 50 mg

Uses

ITASPOR SB 50 MG CAPSULE is an antifungal medication primarily used to treat various fungal and yeast infections in adults. It works by inhibiting the growth of fungi by destroying their cell membranes.

It is prescribed for a wide range of conditions, including:

• Fungal infections of the mouth, throat (oral and esophageal candidiasis), vagina (thrush), skin (such as ringworm, candidiasis, dermatophytosis), fingernails, toenails (onychomycosis), and lungs.
• Systemic fungal infections like aspergillosis, blastomycosis, cryptococcosis, and histoplasmosis.

Dosage and Administration

ITASPOR SB 50 MG CAPSULE should be taken orally, swallowed whole with a glass of water, and preferably with food to minimize stomach upset and ensure optimal absorption. For best results, it should be taken at evenly spaced times.

The exact dosage and duration of treatment will vary depending on the type and severity of the infection, as well as individual patient factors such as age, weight, and medical history, and should always be as prescribed by a physician. It is crucial to complete the entire course of medication, even if symptoms improve, to prevent the infection from returning or developing resistance.

Side Effects

Common side effects may include:

• Nausea, vomiting, diarrhea, stomach pain (abdominal pain)
• Headache, dizziness
• Dyspepsia, constipation, tiredness
• Cough, cold, throat pain, back pain, menstrual disorders

Serious side effects, though less common, require immediate medical attention:

• Tingling, numbness, or weakness in the limbs (signs of neuropathy)
• Liver problems, indicated by severe lack of appetite, nausea, vomiting, severe tiredness, stomach pain, yellowing of skin and eyes (jaundice), dark urine, or pale stools.
• Allergic reactions such as severe skin rash, hives, severe irritation, or swelling of the face, lips, tongue, or other body parts.
• Irregular heartbeat, fits, blurred vision, double vision, or hearing loss.

Precautions

• Pregnancy and Breastfeeding: ITASPOR SB is not recommended during pregnancy (Pregnancy Category C) as it may cause fetal harm. It is also not recommended for breastfeeding mothers as it passes into breast milk. Women of childbearing age should use effective contraception during and after treatment as advised by their doctor.
• Organ Impairment: Use with caution in patients with liver disease (liver function tests may be monitored), kidney disease, heart problems (including heart failure), and lung disease. Inform your doctor if you experience symptoms of liver problems or heart failure.
• Alcohol: Avoid alcohol consumption as it may increase the risk of liver problems.
• Drug Interactions: Avoid taking antacids within 2 hours of ITASPOR SB as they can interfere with absorption. If antacids are necessary, take ITASPOR SB with a cola drink. Inform your doctor about all other medications, including herbal supplements, to avoid potential interactions, especially with strong opioid painkillers like fentanyl.
• Driving and Machinery: ITASPOR SB may cause dizziness, blurred vision, double vision, or hearing loss. Patients should exercise caution and avoid driving or operating machinery if they experience these side effects.
• Pediatric and Geriatric Use: Generally not recommended for children under 12 or elderly patients, unless specifically advised by a doctor in special cases.

Storage

Store ITASPOR SB 50 MG CAPSULE at room temperature, ideally between 10ºC to 25ºC or below 30ºC. Keep it in a dry place, away from direct sunlight and excessive moisture. Ensure it is kept out of the sight and reach of children.

What is ITASPOR SB 50 MG CAPSULE used for?

ITASPOR SB 50 MG CAPSULE is an antifungal medication used to treat a variety of fungal and yeast infections in different parts of the body. These include infections of the mouth, throat, vagina (thrush), skin (like ringworm, athlete's foot, jock itch), fingernails, toenails, and systemic fungal infections such as aspergillosis, candidiasis, cryptococcosis, histoplasmosis, and blastomycosis. It works by stopping the growth of the fungi causing these infections.

How does ITASPOR SB 50 MG CAPSULE work?

ITASPOR SB 50 MG CAPSULE contains itraconazole, which is an azole antifungal. It works by targeting and disrupting the fungal cell membrane, a crucial structure for the fungus's integrity and survival. It does this by inhibiting a fungal enzyme called lanosterol 14-alpha-demethylase, which is essential for the synthesis of ergosterol, a key component of the fungal cell membrane. By interfering with ergosterol production, the medication weakens and ultimately destroys the fungal cell, preventing the infection from spreading and promoting healing.

What is the usual dosage for ITASPOR SB 50 MG CAPSULE?

The dosage of ITASPOR SB 50 MG CAPSULE can vary depending on the specific medical condition, severity of the infection, age, and weight. For adults, a standard dose for fungal infections might be one 100mg capsule taken twice a day for two weeks, though this can be adjusted. For children weighing 15-30kg, one 50mg capsule twice a day for two weeks is typical, while children over 30kg might take one 100mg capsule twice daily for two weeks. It should be taken exactly as prescribed by your doctor, swallowed whole with food to ensure optimal absorption and minimize stomach upset. It is crucial to complete the entire course of treatment, even if symptoms improve, to prevent the infection from returning and to reduce the risk of developing drug-resistant infections.

What are the possible side effects of ITASPOR SB 50 MG CAPSULE?

Common side effects can include nausea, vomiting, diarrhea, stomach pain, headache, dizziness, abdominal pain, constipation, and indigestion. More serious side effects, though less common, can include signs of liver problems (such as yellowing of the skin or eyes (jaundice), dark urine, pale stools, severe lack of appetite, unexplained stomach pain), severe skin rash, tingling, numbness or weakness in limbs, difficulty breathing, swelling of the face, lips, tongue or throat, or hearing loss. If any severe side effects occur, seek immediate medical attention.

Is ITASPOR SB 50 MG CAPSULE safe during pregnancy or breastfeeding?

No, ITASPOR SB 50 MG CAPSULE is generally not recommended during pregnancy or breastfeeding. It is considered a pregnancy category C drug and may cause harm to the unborn baby, including severe birth defects, especially if taken in high doses during pregnancy. It is also known to pass into breast milk and may affect the baby. Women of childbearing age should use reliable contraception while taking this medicine. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can ITASPOR SB 50 MG CAPSULE be taken with other medications?

ITASPOR SB 50 MG CAPSULE can interact with various other medications. It's important to inform your doctor about all medicines, including over-the-counter drugs and herbal supplements, you are taking. Specifically, avoid taking indigestion remedies (antacids) within 2 hours of taking ITASPOR SB, as they can interfere with its absorption. Certain antibiotics (e.g., rifampicin, isoniazid, rifabutin), medicines for fits (e.g., carbamazepine), some antiviral medicines (e.g., efavirenz), cholesterol-lowering medicines (e.g., atorvastatin, simvastatin), and medicines for irregular heartbeat (e.g., quinidine) can interact significantly.

What precautions should be taken with ITASPOR SB 50 MG CAPSULE?

Several precautions should be observed when taking ITASPOR SB 50 MG CAPSULE:

• Liver Function: Inform your doctor if you have a history of liver problems. Your doctor may monitor your liver function with blood tests, especially if treatment lasts longer than a month. Report any signs of liver issues immediately.
• Heart Conditions: Use with caution if you have a history of heart failure or irregular heartbeats, as it may worsen these conditions.
• Kidney Problems: Caution is advised for patients with kidney disease.
• Immune System: Not recommended for patients with a weak immune system (including HIV/AIDS).
• Driving: It may cause dizziness, blurred vision, or hearing loss; avoid driving or operating machinery if you experience these symptoms.
• Alcohol: Avoid alcohol consumption as it may increase the risk of liver problems.
• Children and Elderly: Generally not recommended for children under 12 or elderly patients unless specifically advised by a doctor.

What happens if a dose is missed?

If you miss a dose of ITASPOR SB 50 MG CAPSULE, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should ITASPOR SB 50 MG CAPSULE be stored?

ITASPOR SB 50 MG CAPSULE should be stored at room temperature, ideally between 10ºC to 25ºC or below 30ºC. Keep it in a dry place, away from excess heat, moisture, and direct sunlight. Always ensure it is kept out of the reach and sight of children and pets.