Oxramet G 5/2/500

OXRAMET G 5/2/500 Tablet

OXRAMET G 5/2/500 Tablet is a combination medication used to manage Type 2 Diabetes Mellitus in adults.

• Composition:

  • Dapagliflozin (5 mg)
  • Glimepiride (2 mg)
  • Metformin Hydrochloride (500 mg)

• Uses: OXRAMET G 5/2/500 Tablet is prescribed for the treatment of Type 2 Diabetes Mellitus. It helps control high blood sugar levels when lifestyle changes and dual therapy are insufficient. This medicine works by multiple mechanisms: Dapagliflozin aids in removing excess sugar from the body via urine, Metformin reduces sugar production in the liver and improves insulin sensitivity, and Glimepiride stimulates the pancreas to produce more insulin.

• Dosage and Administration: This medicine should be taken exactly as prescribed by a doctor, usually with the first meal of the day. It is crucial not to exceed the recommended dose or discontinue the medicine without consulting a healthcare professional.

• Side Effects: Common side effects include hypoglycemia (low blood sugar), nausea, vomiting, abdominal pain, headache, dizziness, increased urination, and allergic reactions. Serious side effects can include lactic acidosis (a rare but life-threatening buildup of lactic acid), severe urinary tract infections, and severe low blood sugar.

• Precautions: OXRAMET G 5/2/500 Tablet should be avoided if you are allergic to any of its components or have severe kidney or liver disease, Type 1 diabetes, or diabetic ketoacidosis. Caution is advised for pregnant or breastfeeding women, and individuals with heart problems or a history of low blood pressure. Alcohol consumption should be avoided as it increases the risk of hypoglycemia and lactic acidosis. Inform your doctor about all medications, supplements, or herbal products you are taking to prevent potential interactions.

• Storage: Store OXRAMET G 5/2/500 Tablet in a cool and dry place, away from direct sunlight and the sight and reach of children. The medicine should be stored at temperatures between 10ºC to 25ºC or below 30ºC.

OXRAMET G 5/2/500 is a medication prescribed for the management of Type 2 Diabetes Mellitus in adults. It contains a combination of three active ingredients: Dapagliflozin, Glimepiride, and Metformin.

Here are some frequently asked questions about OXRAMET G 5/2/500:

What is OXRAMET G 5/2/500 used for?

OXRAMET G 5/2/500 is an anti-diabetic medicine used to treat Type 2 Diabetes Mellitus in adults. It helps control high blood sugar levels, especially when lifestyle changes and dual therapy are not sufficient. By improving glycemic control, it aims to lower HbA1c levels and reduce the chances of serious diabetes complications like kidney damage, eye damage, nerve problems, and heart disease.

How does OXRAMET G 5/2/500 work?

This medicine combines three drugs, each with a distinct mechanism of action:

• Dapagliflozin (sodium-glucose cotransporter-2 inhibitor) helps remove excess sugar from the body through urine.
• Metformin (biguanide) reduces sugar production by cells in the liver, delays sugar absorption from the intestines, and enhances the body's response to insulin.
• Glimepiride (sulfonylurea) works by stimulating beta cells in the pancreas to produce more insulin, which helps move sugar from the blood into cells.

What is the usual dosage for OXRAMET G 5/2/500?

OXRAMET G 5/2/500 should be taken exactly as prescribed by your doctor. It can be taken with or without food, typically at the same time each day, often with the first meal. Do not exceed the recommended dose or discontinue the medicine without consulting your doctor. Your doctor may adjust the dose based on your blood glucose levels and response to treatment.

What are the possible side effects of OXRAMET G 5/2/500?

Common side effects may include low blood sugar levels (hypoglycemia), nausea, vomiting, abdominal pain, headache, dizziness, and allergic reactions. Other common side effects can be increased urination, genital infections, constipation, sore throat, and muscle pain. Serious but less common side effects include lactic acidosis (symptoms like muscle cramps, stomach pain, difficulty breathing), severe urinary tract infections, and severe low blood sugar. If side effects persist or worsen, consult your doctor.

Is OXRAMET G 5/2/500 safe during pregnancy or breastfeeding?

There is limited information on the use of OXRAMET G 5/2/500 during pregnancy, and it may be unsafe. Animal studies have shown adverse effects on the fetus. It is generally not recommended for use in breastfeeding mothers as it's unknown if it passes into human breast milk. It is crucial to inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before taking this medication.

Can OXRAMET G 5/2/500 be taken with other medications?

It is important to inform your doctor about all medicines, supplements, or herbal products you are currently taking, as OXRAMET G 5/2/500 can interact with them. Interactions can occur with diuretics (which may increase dehydration risk), insulin and insulin secretagogues (which may cause extremely low blood sugar), beta-blockers (which can mask hypoglycemia symptoms), and corticosteroids (which may reduce its effect). It should not be used with certain iodinated contrast agents or cimetidine.

What precautions should be taken while taking OXRAMET G 5/2/500?

Avoid consuming alcohol while taking this medicine, as it can increase the risk of lactic acidosis and low blood sugar. Inform your doctor if you have liver or kidney disease, heart problems, dehydration, or a history of bladder cancer. This medicine is not for Type 1 diabetes or diabetic ketoacidosis and is not recommended for children under 18 years of age. Regular monitoring of blood sugar levels and kidney function is recommended.

What happens if a dose of OXRAMET G 5/2/500 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this might cause your sugar level to fall rapidly.

How should OXRAMET G 5/2/500 be stored?

Store OXRAMET G 5/2/500 in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. It should be stored at temperatures between 10ºC to 25ºC or below 30ºC.