Mefomin Gz 80 Mg Tablet (15 Tab)

MEFOMIN GZ 80 MG TABLET (15 TAB)

MEFOMIN GZ 80 MG TABLET, manufactured by MACLEODS PHARMACEUTICALS LTD., is a combination medication for managing type 2 diabetes mellitus.

• Name:

  • Brand Name: MEFOMIN GZ 80 MG TABLET
  • Common Name: Gliclazide and Metformin

• Composition:

  • Active Ingredients: Each tablet contains Gliclazide (80 mg) and Metformin (500 mg).
  • Mechanism of Action: Gliclazide is a sulfonylurea that stimulates the pancreas to release more insulin. Metformin, a biguanide, reduces glucose production in the liver, delays glucose absorption from the intestines, and improves the body's response to insulin.

• Uses:

  • Primarily used to manage high blood sugar levels in adults with Type 2 Diabetes Mellitus when diet, exercise, and weight loss alone are insufficient.
  • Aids in improving glycemic control and insulin sensitivity.
  • May help prevent diabetes-related complications such as kidney damage, blindness, nerve problems, and reduce the risk of cardiovascular events.
  • Also indicated for the management of Polycystic Ovary Syndrome (PCOS) in some cases.

• Dosage and Administration:

  • Take MEFOMIN GZ 80 MG TABLET with food, preferably at the same time each day, or as advised by your physician.
  • Swallow the tablet whole with water; do not crush, chew, or break it.
  • The exact dose and duration will be determined by a healthcare professional based on individual patient response and condition.

• Side Effects:

  • Common: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, dizziness, headache, constipation, altered taste, and upper respiratory tract infection.
  • Hypoglycemia (low blood sugar): Symptoms include shakiness, dizziness, sweating, confusion, headache, and a fast heartbeat.
  • Serious (Rare): Lactic Acidosis (characterized by deep and rapid breathing, sleepiness, stomach pain, cold feeling in arms and legs), and Vitamin B12 deficiency with long-term use.

• Precautions:

  • Avoid if allergic to Gliclazide, Metformin, or any other ingredients.
  • Contraindicated in severe kidney or liver disease, Type 1 diabetes, and diabetic ketoacidosis.
  • Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.
  • Limit or avoid alcohol consumption due to increased risk of hypoglycemia and lactic acidosis.
  • Do not discontinue the medication without consulting your doctor, as this can lead to elevated blood sugar levels and serious complications.
  • Monitor blood sugar levels regularly.
  • Exercise caution while driving or operating machinery if you experience symptoms of low blood sugar.
  • Inform your doctor about all other medications, including herbal supplements, to avoid potential drug interactions.

• Storage:

  • Store in a cool, dry place, away from direct sunlight and moisture, ideally between 15°C and 30°C.
  • Keep out of the reach and sight of children.
  • Retain the medicine in its original packaging.

MEFOMIN GZ 80 MG TABLET is a medication primarily used to manage Type 2 Diabetes Mellitus. It contains two active ingredients: Gliclazide (80 mg) and Metformin (500 mg).

What is MEFOMIN GZ 80 MG TABLET used for?

MEFOMIN GZ 80 MG TABLET is prescribed for adults with Type 2 Diabetes Mellitus to help control high blood sugar levels. It is typically used when diet, exercise, and weight reduction alone have not been sufficient to manage blood glucose. By keeping blood sugar levels balanced, it helps prevent serious long-term complications of diabetes such as kidney damage, blindness, nerve problems, and heart disease.

How does MEFOMIN GZ 80 MG TABLET work?

This medicine works through the combined action of its two active ingredients. Gliclazide, a sulfonylurea, stimulates the pancreas to produce and release more insulin. Metformin, a biguanide, works by decreasing glucose production in the liver, delaying the absorption of glucose from the intestines, and improving the body's sensitivity to insulin. Together, these actions help to lower blood sugar levels.

What is the usual dosage for MEFOMIN GZ 80 MG TABLET?

The dosage of MEFOMIN GZ 80 MG TABLET (containing Gliclazide 80mg and Metformin 500mg) should be taken exactly as prescribed by your doctor. It is typically taken with meals, preferably at the same time each day. Your doctor will determine the appropriate dose for you, which may be adjusted based on your blood sugar levels and how you respond to the medication.

What are the possible side effects of MEFOMIN GZ 80 MG TABLET?

The most common side effect is hypoglycemia, or low blood sugar, which can cause symptoms like dizziness, weakness, drowsiness, headache, sweating, nervousness, shakiness, and intense hunger. Other common side effects may include abdominal pain, nausea, vomiting, indigestion, diarrhea, and constipation. These digestive effects can often be reduced by taking the medication with a meal. Serious but rare side effects can include severe skin reactions and blood disorders.

Is MEFOMIN GZ 80 MG TABLET safe during pregnancy or breastfeeding?

MEFOMIN GZ 80 MG TABLET is generally not recommended during pregnancy or breastfeeding. For pregnant individuals, caution is advised, and your doctor may recommend alternative treatments like insulin or metformin alone, which are considered safer during pregnancy. If you are breastfeeding, it is important to discuss the potential risks and benefits with your doctor, as gliclazide may pass into breast milk and could lower your baby's blood sugar level.

Can MEFOMIN GZ 80 MG TABLET be taken with other medications?

MEFOMIN GZ 80 MG TABLET can interact with several other medications, which may affect its blood sugar-lowering effect. Some medicines, such as certain antibiotics (e.g., sulfonamides, clarithromycin, quinolones), ACE inhibitors, some fungal infection treatments (e.g., miconazole, fluconazole), and certain painkillers (e.g., ibuprofen, aspirin), can strengthen its effects, increasing the risk of low blood sugar. Conversely, corticosteroids, danazol, chlorpromazine, and certain asthma medications (e.g., salbutamol) can weaken its effect, leading to higher blood sugar. Always inform your doctor or pharmacist about all other medications, including over-the-counter drugs, herbal remedies, and supplements, you are taking.

What precautions should be taken while on MEFOMIN GZ 80 MG TABLET?

It is crucial to follow your doctor's advice regarding diet and exercise, and to monitor your blood glucose levels regularly. Do not skip or delay meals, as this can increase the risk of low blood sugar (hypoglycemia). Alcohol consumption is not recommended as it can increase the risk of hypoglycemia and other adverse effects. Inform your doctor if you have liver or kidney problems, or if you have a condition called glucose-6-phosphate dehydrogenase (G6PD) deficiency, as these may require dosage adjustments or special monitoring. Be aware of the symptoms of low blood sugar and carry a quick source of sugar (like glucose tablets or fruit juice) with you.

What happens if a dose of MEFOMIN GZ 80 MG TABLET is missed?

If you miss a dose of MEFOMIN GZ 80 MG TABLET, take it as soon as you remember, along with food, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

How should MEFOMIN GZ 80 MG TABLET be stored?

MEFOMIN GZ 80 MG TABLET should be stored at room temperature, typically between 15°C and 30°C. Keep it in a secure location away from excessive heat, moisture, and direct sunlight. Ensure that any leftover or expired medication is disposed of safely.