Ceroxim 250 Mg

Name

• Brand Name: CEROXIM 250 MG Tablet
• Common Name: Cefuroxime (as Cefuroxime Axetil)

Composition CEROXIM 250 MG Tablet contains 250 mg of Cefuroxime, present as cefuroxime axetil. It belongs to the second-generation cephalosporin class of antibiotics.

Uses CEROXIM 250 MG is an antibiotic prescribed for the management of various bacterial infections. It is effective against infections of the:

• Respiratory tract (e.g., bronchitis, pneumonia, sinusitis)
• Throat and tonsils
• Ears (otitis media)
• Skin and soft tissues
• Urinary tract
• Bones and joints
• Uncomplicated gonorrhoea (a sexually transmitted infection)
• Early Lyme disease

It can also be used to prevent infections during surgical procedures.

Dosage and Administration CEROXIM 250 MG Tablet should be taken orally, typically twice daily, and preferably after meals to enhance absorption and minimize stomach upset. The tablets should be swallowed whole and not crushed or chewed. The usual course of treatment ranges from 5 to 10 days, but it may extend depending on the infection's type and severity. Completing the full prescribed course is crucial to prevent antibiotic resistance and recurrence of infection.

Side Effects Common side effects may include:

• Headache, dizziness
• Diarrhoea, nausea, vomiting, stomach pain/upset
• Fungal infections (e.g., candidiasis)
• Increased liver enzymes
• Rash

Serious, though less common, side effects include severe persistent diarrhoea (Clostridioides difficile-associated diarrhoea) and neurological disorders such as seizures, particularly in cases of overdose.

Precautions

• Inform your doctor if you have known allergies to cefuroxime, other cephalosporin antibiotics, or any penicillin-class antibiotics.
• Use with caution in patients with kidney or liver problems; dosage adjustments may be necessary for kidney impairment.
• CEROXIM 250 MG may reduce the effectiveness of oral contraceptives.
• Antacids containing aluminum and magnesium salts may reduce its absorption; take CEROXIM 250 MG at least 1-2 hours apart from antacids.
• This medicine may cause dizziness, so caution is advised when driving or operating machinery.
• Pregnant or breastfeeding individuals should consult their doctor before use.

Storage Store CEROXIM 250 MG Tablets in a cool, dry place, protected from direct sunlight, moisture, and heat, at or below 30°C (or between 10°C to 25°C). Keep out of the reach of children.

Here are some frequently asked questions about CEROXIM 250 MG by SUN PHARMA LABORATORIES LTD., which contains the active ingredient Cefuroxime:

What is Ceroxim 250 mg used for?

Ceroxim 250 mg is an antibiotic used to treat a variety of bacterial infections in different parts of the body. These include infections of the respiratory tract (such as bronchitis, pneumonia, sinus infections, and throat infections), urinary tract infections, skin and soft tissue infections, ear infections (otitis media), and early Lyme disease. It is important to note that Ceroxim 250 mg only works against bacterial infections and will not be effective for viral infections like the common cold or flu.

How does Ceroxim 250 mg work?

Ceroxim 250 mg contains Cefuroxime, a second-generation cephalosporin antibiotic. It works by interfering with the formation of bacterial cell walls. By binding to specific proteins inside the bacterial cell wall, it inhibits cell wall synthesis, causing the cell walls to rupture and ultimately leading to the death of the bacteria.

What is the usual dosage of Ceroxim 250 mg?

The usual adult dosage of Ceroxim 250 mg (cefuroxime tablets) for many infections is 250 mg every 12 hours for 5 to 10 days, depending on the specific infection being treated and its severity. For certain conditions like early Lyme disease or more severe infections, a higher dosage such as 500 mg every 12 hours might be prescribed. It's crucial to follow your doctor's specific instructions regarding dosage and duration.

What are the possible side effects of Ceroxim 250 mg?

Common side effects of Ceroxim 250 mg can include diarrhea, nausea, vomiting, stomach cramps, and headache. Less common but possible side effects include vaginal yeast infections and elevated liver enzymes. Serious but rare side effects can include severe allergic reactions (symptoms like hives, difficulty breathing, or swelling of the face, lips, tongue, or throat) and Clostridioides difficile-associated diarrhea (severe, watery, or bloody diarrhea). If you experience any severe or persistent side effects, contact your doctor immediately.

Is Ceroxim 250 mg safe during pregnancy or breastfeeding?

Pregnancy: Cefuroxime is generally considered safe during pregnancy and is classified as an FDA pregnancy category B drug. Animal studies have shown no evidence of harm to the fetus. However, there are no adequate and well-controlled studies in pregnant women, so it should be used during pregnancy only if clearly needed and under a doctor's guidance.

Breastfeeding: Cefuroxime is excreted in human milk in low levels, which are generally not expected to cause severe adverse effects in breastfed infants. However, there's a potential for altering the infant's gut flora, which could lead to diarrhea or thrush. Caution is advised, and monitoring the infant for any adverse effects like diarrhea, thrush, or rash is recommended.

Can Ceroxim 250 mg be taken with other medications?

Ceroxim 250 mg can interact with certain medications. It is important to inform your doctor about all prescription drugs, over-the-counter medicines, vitamins, and herbal supplements you are taking.

• Antacids containing magnesium or aluminum can reduce the absorption of cefuroxime. If you take them, do so at least 1 hour before or 2 hours after Ceroxim 250 mg.
• Oral contraceptives (birth control pills) may have their effectiveness decreased by cefuroxime, so alternative birth control methods should be considered.
• Blood thinners like warfarin may have their effects enhanced, potentially increasing the risk of bleeding.
• Probenecid (used for gout) can increase the concentration of cefuroxime in the blood.

What precautions should be taken when taking Ceroxim 250 mg?

• Allergies: Inform your doctor if you have ever had an allergic reaction to cefuroxime, other cephalosporins, or penicillin antibiotics.
• Medical Conditions: Discuss any history of kidney disease, liver disease, or gastrointestinal problems, especially colitis, with your doctor, as dosage adjustments or careful monitoring may be necessary.
• Complete the Course: It is crucial to complete the entire prescribed course of Ceroxim 250 mg, even if your symptoms improve sooner. Stopping the medication too early can lead to the infection returning and may contribute to antibiotic resistance.
• Tablets vs. Suspension: Do not switch between tablets and oral liquid suspension without your doctor's guidance, as they are absorbed differently. Swallow tablets whole; do not crush or chew them.

What happens if a dose of Ceroxim 250 mg is missed?

If you miss a dose of Ceroxim 250 mg, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this could lead to increased side effects.

How should Ceroxim 250 mg be stored?

Ceroxim 250 mg tablets should be stored in a closed container at room temperature, away from heat, moisture, and direct light. Keep them out of the reach of children. If you have the oral suspension, it should generally be stored in the refrigerator after reconstitution and any unused portion should be discarded after 10 days. Do not freeze the oral liquid, as it may become less effective.