Signoflam Th 4 Tablet (10 Tab)

SIGNOFLAM TH 4 TABLET

SIGNOFLAM TH 4 TABLET, manufactured by LUPIN LTD, is a combination medication used to manage pain, inflammation, and muscle spasms.

Composition Each tablet contains a blend of three active ingredients:

• Aceclofenac (100 mg): A non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking chemical messengers.
• Paracetamol (325 mg): An analgesic and antipyretic that helps relieve pain and reduce fever.
• Thiocolchicoside (4 mg): A muscle relaxant that acts on the central nervous system to relieve muscle stiffness and improve movement.

Uses SIGNOFLAM TH 4 TABLET is prescribed for the relief of pain and inflammation associated with various musculoskeletal and joint disorders. These include osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, bone and joint pain, lower back pain, neck and shoulder pain, sciatica, and degenerative vertebral disorders. It also helps in managing post-operative pain and inflammation.

Dosage and Administration Take SIGNOFLAM TH 4 TABLET as directed by your doctor. It is advisable to swallow the tablet whole with a glass of water, without crushing, chewing, or breaking it. To minimize stomach upset, it is recommended to take this medicine with food. The dosage and duration of treatment will depend on your medical condition and should not exceed the recommended dose.

Side Effects Common side effects may include nausea, vomiting, stomach pain, loss of appetite, heartburn, diarrhea, dizziness, drowsiness, and increased liver enzymes. Serious side effects, such as severe allergic reactions, severe skin reactions, or signs of gastrointestinal bleeding, require immediate medical attention.

Precautions This medicine is not recommended for individuals with known allergies to its components or other NSAIDs, severe liver or kidney disease, peptic ulcers or intestinal bleeding, certain heart problems, bleeding disorders, severe asthma, or for pregnant or breastfeeding women. Alcohol consumption should be avoided as it can increase drowsiness and the risk of stomach bleeding and liver damage. SIGNOFLAM TH 4 TABLET may cause dizziness and drowsiness, so caution is advised when driving or operating machinery. It should not be given to children as its safety and efficacy have not been established. Caution is also advised for elderly patients and those with certain pre-existing medical conditions.

Storage Store SIGNOFLAM TH 4 TABLET below 30°C. Keep it out of reach and sight of children.

What is Signoflam TH 4 Tablet used for?

Signoflam TH 4 Tablet is a combination medicine primarily used to relieve pain and inflammation associated with musculoskeletal and joint conditions. These conditions include osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, lower back pain, muscle spasms due to injury, neck and shoulder pain, and sciatica. It also helps in managing acute inflammatory conditions and improving muscle movement.

How does Signoflam TH 4 Tablet work?

Signoflam TH 4 Tablet contains three active ingredients: Aceclofenac, Paracetamol (Acetaminophen), and Thiocolchicoside. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the production of prostaglandins, chemicals in the body responsible for pain and inflammation. Paracetamol is an analgesic and antipyretic that helps reduce pain and fever by inhibiting prostaglandin synthesis in the brain. Thiocolchicoside is a muscle relaxant that acts on the central nervous system, specifically the spinal cord and brain, to relieve muscle stiffness and spasms, thereby improving muscle movements.

What is the usual dosage of Signoflam TH 4 Tablet?

The dosage of Signoflam TH 4 Tablet is determined by your doctor based on individual factors such as the severity of your condition, age, body weight, and response to treatment. It is usually advised to take one tablet, typically up to three times daily, with or after meals to avoid stomach upset. You should swallow the tablet whole with a glass of water and not crush or chew it. It's important to follow the prescribed dosage and duration and not exceed it without consulting your doctor. Prolonged use beyond 7 days is generally not recommended.

What are the possible side effects of Signoflam TH 4 Tablet?

While generally considered safe and effective when taken as directed, Signoflam TH 4 Tablet can cause some side effects. Common side effects may include nausea, vomiting, stomach pain, indigestion, heartburn, diarrhea, loss of appetite, dizziness, and drowsiness. Some individuals may also experience visual disturbances. If these side effects persist or worsen, it's important to consult your doctor. Serious side effects are rare but can include severe allergic reactions, severe skin reactions, or gastrointestinal bleeding.

Is Signoflam TH 4 Tablet safe during pregnancy or breastfeeding?

Signoflam TH 4 Tablet is generally not recommended for use in pregnant or breastfeeding women. The components of this medicine may cause abnormalities in the unborn baby or pass into breast milk in small amounts, potentially harming the baby. It should only be taken if the potential benefits outweigh the risks, and only under strict medical advice. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can Signoflam TH 4 Tablet be taken with other medications?

Signoflam TH 4 Tablet can interact with various medications. It may reduce the effect of anti-hypertensives (e.g., losartan, enalapril), increase the risk of nephrotoxicity with diuretics (e.g., furosemide), and enhance the effects of anticoagulants like warfarin, increasing the risk of bleeding. Concomitant use with other NSAIDs or aspirin can increase adverse reactions, including gastrointestinal bleeding. It may also interact with anti-diabetic medications, anti-HIV medicines (e.g., zidovudine), and certain medicines for nausea or vomiting (e.g., metoclopramide, domperidone). Always inform your doctor about all prescription, over-the-counter, and herbal medicines you are taking to avoid potential interactions.

What precautions should be taken while using Signoflam TH 4 Tablet?

Several precautions should be observed when taking Signoflam TH 4 Tablet. It is not recommended for individuals with severe kidney or liver impairment, peptic ulcers, intestinal bleeding, bleeding disorders, or certain heart conditions (e.g., heart attack, stroke). Caution is advised in patients with a history of stomach ulcers, asthma, or blood disorders. Alcohol consumption should be avoided as it can increase drowsiness and the risk of liver damage and stomach bleeding. Due to potential dizziness or drowsiness, avoid driving or operating machinery if you experience these side effects. Elderly patients may be more susceptible to side effects.

What happens if a dose of Signoflam TH 4 Tablet is missed?

If you miss a dose of Signoflam TH 4 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing pattern. Do not take a double dose to compensate for the missed one. Always consult your doctor before making any changes to your dosage.

How should Signoflam TH 4 Tablet be stored?

Signoflam TH 4 Tablet should be stored at room temperature, typically between 20-25°C. It is important to protect the tablets from moisture and light. Keep the medicine out of the reach and sight of children.