Dulot 30 Mg Tablet (10 Tab)

DULOT 30 MG TABLET by LUPIN LTD.

Name

Brand Name: Dulot 30 Tablet Common Name: Duloxetine (30 mg)

Composition

DULOT 30 MG TABLET contains 30 mg of Duloxetine as its active ingredient. Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant.

Uses

DULOT 30 MG TABLET is prescribed for the treatment of various medical conditions, including:

• Depression
• Anxiety disorder
• Diabetic nerve pain (diabetic neuropathic pain)
• Fibromyalgia
• Neuropathic pain
• Stress urinary incontinence in women

Dosage and Administration

This medicine should be taken in the dose and duration as advised by your doctor. DULOT 30 MG TABLET can be taken with or without food, but it is recommended to take it at a fixed time daily to maintain consistent blood levels. Swallow the tablet whole; do not chew, crush, or break it. Do not stop taking the medication suddenly without consulting your doctor, as this may lead to withdrawal symptoms and worsen your condition.

Side Effects

Common Side Effects:

• Nausea
• Headache
• Dry mouth
• Sleepiness/Dizziness
• Decreased libido (sex drive)
• Blurred vision
• Abnormal dreams
• Constipation or diarrhea
• Fatigue

Serious Side Effects (Seek immediate medical attention if you experience):

• Thoughts of harming or killing yourself
• Signs of liver damage (dark urine, yellowing of skin/eyes, pain in the upper right abdomen)
• Significant changes in blood pressure
• Agitation, tremors, seizures, or hallucinations
• Severe skin reactions (rashes, peeling skin, blisters)

Precautions

• Alcohol: Avoid consuming alcohol with DULOT 30 MG TABLET as it may increase drowsiness and the risk of liver damage.
• Pregnancy & Breastfeeding: Consult your doctor. DULOT 30 MG TABLET may be unsafe during pregnancy and is probably unsafe during breastfeeding as it may pass into breast milk.
• Driving & Operating Machinery: This medicine may cause dizziness and sleepiness. Do not drive or perform activities requiring mental focus until you understand how it affects you.
• Medical Conditions: Inform your doctor if you have kidney, heart, or liver problems, a history of seizures (epilepsy or fits), mania, bipolar disorder, glaucoma, low sodium levels, or a bleeding disorder.
• Sudden Stoppage: Do not stop taking this medication suddenly without consulting your doctor, as it can lead to withdrawal symptoms.
• Suicidal Thoughts: Monitor for sudden mood changes or the development of suicidal thoughts, especially when first starting the medication or during dose adjustments.

Storage

Store DULOT 30 MG TABLET below 30°C in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children.

DULOT 30 MG TABLET contains duloxetine, which is an antidepressant medication. It's used to treat a variety of conditions by affecting certain chemical messengers in the brain.

Here are some frequently asked questions about DULOT 30 MG TABLET:

What is DULOT 30 MG TABLET used for?

DULOT 30 MG TABLET is primarily used to treat major depressive disorder and generalized anxiety disorder in adults. It is also prescribed for chronic pain conditions such as diabetic nerve pain (diabetic peripheral neuropathic pain), fibromyalgia, neuropathic pain, and chronic musculoskeletal pain. Additionally, it can be used to treat stress urinary incontinence in women.

How does DULOT 30 MG TABLET work?

DULOT 30 MG TABLET works by increasing the levels of certain natural chemical messengers in the brain, namely serotonin and noradrenaline (also known as norepinephrine). These chemicals play a crucial role in maintaining mental balance and stopping the movement of pain signals in the brain, leading to a calming effect, improved mood, and reduced pain. It also increases dopamine specifically in the prefrontal cortex by inhibiting noradrenaline reuptake.

What is the usual dosage for DULOT 30 MG TABLET?

The dosage of DULOT 30 MG TABLET depends on the condition being treated and is determined by your doctor. For depression and anxiety, a common starting dose is 30 mg once daily, which may be increased to 60 mg once daily. For nerve pain, a starting dose of 60 mg once daily is typical, potentially increasing to 60 mg twice daily. For stress urinary incontinence, a common starting dose is 20 mg twice daily, which can be increased to 40 mg twice daily after two weeks. It's advised to take the medicine at a fixed time each day, with or without food, and swallow the tablet whole without chewing or crushing it.

What are the possible side effects of DULOT 30 MG TABLET?

Common side effects include nausea, headache, dry mouth, sleepiness, dizziness, fatigue, constipation, decreased libido, abnormal dreams, and increased sweating. Some people may also experience blurred vision or a sensation of restlessness. More serious but less common side effects can include liver damage, changes in blood pressure, serotonin syndrome (agitation, confusion, sweating, loss of coordination), abnormal bleeding, severe skin reactions, seizures, and low sodium levels. If any side effects persist or worsen, consult your doctor.

Is DULOT 30 MG TABLET safe during pregnancy or breastfeeding?

DULOT 30 MG TABLET may be unsafe during pregnancy. While there are limited human studies, animal studies have shown potential harmful effects on the developing baby. Your doctor will weigh the benefits and potential risks before prescribing it during pregnancy. If taken in the weeks before birth, it can sometimes cause short-term withdrawal symptoms and, rarely, breathing problems in the baby. It is generally not recommended during breastfeeding as it may pass into breast milk and potentially harm the baby. However, some expert opinions suggest it may be acceptable with caution, with monitoring of the infant for drowsiness and adequate feeding. It's crucial to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can DULOT 30 MG TABLET be taken with other medications?

DULOT 30 MG TABLET can interact with other medications, and it's essential to inform your doctor about all prescription, over-the-counter drugs, herbal supplements, and vitamins you are taking. It should not be taken with MAO inhibitors (a class of antidepressants) or within two weeks of discontinuing them due to the risk of life-threatening complications. Taking it with other antidepressants can increase the risk of serotonin syndrome. The risk of bleeding may increase if taken with blood thinners (anticoagulants, antiplatelets) or nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin or ibuprofen.

What precautions should be taken with DULOT 30 MG TABLET?

Avoid consuming alcohol while taking DULOT 30 MG TABLET, as it can increase drowsiness and the risk of liver damage. This medicine can cause dizziness and sleepiness, so do not drive or operate heavy machinery until you know how it affects you. Inform your doctor if you have kidney, heart, or liver problems, a history of seizures, glaucoma, diabetes, or a bleeding disorder. Monitor for sudden mood changes or suicidal thoughts, especially when starting treatment. Do not stop taking the medication suddenly without consulting your doctor, as it can lead to withdrawal symptoms and worsen your condition.

What happens if a dose is missed?

If you miss a dose of DULOT 30 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should DULOT 30 MG TABLET be stored?

DULOT 30 MG TABLET should be stored in a cool and dry place, below 30°C, away from direct sunlight. Keep it out of sight and reach of children.