Tri Azulix Ds 2 Mg Tablet (10 Tab)

TRI AZULIX DS 2 MG TABLET

Name

Brand Name: TRI AZULIX DS 2 MG TABLET, Tri-Azulix DS 2 Tablet SR Manufacturer: Torrent Pharmaceuticals Ltd.

Composition

Each tablet contains a combination of three active ingredients:

• Glimepiride: 2 mg
• Metformin (as Metformin Hydrochloride): 500 mg
• Pioglitazone: 15 mg

Uses

TRI AZULIX DS 2 MG TABLET is prescribed for the management of type 2 diabetes mellitus. It is used when diet, exercise, and single-agent therapy (like Glimepiride or Metformin alone) are not sufficient to achieve adequate blood sugar control. This medication helps lower both fasting and post-meal blood glucose levels, thereby reducing the risk of diabetes-related complications such as heart disease, kidney damage, nerve problems, and blindness.

Dosage and Administration

This medicine should be taken orally, usually once daily with meals, or as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water and not crushed or chewed. Dosage is individualized based on the patient's medical condition and response to treatment.

Side Effects

Common side effects include:

• Hypoglycemia (low blood sugar levels)
• Nausea, vomiting, diarrhea, stomach pain
• Headache, dizziness
• Weight gain
• Upper respiratory tract infections
• Blurred vision

Serious side effects, though less common, can include:

• Lactic acidosis (symptoms like cold hands/feet, unusual muscle pain, trouble breathing, severe tiredness)
• Symptoms of heart failure (unusual shortness of breath, rapid weight increase, swelling in ankles or legs)

Precautions

• Contraindications: Not recommended for patients with severe heart failure (Class III or IV), serious kidney or liver failure, metabolic acidosis, type 1 diabetes mellitus, bladder cancer, or known allergy to any of its components.
• Pregnancy and Breastfeeding: Not recommended during pregnancy or breastfeeding.
• Alcohol: Avoid or limit alcohol consumption, as it can increase the risk of hypoglycemia and lactic acidosis.
• Driving: May cause dizziness or blurred vision due to low blood sugar; caution is advised when driving or operating machinery.
• Drug Interactions: Inform your doctor about all other medications, including over-the-counter and herbal products, to avoid potential interactions.

Storage

Store the medicine below 30°C. Protect it from moisture and light. Keep it out of the reach and sight of children.

What is TRI AZULIX DS 2 MG TABLET used for?

TRI AZULIX DS 2 MG TABLET is primarily used for the management of type 2 diabetes mellitus in adults. It helps to control high blood sugar levels when diet, exercise, and treatment with a single antidiabetic agent or a dual combination of medicines are not sufficient. The medication aims to lower both fasting and post-meal blood glucose levels, thereby helping to prevent or delay serious complications associated with diabetes, such as heart disease, kidney damage, nerve problems, blindness, and limb amputations.

How does TRI AZULIX DS 2 MG TABLET work?

TRI AZULIX DS 2 MG TABLET is a combination of three antidiabetic medicines: Glimepiride, Metformin, and Pioglitazone, which work together through different mechanisms to improve blood sugar control.

• Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin. Insulin helps move sugar (glucose) from the blood into the cells for energy.
• Metformin is a biguanide that reduces the production of glucose by the liver and decreases its absorption from the intestine. It also enhances the body's sensitivity to insulin.
• Pioglitazone is a thiazolidinedione that improves the sensitivity of liver, muscle, and fat tissues to insulin, allowing the body's cells to use blood glucose more effectively and reducing insulin resistance.

What are the active ingredients in TRI AZULIX DS 2 MG TABLET?

TRI AZULIX DS 2 MG TABLET contains three active ingredients: Glimepiride (2 mg), Metformin (500 mg), and Pioglitazone (15 mg).

What is the usual dosage of TRI AZULIX DS 2 MG TABLET?

TRI AZULIX DS 2 MG TABLET should be taken in the dose and duration as advised by your doctor. It is typically taken orally, usually once daily with meals, or as directed by your physician. The exact dosage is based on your medical condition and response to treatment. It is crucial to swallow the tablet whole with a glass of water and not to crush or chew it.

What are the possible side effects of TRI AZULIX DS 2 MG TABLET?

Common side effects of TRI AZULIX DS 2 MG TABLET include:

• Hypoglycemia (low blood sugar levels), which can manifest as sweating, trembling, dizziness, confusion, or a fast heartbeat.
• Nausea or vomiting
• Diarrhea
• Headache
• Stomach pain or upset
• Dizziness
• Weight gain
• Upper respiratory tract infections or sinus infection
• Metallic taste in the mouth
• Muscle pain or joint pain Most of these side effects are temporary and usually resolve over time. However, if any side effects persist or worsen, it is important to consult your doctor.

Is TRI AZULIX DS 2 MG TABLET safe during pregnancy or breastfeeding?

TRI AZULIX DS 2 MG TABLET is generally not recommended for use during pregnancy as it may cause harm to the unborn baby.

For breastfeeding mothers, caution is advised, and it is generally considered unsafe or not recommended, as the components may be excreted in human milk and potentially cause adverse effects in the baby. It is important to consult your doctor for suitable alternatives if you are pregnant, planning a pregnancy, or breastfeeding.

Can TRI AZULIX DS 2 MG TABLET be taken with other medications?

TRI AZULIX DS 2 MG TABLET can interact with various other medicines, supplements, or herbal products. It is crucial to inform your doctor about all medications you are currently taking or might take, including prescription, over-the-counter, and herbal products, to avoid possible interactions. Some medications that may interact include other blood sugar medicines (like insulin or glibenclamide), heart medicines, blood pressure medicines, antibiotics, painkillers, certain antidepressants, blood thinners, and antacids. For instance, specific medications like prednisolone, epinephrine, and norepinephrine may reduce the effectiveness of Tri Azulix DS 2 MG Tablet.

What precautions should be taken while using TRI AZULIX DS 2 MG TABLET?

Several precautions should be taken while using TRI AZULIX DS 2 MG TABLET:

• Alcohol Consumption: It is strongly advised to avoid or limit alcohol consumption during treatment as it can increase the risk of low blood sugar (hypoglycemia) and serious complications like lactic acidosis.
• Driving and Operating Machinery: This medicine can cause low blood sugar levels, leading to drowsiness, dizziness, visual disturbances, or confusion, which can impair your ability to drive or operate machinery. Exercise caution and monitor your blood sugar regularly.
• Pre-existing Conditions: Inform your doctor if you have any history of kidney disease, liver disease, heart problems (especially heart failure), bladder cancer, or eye disorders/visual disturbances, as this medicine may not be suitable or may require careful monitoring.
• Diet and Exercise: This medication works best when combined with a healthy diet and regular exercise, as advised by your doctor.
• Hypoglycemia Management: Always carry a fast-acting source of sugar (like glucose tablets, fruit juice, or candy) to treat sudden low blood sugar episodes.
• Monitoring: Regular monitoring of blood sugar levels is essential. Your doctor may also recommend regular checks of kidney and liver function.

What happens if a dose of TRI AZULIX DS 2 MG TABLET is missed?

If you miss a dose of TRI AZULIX DS 2 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one, as this can increase the risk of low blood sugar (hypoglycemia).

How should TRI AZULIX DS 2 MG TABLET be stored?

TRI AZULIX DS 2 MG TABLET should be stored at room temperature (20-25°C) and protected from moisture and light. Keep it out of the reach and sight of children.