Huminsulin R 40iu Injection 10 Ml (vial)

HUMINSULIN R 40IU INJECTION 10 ML (VIAL)

Huminsulin R 40IU Injection is a short-acting insulin medication manufactured by Lupin Ltd., primarily used for managing diabetes mellitus. It provides rapid and consistent sugar control by mimicking the body's natural insulin action.

Composition

Each ml of Huminsulin R 40IU Injection contains:

• Active Ingredient: Human Insulin (r-DNA origin) 40 IU
• Other Ingredients: m-Cresol Ph. Eur. 2.5 mg, Glycerin 16 mg, Hydrochloric acid q.s., Sodium hydroxide q.s., and Water for Injection 1 ml.

Uses

Huminsulin R Injection is prescribed for the management of:

• Type 1 Diabetes Mellitus: It replaces the deficient insulin that the body no longer produces.
• Type 2 Diabetes Mellitus: It is used to control high blood sugar levels when oral antidiabetic drugs are insufficient or contraindicated.
• Maintaining Normal Glucose Homeostasis: Helps in maintaining balanced blood sugar levels throughout the day.
• Control of Post-Prandial Glucose Excursions: Acts quickly to manage spikes in blood sugar after meals.

Dosage and Administration

Huminsulin R Injection is administered subcutaneously (under the skin) 20 to 30 minutes before a meal.

• Injection Sites: Administer into the thigh, upper arm, abdomen, or buttock.
• Rotation: Rotate injection sites to avoid skin changes and irritation such as lipodystrophy.
• Dosage: The daily dosage is determined by a healthcare professional based on individual needs and response to treatment. Do not self-adjust the dosage.

Side Effects

Common side effects include:

• Hypoglycemia (low blood sugar): Characterized by sweating, shaking, blurred vision, irregular heartbeat, hunger, tremors, anxiety, and fatigue.
• Injection site reactions: Redness, swelling, discomfort, or pain at the injection site.
• Lipodystrophy: Changes in body fat, such as thickening or thinning of skin at the injection area, due to repeated injections in the same spot.
• Weight gain
• Edema (swelling of face, hands and legs)

Precautions

• Hypoglycemia: Be vigilant for symptoms of low blood sugar, especially if meals are missed or delayed, alcohol is consumed, or excessive exercise is performed.
• Pregnancy and Breastfeeding: Generally considered safe if prescribed, but consult a doctor for dose adjustments and monitoring.
• Liver and Kidney Disease: Use with caution; dose adjustments and close monitoring of blood sugar levels may be necessary.
• Alcohol: Avoid or limit alcohol consumption as it can significantly affect blood sugar levels.
• Drug Interactions: Inform your doctor about all other medications, including anti-diabetic agents, blood pressure medications, corticosteroids, and thyroid hormones, as they can interact with insulin and affect blood sugar levels.
• Driving and Operating Machinery: May cause dizziness or blurred vision due to fluctuations in blood sugar, so exercise caution.

Storage

• Unopened Vials: Store in a refrigerator between 2°C to 8°C (36°F to 46°F). Do not freeze.
• Opened Vials: Once opened, the vial can be kept at room temperature (below 30°C or 86°F) for up to 28 days.
• Protection: Keep away from direct heat, light, and out of reach of children.
• Expiry: Always check the expiry date and use the product before this date.

Here are some frequently asked questions about HUMINSULIN R 40IU INJECTION 10 ML (VIAL) by LUPIN LTD.

What is HUMINSULIN R 40IU INJECTION used for?

HUMINSULIN R 40IU INJECTION is a short-acting insulin used to treat both Type 1 and Type 2 diabetes mellitus. It helps control blood sugar levels, especially after meals, and reduces the risk of serious diabetes complications like kidney damage, eye damage, and nerve problems. It is often prescribed alongside a long-acting insulin or other diabetes medications.

How does HUMINSULIN R 40IU INJECTION work?

This medicine contains Human Insulin, which works similarly to the insulin naturally produced by the body. It facilitates the uptake of sugar (glucose) by muscle and fat cells for energy and suppresses the production of glucose in the liver. HUMINSULIN R 40IU INJECTION typically starts working within 30 minutes after injection, and its effect can last up to 8 hours.

What is the usual dosage for HUMINSULIN R 40IU INJECTION?

The dosage of HUMINSULIN R INJECTION is individualized by your doctor based on your specific needs, blood sugar monitoring results, and treatment goals. It is administered as a subcutaneous injection (under the skin) in areas like the abdomen, thigh, or upper arm, usually 20 to 30 minutes before a meal. Always follow your doctor's instructions for the correct dosage and administration technique.

What are the possible side effects of HUMINSULIN R 40IU INJECTION?

The most common side effect is hypoglycemia (low blood sugar), which can cause symptoms like sweating, anxiety, shakiness, hunger, fast heart rate, and headache. Other common side effects include injection site reactions such as redness, itching, pain, and swelling. Weight gain and lipodystrophy (changes in fat tissue at the injection site due to repeated injections in the same area) can also occur.

Is HUMINSULIN R 40IU INJECTION safe during pregnancy or breastfeeding?

Yes, HUMINSULIN R 40IU INJECTION is generally considered safe for use during pregnancy if prescribed by a doctor. Close monitoring of blood sugar levels is important, as dosage requirements may change during pregnancy. It is also safe to use during breastfeeding, as insulin passes into breast milk in very small amounts and is unlikely to harm the baby.

Can HUMINSULIN R 40IU INJECTION be taken with other medications?

Many medications can interact with HUMINSULIN R INJECTION, affecting blood sugar levels and potentially requiring dosage adjustments. Inform your doctor about all prescription, over-the-counter drugs, supplements, and herbal products you are taking. Examples of medications that may interact include other antidiabetic agents, corticosteroids, thyroid hormones, certain antipsychotics, beta-blockers, and aspirin.

What precautions should be taken with HUMINSULIN R 40IU INJECTION?

It is crucial to rotate injection sites to prevent skin damage like lipodystrophy. Avoid consuming alcohol, as it can affect blood sugar levels and increase the risk of hypoglycemia. Regular monitoring of blood sugar levels is essential, and carry sugary snacks to treat hypoglycemia if it occurs. Inform your doctor if you have kidney, liver, or heart problems, as dose adjustments or extra caution may be needed. Never share needles or syringes with anyone else.

What happens if a dose of HUMINSULIN R 40IU INJECTION is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one, as this can lead to a drastic and dangerous fall in blood glucose levels. Consult your doctor for guidance if you are unsure.

How should HUMINSULIN R 40IU INJECTION be stored?

Unopened vials of HUMINSULIN R INJECTION should be stored in a refrigerator at a temperature between 2°C to 8°C (36°F to 46°F). Do not freeze the medicine, and do not use it if it has been frozen. Once an opened vial is in use, it can be kept at room temperature (below 30°C or 86°F) for up to 28 days, after which it should be discarded, even if it still contains medicine. Keep it away from direct heat and light, and out of reach of children.