Siaglide 100 Mg Tab

SIAGLIDE 100 MG TABLET

SIAGLIDE 100 MG TABLET is a medication manufactured by ABBOTT HEALTHCARE LTD-QUANTUS DIV, primarily used for the management of Type 2 Diabetes Mellitus.

• Name:

  • Common Name: Sitagliptin 100mg Tablet
  • Brand Name: SIAGLIDE 100 MG TABLET. (Sitagliptin is also available under the brand name Januvia)

• Composition:

  • Active Ingredient: Sitagliptin 100mg.

• Uses: SIAGLIDE 100 MG TABLET is prescribed as an adjunct to diet and exercise to improve glycemic control in adults with Type 2 Diabetes Mellitus. It helps to lower high blood sugar levels by increasing insulin levels in the body and reducing the amount of sugar released into the blood. This medication is not used to treat Type 1 diabetes or diabetic ketoacidosis.

• Dosage and Administration: The recommended dose for adults is 100 mg once daily. It can be taken with or without food, preferably at the same time each day. The tablet should be swallowed whole and not split, crushed, or chewed. Dosage adjustments are necessary for patients with renal impairment: 50 mg once daily for moderate kidney impairment and 25 mg once daily for severe kidney impairment or end-stage renal disease (ESRD) requiring dialysis.

• Side Effects:

  • Common Side Effects: Upset stomach, diarrhea, stomach pain, upper respiratory infection, stuffy or runny nose, sore throat, and headache.
  • Serious Side Effects: Pancreatitis (severe and persistent stomach pain, sometimes radiating to the back, with or without vomiting), severe allergic reactions (rash, hives, swelling of face, lips, tongue, and throat, difficulty breathing or swallowing), severe and disabling joint pain, kidney problems (swelling of feet, ankles, or legs, decreased urine amount), and bullous pemphigoid (large, fluid-filled blisters). Low blood sugar (hypoglycemia) can occur, especially when taken with other diabetes medications.

• Precautions: Before taking SIAGLIDE, inform your doctor about any history of pancreatitis, kidney problems, gallstones, alcoholism, or high triglyceride levels. It's important to monitor blood sugar levels regularly. Caution should be exercised in pregnant or breastfeeding women. Patients should be aware of the symptoms of low blood sugar and how to treat it. Alcohol consumption should be limited as it can increase the risk of low blood sugar.

• Storage: Store SIAGLIDE 100 MG TABLET at room temperature, typically between 20°C to 25°C (68°F to 77°F). Keep it in a closed container, away from excessive heat, moisture, and direct light, and out of the reach of children.

What is SIAGLIDE 100 MG TAB used for?

SIAGLIDE 100 MG TAB, which contains Sitagliptin, is used to improve blood sugar control in adults with type 2 diabetes mellitus. It is typically prescribed as an add-on to diet and exercise when lifestyle changes alone are not enough to manage blood sugar levels. It is not used to treat type 1 diabetes or diabetic ketoacidosis.

How does SIAGLIDE 100 MG TAB work?

SIAGLIDE 100 MG TAB belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by blocking the DPP-4 enzyme, which normally breaks down natural hormones called incretins (GLP-1 and GIP). By inhibiting DPP-4, Sitagliptin increases the levels of these incretin hormones, leading to an increase in insulin production by the pancreas (especially after meals) and a decrease in glucagon production by the liver. This glucose-dependent action helps to lower high blood sugar levels.

What is the usual dosage for SIAGLIDE 100 MG TAB?

The recommended dosage for SIAGLIDE 100 MG TAB is one 100 mg tablet taken orally once daily. It can be taken with or without food, but it is advised to take it at roughly the same time each day. Your doctor may adjust the dosage if you have kidney problems: 50 mg once daily for moderate kidney impairment and 25 mg once daily for severe kidney impairment or end-stage renal disease (including those on dialysis).

What are the possible side effects of SIAGLIDE 100 MG TAB?

Common side effects may include headaches, stuffy or runny nose, sore throat, upper respiratory tract infection, nausea, diarrhea, and stomach pain.

Serious side effects, though rare, can occur. These include severe stomach pain (possibly indicating pancreatitis), severe allergic reactions (e.g., rash, hives, swelling of the face, lips, tongue, or throat, difficulty breathing), low blood sugar (especially when taken with other diabetes medications), kidney problems, heart failure (symptoms like shortness of breath, swelling in ankles/feet, sudden weight gain), and severe joint pain. You should contact your doctor immediately if you experience any serious side effects.

Is SIAGLIDE 100 MG TAB safe during pregnancy or breastfeeding?

Pregnancy: SIAGLIDE 100 MG TAB is generally not recommended during pregnancy due to limited information on its potential effects on a developing baby. If you are pregnant or planning to become pregnant, you should discuss alternative treatments with your doctor.

Breastfeeding: It is usually not recommended while breastfeeding as it's not clear how much of the medication passes into breast milk. An alternative medication may be preferred, especially for newborns or premature infants. If you are breastfeeding, consult your doctor, who may advise monitoring the infant's blood glucose.

Can SIAGLIDE 100 MG TAB be taken with other medications?

SIAGLIDE 100 MG TAB can be taken with other diabetes medications such as metformin, sulfonylureas, or insulin. However, combining it with insulin or sulfonylureas may increase the risk of low blood sugar, and your doctor might need to adjust the dosage of those medications.

Other medications can also interact with Sitagliptin. For example, some antibiotics, beta-blockers, ACE inhibitors, digoxin, corticosteroids, and diuretics may affect blood sugar levels or increase the risk of certain side effects like angioedema. It is crucial to inform your doctor about all prescription and non-prescription medications, vitamins, and herbal supplements you are taking.

What precautions should be taken while taking SIAGLIDE 100 MG TAB?

Before taking SIAGLIDE 100 MG TAB, inform your doctor about any allergies you have, or if you have a history of pancreatitis, kidney disease, heart failure, gallstones, high triglyceride levels, or alcohol dependency.

You should regularly monitor your blood sugar levels and carefully follow any diet and exercise recommendations from your doctor. Do not stop taking the medication without consulting your doctor, even if you feel well. Be aware of the symptoms of both high and low blood sugar. If you are undergoing surgery, including dental procedures, inform your healthcare provider that you are taking Sitagliptin.

What happens if a dose of SIAGLIDE 100 MG TAB is missed?

If you miss a dose of SIAGLIDE 100 MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should SIAGLIDE 100 MG TAB be stored?

SIAGLIDE 100 MG TAB should be stored in its closed container at room temperature, typically between 68°F to 77°F (20°C to 25°C), and kept away from heat, moisture, and direct light. It is important to keep this medicine out of the reach of children and to avoid freezing it.