Rexipra Plus Tab

REXIPRA PLUS TABLET by INTAS PHARMACEUTICALS LTD

Name: Rexipra Plus Tablet

Composition: Each tablet typically contains Clonazepam (0.5 mg) and Escitalopram Oxalate (5 mg). Clonazepam is a benzodiazepine that enhances the effect of gamma-aminobutyric acid (GABA), a chemical messenger that calms nerve activity in the brain. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels in the brain, improving mood and behavior.

Uses: Rexipra Plus Tablet is primarily prescribed for the treatment of anxiety disorders. It is also used to manage comorbid depression and anxiety disorder, generalized anxiety disorder, and panic disorder. Additionally, it may help alleviate symptoms of obsessive-compulsive disorder (OCD) and improve sleep quality by reducing anxiety and depression.

Dosage and Administration: This medicine should be taken as prescribed by a doctor, usually once daily, with or without food. It is advised to take it at the same time each day to maintain consistent medicine levels. The tablet should be swallowed whole and not crushed, chewed, or broken. Do not stop taking it abruptly, as this can lead to withdrawal symptoms.

Side Effects: Common side effects include drowsiness, dizziness, nausea, diarrhea, vomiting, memory impairment, fatigue, low sexual desire, delayed ejaculation, confusion, and uncoordinated body movements. More serious effects, such as an increase in suicidal thoughts and behaviors, especially in teenagers and young adults, have been reported; therefore, it should be used under strict medical supervision.

Precautions: Alcohol consumption should be avoided while taking Rexipra Plus Tablet, as it can increase drowsiness and other side effects. Patients should exercise caution when driving or operating heavy machinery due to potential dizziness and drowsiness. Consult a doctor if pregnant, breastfeeding, or if there is a history of liver disease, kidney disease, heart disease, epilepsy, glaucoma, or bleeding disorders. It may interact with other medications, including antidepressants, antipsychotics, antihypertensives, antibiotics, and MAO inhibitors.

Storage: Store Rexipra Plus Tablet at room temperature, away from excessive heat, direct light, and moisture. Keep it out of the sight and reach of children and pets. It should ideally be stored at temperatures between 10ºC and 25ºC or below 30ºC.

Frequently Asked Questions (FAQs) about Rexipra Plus Tablet

Rexipra Plus Tablet, manufactured by Intas Pharmaceuticals Ltd., is a prescription medicine combining two active ingredients: Escitalopram and Clonazepam. This medication is primarily used to treat various mental health conditions.

What is Rexipra Plus Tablet used for?

Rexipra Plus Tablet is prescribed for the treatment of generalized anxiety disorder, depression, panic disorder, and panic attacks. It can also be used for major depressive disorder, obsessive-compulsive disorder (OCD), and social anxiety disorder.

How does Rexipra Plus Tablet work?

Rexipra Plus Tablet contains two active components: Escitalopram and Clonazepam. Escitalopram is a Selective Serotonin Reuptake Inhibitor (SSRI) that works by increasing the levels of serotonin, a natural chemical messenger in the brain that helps regulate mood, emotions, and sleep. Clonazepam is a benzodiazepine that enhances the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that helps to calm the nervous system and reduce abnormal nerve cell activity in the brain. This dual action helps to alleviate symptoms of anxiety and depression.

What is the usual dosage of Rexipra Plus Tablet?

The dosage and duration of treatment for Rexipra Plus Tablet should be strictly followed as prescribed by your doctor. It is typically taken once a day, preferably at a fixed time each day, with or without food. Your doctor may start with a low dose and gradually increase it based on your condition and response to the medication. Do not crush, chew, or break the tablet; swallow it whole.

What are the possible side effects of Rexipra Plus Tablet?

Common side effects may include drowsiness, dizziness, confusion, memory impairment, nausea, diarrhea, tiredness, uncoordinated body movements, decreased libido (low sexual desire), and delayed ejaculation or anorgasmia. More serious, though rare, side effects can include unusual excitement, sleeplessness, or an increase in suicidal thoughts, especially in teenagers, children, and young adults. If any side effects persist or worsen, you should consult your doctor.

Is Rexipra Plus Tablet safe during pregnancy or breastfeeding?

Rexipra Plus Tablet is generally not recommended during pregnancy, particularly in the first three months, as it may pose a risk to the developing baby. It is considered unsafe to use while breastfeeding, as studies have shown it can be excreted in breast milk and may affect the infant. Always consult your doctor for advice if you are pregnant, planning to conceive, or breastfeeding.

Can Rexipra Plus Tablet be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting Rexipra Plus Tablet. This medication can interact with various drugs, including other antidepressants, antipsychotics, pain medications, sedatives, antihistamines, hypnotics, MAO inhibitors, lithium, valproic acid, and certain antibiotics. These interactions can affect how the medicine works or increase the risk of side effects.

What precautions should be taken while taking Rexipra Plus Tablet?

Avoid consuming alcohol while taking Rexipra Plus Tablet, as it can increase side effects like drowsiness and dizziness and may worsen depression. Due to the potential for drowsiness, dizziness, or confusion, avoid driving, operating heavy machinery, or engaging in activities that require high mental alertness until you know how the medicine affects you. Inform your doctor if you have a history of liver disease, kidney disease, heart problems, seizures, bipolar disorder, diabetes, narrow-angle glaucoma, or any bleeding disorders. Do not stop taking this medicine abruptly without consulting your doctor, as it can lead to withdrawal symptoms such as anxiety, mood changes, restlessness, dizziness, and sleep disturbances. Rexipra Plus has a potential for habit formation.

What happens if a dose of Rexipra Plus Tablet is missed?

If you miss a dose of Rexipra Plus Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take extra medicine to make up for a missed dose.

How should Rexipra Plus Tablet be stored?

Rexipra Plus Tablet should be stored at room temperature, ideally between 10°C to 25°C or below 30°C. Keep the medication in a tightly closed container, away from heat, direct light, and moisture. Ensure it is kept out of the reach of children and pets. Avoid storing it in the bathroom due to moisture.