Gantra 10mg Tab

GANTRA 10MG TAB by DR REDDY S LABORATORIES LTD

Gantra 10mg Tablet is a medication prescribed for adults with chronic heart failure. It works by improving the heart's pumping activity and relaxing blood vessels, thereby enhancing blood circulation throughout the body.

Name

• Brand Name: GANTRA 10MG TAB
• Common Name: Vericiguat

Composition

• Active Ingredient: Vericiguat 10mg
• Pharmacological Category: Soluble guanylate cyclase stimulator

Uses Gantra 10mg Tablet is used to manage symptomatic chronic heart failure with reduced ejection fraction (less than 45%) in adults. It helps to reduce the risk of cardiovascular death and heart failure-related hospitalizations, particularly in patients who have recently been hospitalized or required intravenous medications for heart failure. This medication also helps to alleviate symptoms such as shortness of breath and fatigue.

Dosage and Administration Take Gantra 10mg Tablet orally with food, at a fixed time each day, as prescribed by your doctor. Swallow the tablet whole with water; do not chew, crush, or break it. For patients with difficulty swallowing, the tablet may be crushed and mixed with water. The typical starting dose for adults is 2.5 mg once daily, which may be gradually increased by your doctor up to a maximum of 10 mg daily based on your response and tolerance. Do not discontinue the medication without completing the full course, even if you feel better.

Side Effects Common side effects include hypotension (low blood pressure), anemia (low red blood cell count), dizziness, headache, nausea, vomiting, indigestion, and heartburn. Most of these effects are temporary as your body adjusts to the medicine. Serious side effects, though rare, can include severe hypotension or allergic reactions.

Precautions

• Pregnancy: Gantra 10mg Tablet is contraindicated in pregnancy due to potential harm to the fetus. Women of reproductive potential must use effective contraception during treatment and for at least one month after the final dose.
• Breastfeeding: Not recommended during breastfeeding, as it is unknown if the medicine passes into breast milk and could harm the infant.
• Driving: Exercise caution when driving or operating machinery, as the medicine may cause dizziness.
• Medical Conditions: Use with caution in patients with severe liver failure, severe kidney disease (including those on dialysis), or pre-existing low blood pressure.
• Drug Interactions: Avoid concomitant use with other soluble guanylate cyclase stimulators (e.g., riociguat) or PDE5 inhibitors (e.g., sildenafil, tadalafil, vardenafil) due to the risk of severe hypotension. The use of nitrates (e.g., isosorbide mononitrate) should also be avoided.

Storage Store Gantra 10mg Tablet below 30°C, in a cool and dry place, protected from light and moisture. Keep it out of the reach and sight of children.

GANTRA 10MG TAB (Vericiguat) is a medication used to treat chronic heart failure. Here are some frequently asked questions about this medicine.

What is GANTRA 10MG TAB used for?

GANTRA 10MG TAB is used to manage adults with long-term (chronic) heart failure who have experienced a recent worsening of symptoms, such as a recent hospitalization or the need for intravenous medications. It is specifically for patients with a left ventricular ejection fraction (LVEF) of less than 45 percent, aiming to reduce the risk of cardiovascular death and hospitalizations related to heart failure.

How does GANTRA 10MG TAB work?

GANTRA 10MG TAB contains Vericiguat, a soluble guanylate cyclase (sGC) stimulator. It works by activating this enzyme in the body, which helps to relax and widen blood vessels, improving blood flow, and reducing the strain on the heart. This action makes it easier for the heart to pump blood effectively throughout the body, ultimately improving cardiac function.

What is the usual dosage of GANTRA 10MG TAB?

The usual starting dose for adults is typically 2.5 mg once daily with food. Your doctor may gradually increase the dose up to a maximum of 10 mg daily, based on your response and tolerance. It should be taken at the same time each day, swallowed whole with a glass of water, and not crushed or chewed unless advised by your doctor. If you cannot swallow the tablet, it may be crushed and mixed with water and taken immediately.

What are the possible side effects of GANTRA 10MG TAB?

The most common side effects include low blood pressure (hypotension), which can cause dizziness and lightheadedness, and anemia (low number of red blood cells), which may lead to pale skin, weakness, or breathlessness. Other reported side effects include headache, nausea, vomiting, indigestion (dyspepsia), and heartburn (gastro-oesophageal reflux disease).

Is GANTRA 10MG TAB safe during pregnancy or breastfeeding?

GANTRA 10MG TAB is not recommended for use during pregnancy as it is known to cause fetal harm. Females of reproductive potential should use effective contraception during treatment and for at least one month after the final dose.

It is also generally not recommended during breastfeeding because it is unknown if the medicine passes into breast milk and could harm the baby. Your doctor will weigh the benefits and risks to decide if breastfeeding or the medication should be stopped.

Can GANTRA 10MG TAB be taken with other medications?

You should inform your doctor about all medicines you are taking, including prescription, non-prescription, and herbal medicines. GANTRA 10MG TAB should not be taken with other soluble guanylate cyclase stimulators (e.g., riociguat) or with PDE5 inhibitors (e.g., sildenafil, tadalafil, and vardenafil) due to the risk of dangerously low blood pressure. It should also be avoided with nitrates (e.g., isosorbide mononitrate) for heart disease.

What precautions should be taken with GANTRA 10MG TAB?

Exercise caution if you have severe liver failure, severe kidney disease, are on dialysis, or have existing low blood pressure. It can cause dizziness and lightheadedness, so avoid driving or operating machinery if you experience these symptoms. Regular monitoring of blood pressure and blood tests for anemia may be required.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember on the same day. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten tablet.

How should GANTRA 10MG TAB be stored?

GANTRA 10MG TAB should be kept out of reach and sight of children. It should be stored in a cool and dry place, below 25°C or 30°C, away from direct sunlight and moisture.