Pantin D Capsule (10 Cap)

PANTIN D CAPSULE (10 CAP) by HETERO HEALTHCARE LIMITED

Pantin D Capsule is a combination medicine primarily used to manage gastroesophageal reflux disease (GERD) and other gastrointestinal disorders. It combines a proton pump inhibitor and a dopamine antagonist to address both acid production and gastric motility issues.

• Name:
  • Brand Name: Pantin D Capsule
• Composition:
  • Pantin D Capsule contains two active ingredients: Domperidone (30 mg) and Pantoprazole (40 mg).
  • Pantoprazole is a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach.
  • Domperidone is a dopamine antagonist with antiemetic and prokinetic properties, which helps to increase the movement of food through the stomach and intestines and to control nausea and vomiting.
• Uses:
  • Management of Gastroesophageal Reflux Disease (GERD), including acid reflux and heartburn.
  • Treatment of erosive esophagitis (inflammation of the esophagus due to acid reflux).
  • Control of Zollinger-Ellison syndrome and other conditions involving excessive acid secretion.
  • Relief from nausea and vomiting associated with gastroparesis, reflux disease, or migraines.
  • Healing of gastric and duodenal ulcers.
  • Alleviates symptoms of indigestion (dyspepsia), gastritis, stomach pain, bloating, and upper abdominal discomfort.
• Dosage and Administration:
  • Pantin D Capsule should be taken as directed by a doctor.
  • Typically, one capsule is taken once daily, preferably in the morning, 30-60 minutes before a meal, on an empty stomach.
  • Swallow the capsule whole with a glass of water; do not crush, chew, or open it.
  • The duration of treatment is usually short-term, typically up to 4-8 weeks, to allow the esophagus to heal, but follow your doctor's advice.
• Side Effects:
  • Common Side Effects: Headache, diarrhea, abdominal pain, nausea, vomiting, dizziness, fatigue, rash, dry mouth, flatulence (gas), and constipation.
  • Rare/Serious Side Effects: Gynecomastia (breast enlargement in men) and galactorrhea (milk production in women not breastfeeding), severe allergic reactions, severe dizziness or fainting, persistent stomach pain, or unusual bleeding.
• Precautions:
  • Allergy: Avoid if allergic to domperidone, pantoprazole, or any other ingredients.
  • Pregnancy and Breastfeeding: Caution is advised. Consult a doctor as it may be excreted in breast milk and should only be used if benefits outweigh risks.
  • Alcohol: It is advisable to avoid alcohol as it may worsen side effects like dizziness and sleepiness.
  • Liver/Kidney Disease: Use with caution in patients with kidney or liver problems. Dose reduction may be needed in moderate to severe liver impairment.
  • Heart Disease: Domperidone can prolong the QT interval, especially at higher doses or in patients with pre-existing heart disease. ECG monitoring may be recommended.
  • Bone Disorders: Long-term use of pantoprazole may increase the risk of fractures and can lead to deficiencies in Vitamin B12 and magnesium. Regular monitoring may be advised.
  • Driving/Operating Machinery: May cause dizziness and sleepiness, so avoid these activities until you know how the medicine affects you.
  • Drug Interactions: Inform your doctor about all other medications, especially CYP3A4 inhibitors (e.g., itraconazole, erythromycin), acid-dependent medicines (e.g., ketoconazole, digoxin), and blood-thinning medications (e.g., warfarin).
  • Children: Not recommended for children below 12 years.
• Storage:
  • Store in a cool, dry place at room temperature, ideally below 30°C.
  • Protect from light and moisture.
  • Keep out of reach of children.

What is Pantin D Capsule used for?

Pantin D Capsule is primarily used to manage gastroesophageal reflux disease (GERD), which is also known as acid reflux. It helps alleviate symptoms such as heartburn, indigestion, chest pain, discomfort, and irritation associated with acid reflux. The medicine is also effective in treating peptic ulcers, erosive esophagitis (inflammation of the food pipe), Zollinger-Ellison syndrome, and other conditions that cause excessive acid secretion in the stomach. Additionally, it can reduce nausea and vomiting linked to gastroparesis or migraines.

How does Pantin D Capsule work?

Pantin D Capsule is a combination medicine containing two active ingredients: Pantoprazole and Domperidone. Pantoprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach. Domperidone is a prokinetic agent and dopamine antagonist that improves the movement of food through the stomach and intestines, helping to prevent acid backflow into the food pipe and controlling feelings of nausea and vomiting.

What is the usual dosage for Pantin D Capsule?

The usual dosage for Pantin D Capsule is typically once daily, preferably in the morning. It should be taken 30-60 minutes before a meal with a glass of water. The capsule should be swallowed whole and not crushed, chewed, or opened. Your doctor will determine the exact dose, duration, and frequency based on your health condition and response to treatment.

What are the possible side effects of Pantin D Capsule?

Common side effects of Pantin D Capsule may include headache, diarrhea, abdominal pain, nausea, vomiting, dizziness, fatigue, rash, and dry mouth. Most of these side effects are usually temporary and resolve on their own. Rarely, more serious side effects like breast enlargement in men (gynecomastia) or milk production in women when not breastfeeding (galactorrhea) can occur. If you experience any persistent or severe side effects, it is important to consult your doctor.

Is Pantin D Capsule safe during pregnancy or breastfeeding?

Caution is advised when taking Pantin D Capsule during pregnancy. It is generally not considered safe and should only be used if your doctor determines the benefits outweigh the potential risks to the unborn child, and often under strict medical supervision. Pantin D Capsule is excreted in breast milk, so it should be used with caution during breastfeeding. Consult your doctor before using this medicine if you are pregnant or breastfeeding.

Can Pantin D Capsule be taken with other medications?

Pantin D Capsule can interact with certain medications. It may affect the absorption of medicines that require an acidic stomach for proper absorption, such as ketoconazole and digoxin. Other potential interactions include CYP3A4 inhibitors (e.g., itraconazole, erythromycin), blood-thinning medications like warfarin, atazanavir, nelfinavir, iron supplements, ampicillin, and methotrexate. It is generally recommended to avoid taking antacids within two hours of Pantin D Capsule as it may affect its absorption. Always inform your doctor about all other medications, supplements, and herbal products you are taking to prevent potential drug interactions.

What precautions should be taken while using Pantin D Capsule?

You should avoid consuming alcohol while taking Pantin D Capsule, as it can worsen side effects and may increase stomach acidity. Exercise caution if you have kidney or liver disease, heart conditions (domperidone can prolong the QT interval), or bone disorders, as long-term use of pantoprazole may increase the risk of fractures and deficiencies in Vitamin B12 and magnesium. Pantin D Capsule might cause dizziness or sleepiness, so avoid driving or operating heavy machinery until you know how the medicine affects you. It is contraindicated in patients with C. difficile-induced colitis or lupus erythematosus.

What happens if a dose of Pantin D Capsule is missed?

If you miss a dose of Pantin D Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Pantin D Capsule be stored?

Pantin D Capsule should be stored in a cool, dry place at room temperature, ideally below 30°C or between 10ºC to 25ºC. Protect it from light and moisture to maintain its efficacy. Always keep this medicine out of the sight and reach of children and pets.