Dapacose S 10/100mg Tab

DAPACOSE S 10/100MG TAB by J.B.CHEMICALS

• Name: DAPACOSE S 10/100MG TAB

• Composition: Dapacose S 10/100mg Tablet contains a combination of Dapagliflozin (10 mg) and Sitagliptin (100 mg) as active ingredients.

• Uses: This medication is primarily used for the management of type 2 diabetes mellitus in adults. It is prescribed when blood sugar levels are not adequately controlled by diet and exercise alone, or by metformin alone. Dapacose S helps to improve blood sugar control, reduce the risk of serious diabetes complications such as kidney damage, blindness, nerve problems, and may also lessen the risk of heart attack, heart failure, or other cardiovascular events. It is also used to treat chronic kidney disease in adults with reduced kidney function.

• Dosage and Administration: Dapacose S 10/100mg Tablet should be taken orally, typically once daily. It can be taken with or without food, but it is recommended to take it at the same time each day for optimal benefits. The tablet should be swallowed whole with a glass of water and not crushed or chewed. Dosage is determined by a healthcare professional, and patients should not stop taking the medicine without consulting their doctor.

• Side Effects:

  • Common: Urinary tract infections, nasal congestion, sore throat, upper respiratory tract infections, headache, dizziness, rashes, painful urination, fungal infections in the genital area, diarrhea, and nausea. Low blood sugar (hypoglycemia) can occur, especially when used with insulin or sulphonylureas.
  • Serious: Pancreatitis (severe abdominal pain), dehydration, low blood pressure, severe allergic reactions (e.g., swelling of the face, tongue, lips), diabetic ketoacidosis, and Fournier's gangrene (a serious genital or perineal infection).

• Precautions:

  • Contraindications: Do not use if allergic to dapagliflozin, sitagliptin, or any other ingredients. It is also contraindicated in patients with type 1 diabetes mellitus, diabetic ketoacidosis, or severe kidney or liver disease.
  • Warnings: Inform your doctor if you have kidney or liver issues, urinary tract infections, heart failure, or are taking diuretics. Caution is advised in elderly patients (≥ 65 years) or those with a history of low blood pressure. Excessive alcohol consumption should be avoided as it can interfere with blood sugar levels and increase side effects.
  • Pregnancy and Breastfeeding: Dapacose S is contraindicated during the second and third trimesters of pregnancy and is not advised for use in breastfeeding women.
  • Drug Interactions: Exercise caution when taken with diuretics, insulin, insulin secretagogues (e.g., sulphonylureas) as these can increase the risk of dehydration, low blood pressure, or hypoglycemia.

• Storage: Store Dapacose S Tablet in a cool and dry place, below 30°C, away from the reach of children. Do not use the medication past its expiration date.

Here are some frequently asked questions about DAPACOSE S 10/100MG TAB:

What is DAPACOSE S 10/100MG TAB used for?

DAPACOSE S 10/100MG TAB is primarily used to manage Type 2 diabetes mellitus in adults. It helps control blood sugar levels when diet and exercise alone, or other medications like metformin, are not sufficient. This medication can also reduce the risk of cardiovascular events like heart attack and heart failure, and it is used to treat chronic kidney disease in adults with reduced kidney function.

How does DAPACOSE S 10/100MG TAB work?

This medicine combines two active ingredients: Dapagliflozin (10 mg) and Sitagliptin (100 mg). Dapagliflozin, an SGLT2 inhibitor, works by preventing the kidneys from reabsorbing glucose, leading to increased glucose excretion in the urine and thus lowering blood sugar levels. Sitagliptin, a DPP-4 inhibitor, increases the levels of natural substances called incretins, which stimulate the pancreas to produce more insulin after meals and reduce the amount of glucose produced by the liver.

What is the usual dosage for DAPACOSE S 10/100MG TAB?

DAPACOSE S 10/100MG TAB is typically taken once daily, with or without food. For optimal benefits, it's recommended to take it at the same time each day. Your doctor will determine the appropriate dosage based on your medical condition and response to treatment.

What are the possible side effects of DAPACOSE S 10/100MG TAB?

Common side effects include urinary tract infections, nasal congestion, sore throat, upper respiratory tract infections, and fungal infections in the genital area. Other possible side effects include headache, back pain, joint pain, diarrhea, nausea, and hypoglycemia (low blood sugar), especially when taken with other anti-diabetic medicines.

Is DAPACOSE S 10/100MG TAB safe during pregnancy or breastfeeding?

DAPACOSE S 10/100MG TAB is generally not recommended during pregnancy, especially in the second and third trimesters, as there is limited information on its effects on pregnant women and potential risks to the developing baby. It is also not advised during breastfeeding, as the medication may pass into breast milk and potentially cause adverse effects in infants. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can DAPACOSE S 10/100MG TAB be taken with other medications?

You should inform your doctor about all other medicines, herbal products, or supplements you are currently taking or plan to take to avoid potential drug interactions. Caution is advised when taking this medicine with diuretics (water pills) like furosemide, as it may increase the risk of dehydration and low blood pressure. Concurrent use with insulin or insulin secretagogues (like sulfonylureas) may also increase the risk of low blood sugar.

What precautions should be taken while on DAPACOSE S 10/100MG TAB?

It is important to drink plenty of fluids to prevent dehydration, as this medication can increase urination. Maintaining good personal hygiene is recommended to help prevent genital fungal infections. Inform your doctor if you have kidney or liver issues, a history of urinary tract infections, or if you are scheduled for surgery. Also, limit alcohol consumption as it can affect blood sugar levels. Regular monitoring of blood sugar levels is crucial.

What happens if a dose of DAPACOSE S 10/100MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Do not stop taking the medication without consulting your doctor.

How should DAPACOSE S 10/100MG TAB be stored?

Store DAPACOSE S 10/100MG TAB in a cool, dry place, away from direct sunlight. Keep the medicine out of the reach of children. Do not use the medication past its expiry date.