Piclin Syrup

PICLIN SYRUP by LUPIN LTD

Piclin Syrup, manufactured by Lupin Ltd., is a stimulant laxative used to treat constipation. It is primarily prescribed for managing occasional or short-term constipation by promoting bowel movements and softening stools.

Composition The active ingredient in Piclin Syrup is Sodium Picosulfate, typically 5 mg per 5 ml.

Uses Piclin Syrup is prescribed for the relief of constipation, including that associated with conditions like piles, anal fissures, hernia, and cardiovascular disorders. It is also used for bowel clearance before medical procedures such as endoscopy or radioscopy, especially in elderly or bedridden patients.

Dosage and Administration This medicine is generally taken once daily at bedtime, as its effects usually begin within 6-12 hours. It can be taken with or without food. For adults, the typical dose is 5-10 mg daily at bedtime. For children aged 9 years and older, dosage should be as advised by a healthcare professional, with general guidelines of 5-10 mg for those over 10 years, and 2.5-5 mg for ages 4-10 years. It is important not to use Piclin Syrup for more than 5 to 7 consecutive days to avoid dependency and electrolyte imbalance. Maintaining adequate fluid intake (6-8 glasses of water daily) is crucial during treatment to prevent dehydration. If other medications are being taken, Piclin Syrup should be administered about 2 hours later to prevent interference with absorption.

Side Effects Common side effects may include abdominal pain, cramps, discomfort, diarrhea, nausea, vomiting, and headache. Prolonged or excessive use can lead to serious side effects such as dehydration, electrolyte imbalance, and in rare cases, dizziness or fainting (syncope).

Precautions Piclin Syrup should not be used if you have an allergy to its ingredients, severe dehydration, intestinal obstruction, acute inflammatory bowel disease, appendicitis, or severe abdominal pain with vomiting and nausea. Consult a doctor if you are pregnant or breastfeeding, or if you have pre-existing conditions like heart issues, inflammatory bowel disease, or low blood sodium levels. It may interact with certain medications, including antibiotics, diuretics, steroids, and anticonvulsants, potentially affecting their absorption or increasing the risk of electrolyte imbalance. Alcohol consumption during treatment is not well-studied, so caution is advised.

Storage Store Piclin Syrup in a cool, dry place, away from direct sunlight, at a temperature below 30°C, and out of the reach of children.

What is Piclin Syrup used for?

Piclin Syrup is a laxative primarily used for the short-term relief of constipation. It can also be used for bowel cleansing before diagnostic procedures like colonoscopy, endoscopy, or radiological investigations, and before surgical procedures, especially in elderly or bed-ridden patients, or those with conditions like hemorrhoids, anal fissures, or hernia.

How does Piclin Syrup work?

Piclin Syrup contains Sodium Picosulfate, which is a stimulant laxative. It works by preventing the absorption of water in the colon and intestine, thereby stimulating the muscles in the bowel to move waste products through the body. This process promotes the accumulation of water, which softens the stool and makes it easier to pass.

What is the usual dosage for Piclin Syrup?

For adults and children over 12 years, the typical dose is 5-10 ml (or one to two 5 ml spoonfuls) taken once daily, usually at bedtime. It's recommended to take it at night because it generally takes about 6-12 hours to produce a bowel movement. For children under 10-12 years, use only as advised by a doctor, with specific dosing for very young children.

What are the possible side effects of Piclin Syrup?

Common side effects include diarrhea, abdominal discomfort, pain, cramps, nausea, headache, and dizziness. Serious side effects, which require immediate medical attention, include allergic reactions (skin rash, itching, hives, swelling), severe dehydration (increased thirst, dry mouth, feeling faint or lightheaded, dark urine), fast or irregular heartbeat, kidney injury, and seizures.

Is Piclin Syrup safe during pregnancy or breastfeeding?

• Pregnancy: If you are pregnant or planning to become pregnant, consult your doctor before taking Piclin Syrup. Your doctor will determine if the benefits outweigh the potential risks.
• Breastfeeding: Sodium picosulfate, the active ingredient, is considered compatible with breastfeeding. It is not significantly absorbed from the gastrointestinal tract, and its active metabolite is not detectable in breast milk, so no special precautions are generally required.

Can Piclin Syrup be taken with other medications?

Piclin Syrup can interact with other medications. It is generally advised to take other oral medications at least 1 hour before or 6 hours after taking Piclin Syrup to prevent interference with their absorption. Specifically, certain antibiotics may reduce the efficacy of Sodium Picosulfate. There is an increased risk of electrolyte imbalance when taken with diuretics or corticosteroids. Medications such as digoxin, chlorpromazine, fluoroquinolone antibiotics, iron supplements, penicillamine, and tetracycline may require specific timing (2 hours before, 6 hours after Piclin Syrup). Do not take other laxatives concurrently.

What precautions should be taken while using Piclin Syrup?

Do not use Piclin Syrup for more than 5 to 7 days without consulting your doctor to avoid dependency and dehydration. It is crucial to stay well-hydrated by drinking plenty of clear fluids while taking this medication. Since it can cause dizziness, avoid driving or operating machinery until you know how it affects you. Inform your doctor about any pre-existing conditions such as dehydration, heart disease, kidney disease, electrolyte imbalances, inflammatory bowel disease, or intestinal obstruction.

What happens if a dose of Piclin Syrup is missed?

If you miss a dose, do not take a double dose to make up for the missed one. Simply skip the missed dose and continue with your regular dosing schedule.

How should Piclin Syrup be stored?

Store Piclin Syrup at room temperature, typically between 20 and 25 degrees Celsius (68 and 77 degrees Fahrenheit), or below 30 degrees Celsius. Keep it in a closed container, away from heat, moisture, and direct light. Do not refrigerate or freeze the syrup. Ensure it is kept out of the sight and reach of children.