Amantrel Er 129mg Tab

AMANTREL ER 129MG TAB by CIPLA LTD is an extended-release medication primarily used in the management of Parkinson's disease and certain viral infections.

• Name: AMANTREL ER 129MG TAB (Brand name). The common name for the active ingredient is Amantadine.
• Composition: Each tablet contains Amantadine 129mg in an extended-release formulation. Amantadine acts as a dopamine agonist.
• Uses:
  • Parkinson's Disease: It is prescribed alone or with other medications to alleviate symptoms of Parkinson's disease, such as tremors, muscle stiffness, impaired posture, balance issues, and slow movements. It functions by increasing dopamine levels in the brain, essential for movement control.
  • Drug-Induced Movement Disorders: It can also treat extrapyramidal reactions caused by certain medications.
  • Influenza A: AMANTREL ER can be used for the prevention and treatment of influenza A viral infections due to its antiviral properties.
  • Shingles: It may be used to manage pain associated with shingles (herpes zoster).
• Dosage and Administration:
  • Take as prescribed by your doctor.
  • The tablet can be taken with or without food, preferably at the same time daily to maintain consistent medicine levels.
  • Swallow the tablet whole; do not chew, crush, or break it.
  • If a dose is missed, take it as soon as remembered, but skip it if it's almost time for the next dose.
  • Do not stop taking this medication abruptly without consulting your doctor, as sudden discontinuation can worsen Parkinsonism or lead to withdrawal symptoms.
• Side Effects:
  • Common: Nausea, dizziness, insomnia (difficulty sleeping), dry mouth, constipation, blurred vision, hallucinations, peripheral edema (swelling in the extremities), balance disorder, headache, sweating, loss of appetite, anxiety, tiredness, difficulty concentrating, nervousness, nightmares, and muscle pain.
  • Serious: May increase the risk of seizures and impulse control disorders (e.g., gambling, increased sexual urges). Orthostatic hypotension (dizziness or fainting upon standing) can also occur.
• Precautions:
  • Use with caution in patients with kidney or liver disease, heart conditions, mental illnesses (e.g., schizophrenia, dementia), and glaucoma.
  • It is contraindicated in patients with severe renal impairment, epilepsy, stomach/intestinal ulcers, and known allergy to amantadine.
  • Avoid alcohol consumption as it can increase side effects.
  • Do not drive or operate heavy machinery if experiencing dizziness, blurred vision, or confusion.
  • Not recommended during pregnancy or breastfeeding.
• Storage: Store in a cool, dry place away from direct sunlight and out of the reach of children.

Here are frequently asked questions (FAQs) about AMANTREL ER 129MG TABLET:

What is AMANTREL ER 129MG TABLET used for?

AMANTREL ER 129MG TABLET is primarily used to treat symptoms of Parkinson's disease, such as tremors, stiffness, and difficulty walking, by improving movement and coordination. It is also used for drug-induced movement disorders and can help prevent and treat influenza A viral infections.

How does AMANTREL ER 129MG TABLET work?

This medication works by increasing the levels of dopamine, a crucial neurotransmitter in the brain that controls movement, coordination, and balance. For influenza A, it acts as an antiviral agent by blocking the M2 protein, which is essential for virus replication and spread, thus preventing the virus from multiplying.

What is the usual dosage for AMANTREL ER 129MG TABLET?

The initial dosage for extended-release tablets like AMANTREL ER 129MG TABLET is typically 129 mg orally once daily in the morning. Your doctor may gradually increase the dose at weekly intervals, but it should not exceed 322 mg per day. Always follow your doctor's specific instructions.

What are the possible side effects of AMANTREL ER 129MG TABLET?

Common side effects can include nausea, dry mouth, constipation, blurred vision, difficulty sleeping (insomnia), dizziness, hallucinations, swelling in the extremities (peripheral edema), and balance disorder. Some individuals may experience dizziness or a drop in blood pressure when standing up, and rarely, compulsive behaviors or seizures. If side effects persist or worsen, consult your doctor.

Is AMANTREL ER 129MG TABLET safe during pregnancy or breastfeeding?

AMANTREL ER 129MG TABLET is generally not recommended during pregnancy, as it may pass into the baby's blood and potentially affect the developing baby. It is contraindicated during breastfeeding as it can pass into breast milk and harm the baby. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can AMANTREL ER 129MG TABLET be taken with other medications?

AMANTREL ER 129MG TABLET can interact with several medications. Concomitant use with other anti-Parkinsonian agents (like procyclidine, orphenadrine, levodopa) or antipsychotic agents (like chlorpromazine, haloperidol) can increase side effects. Diuretics (water pills) may decrease its effect. It should also not be taken with live attenuated influenza vaccine within 2 weeks before or 48 hours after vaccination. Always inform your doctor about all medicines, supplements, or herbal products you are taking.

What precautions should be taken while using AMANTREL ER 129MG TABLET?

Exercise caution if you have kidney or liver disease, heart conditions (such as heart failure, low blood pressure), mental illness, glaucoma, epilepsy, sleep disorders, or skin conditions like eczema. Avoid alcohol consumption, and do not drive or operate heavy machinery until you understand how the medication affects you, as it can cause dizziness or confusion. Do not stop taking the medicine abruptly, as it can worsen Parkinsonian symptoms and lead to withdrawal symptoms.

What happens if a dose of AMANTREL ER 129MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should AMANTREL ER 129MG TABLET be stored?

Store AMANTREL ER 129MG TABLET in a cool and dry place, typically below 30°C. Keep it in its original packaging, away from direct sunlight, and out of sight and reach of children.