Tizan 2 Mg Tablet (10 Tab)

TIZAN 2 MG TABLET

Tizan 2 MG Tablet is a skeletal muscle relaxant used to manage muscle spasticity and discomfort associated with acute, painful musculoskeletal conditions. It is manufactured by Sun Pharma Laboratories Ltd.

• Name:

  • Brand Name: Tizan 2 MG Tablet
  • Common Name (Active Ingredient): Tizanidine

• Composition:

  • Each tablet contains Tizanidine 2 mg.

• Uses: Tizan 2 MG Tablet is prescribed for:

  • Relieving muscle stiffness, tension, rigidity, and spasms in acute, painful musculoskeletal conditions.
  • Managing muscle spasticity (when muscles become heavy, stiff, and difficult to move) caused by conditions such as multiple sclerosis, spinal cord injury, or other diseases of the spinal cord.

• Dosage and Administration:

  • The recommended starting dose for adults is typically 2 mg every 6 to 8 hours as needed.
  • It can be taken with or without food, but it is important to maintain consistency in how it is taken each time (either always with food or always without food).
  • Swallow the tablet whole; do not chew, crush, or break it.
  • Dosage can be gradually increased by 2 mg to 4 mg per dose, with 1 to 4 days between increases, until a satisfactory reduction in muscle tone is achieved.
  • The maximum single dose should not exceed 16 mg, and the total daily dose should not exceed 36 mg in 24 hours (up to a maximum of three doses in 24 hours).
  • If discontinuing therapy, the dose should be decreased slowly (2 mg to 4 mg per day) to minimize the risk of withdrawal symptoms.

• Side Effects:

  • Common Side Effects: Dry mouth, sleepiness/drowsiness, tiredness/fatigue, dizziness, constipation, nervousness, flu-like symptoms, vomiting, increased frequency of urination, sore throat, runny nose, blurred vision, weakness, headache, and stomach upset.
  • Serious Side Effects (seek immediate medical attention): Nausea, extreme tiredness, lack of energy, loss of appetite, unusual bleeding or bruising, pain in the upper right part of the stomach, yellowing of the skin or eyes (indicating liver damage), rash, hives, itching, swelling of the face, throat, tongue, lips, or eyes, shortness of breath, difficulty breathing or swallowing, seeing things or hearing voices that do not exist (hallucinations), slow heartbeat, changes in vision, and low blood pressure.

• Precautions:

  • Avoid consuming alcohol while taking Tizan 2 MG Tablet, as it may cause excessive drowsiness and increase the risk of adverse effects.
  • Tizan 2 MG Tablet may cause dizziness, drowsiness, or blurred vision. Patients should avoid driving or operating machinery until they know how the medicine affects them.
  • Concomitant use with fluvoxamine or ciprofloxacin is contraindicated, as it can lead to serious adverse effects such as decreased blood pressure, excessive sleepiness, slurred speech, dizziness, weakness, and confusion.
  • Caution is advised in patients with kidney or liver disease; dose adjustments may be necessary.
  • Use with caution in patients with low blood pressure.
  • Pregnant or breastfeeding women should consult a doctor before using this medication, as it is generally not recommended unless absolutely necessary.
  • Inform your doctor about all other medicines and herbal preparations you are taking to avoid potential drug interactions.
  • Do not stop taking this medicine suddenly without consulting your doctor, as abrupt discontinuation can lead to withdrawal symptoms such as rebound hypertension, tachycardia, and hypertonia.
  • Women taking oral contraceptives should use Tizan 2 MG Tablet with caution, as clearance of tizanidine is reduced by approximately 50%, potentially requiring individual dose reductions during titration.
  • Do not exceed more than 3 doses of Tizan 2 MG Tablet in a single day, or a total daily dose of 36 mg, to prevent potential liver damage.

• Storage:

  • Store Tizan 2 MG Tablet at room temperature in a cool and dry place, below 30°C.
  • Keep it out of the reach of children and pets.

TIZAN 2 MG TABLET contains Tizanidine, a muscle relaxant primarily used to alleviate muscle spasticity and discomfort associated with acute, painful musculoskeletal conditions. Below are some frequently asked questions regarding this medication.

What is Tizan 2 mg Tablet used for?

Tizan 2 mg Tablet is a skeletal muscle relaxant used to treat muscle spasticity, a condition where muscles become stiff, heavy, and difficult to move. It helps relieve discomfort from acute, painful musculoskeletal conditions such as stiffness, tension, rigidity, and muscle spasms. It can also be used to manage muscle stiffness and restriction caused by conditions like multiple sclerosis, spinal cord injury, or other diseases of the spinal cord.

How does Tizan 2 mg Tablet work?

Tizan 2 mg Tablet works by acting on the centers of the spinal cord and brain. Its active ingredient, Tizanidine, is an agonist at alpha-2 adrenergic receptor sites. This action reduces the release of excitatory neurotransmitters like glutamate and aspartate from spinal interneurons, which are responsible for muscle tightness and spasms. By doing so, it helps relax muscles, relieve stiffness, and improve muscle movements without reducing muscle strength.

What is the usual dosage for Tizan 2 mg Tablet?

The recommended starting dose for Tizan 2 mg Tablet is 2 milligrams (mg) every 6 to 8 hours, as needed, up to a maximum of three doses in 24 hours. Your doctor may gradually adjust the dose by 2 mg to 4 mg at each dose, with 1 to 4 days between increases, until a satisfactory reduction of muscle tone is achieved. The total daily dose should not exceed 36 mg. It's crucial to follow your doctor's prescribed dosage and not to exceed the maximum daily limit, as too much Tizanidine can cause liver damage.

What are the possible side effects of Tizan 2 mg Tablet?

Common side effects of Tizan 2 mg Tablet include drowsiness, dizziness, dry mouth, tiredness, constipation, vomiting, nervousness, sore throat, runny nose, and blurred vision. Most of these side effects are mild and usually resolve over time. More serious, but less common, side effects that should be reported to your doctor immediately include signs of liver injury (e.g., right upper belly pain, loss of appetite, yellowing skin or eyes), severe allergic reactions (e.g., rash, hives, swelling of the face/throat, difficulty breathing), low blood pressure (e.g., feeling faint, lightheaded), and hallucinations.

Is Tizan 2 mg Tablet safe during pregnancy or breastfeeding?

Tizan 2 mg Tablet should generally be avoided during pregnancy as components of the medicine are known to be harmful to fetuses. If you are pregnant or plan to become pregnant, it is crucial to consult your doctor to assess the benefits and risks. Regarding breastfeeding, there is limited information, but Tizan 2 mg Tablet is likely unsafe as it may pass into breast milk and harm the baby. Therefore, it is generally not advised for use while breastfeeding; consult your doctor to discuss the risks and benefits.

Can Tizan 2 mg Tablet be taken with other medications?

Tizan 2 mg Tablet should not be taken with certain medications due to potential serious interactions. It is contraindicated with fluvoxamine (an antidepressant) and ciprofloxacin (an antibiotic) as this combination can cause significant adverse effects such as slurred speech, dizziness, weakness, confusion, drowsiness, and low blood pressure. Caution is also advised with other medications that can cause sleepiness, lower blood pressure, or affect liver function. These include other muscle relaxants, sedatives, tranquilizers, certain blood pressure medications, and some oral contraceptives. Always inform your doctor about all other medicines, herbal preparations, and supplements you are taking to avoid potential drug interactions.

What precautions should be taken while using Tizan 2 mg Tablet?

Several precautions should be taken:

• Alcohol: Avoid consuming alcohol with Tizan 2 mg Tablet, as it can increase the risk of adverse effects like excessive drowsiness and calmness.
• Driving and Machinery: This medicine may cause drowsiness, dizziness, or vision problems. Do not drive or operate machinery until you know how it affects you.
• Pre-existing Conditions: Inform your doctor if you have low blood pressure, liver, or kidney diseases, as the dose may need adjustment, and the medicine should be used with caution.
• Sudden Discontinuation: Do not stop taking Tizan 2 mg Tablet suddenly, especially if you have been on it for a long time or at high doses. Your doctor may advise a gradual reduction to prevent withdrawal symptoms like rebound hypertension, tachycardia, and increased muscle tone.
• Consistency with Food: Tizanidine's absorption can be affected by food. Always take it consistently, either always with food or always without, as advised by your doctor, to maintain consistent effects.

What happens if a dose of Tizan 2 mg Tablet is missed?

If you miss a dose of Tizan 2 mg Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of side effects.

How should Tizan 2 mg Tablet be stored?

Tizan 2 mg Tablet should be stored at room temperature in a cool and dry place. Keep it out of reach and sight of children and pets. Store in the original container and protect from heat.