Insugen 30/70 Inj 100 Iu 10 Ml (vial)

INSUGEN 30/70 INJ 100 IU 10 ML (VIAL) by BIOCON BIOLOGICS LIMITED

INSUGEN 30/70 is a premixed human insulin formulation designed for effective blood sugar management in individuals with diabetes mellitus.

• Name

  • Brand Name: INSUGEN 30/70
  • Common Name: Biphasic Isophane Insulin Injection IP

• Composition Each mL contains 100 IU of human insulin, consisting of 30% soluble human insulin (rapid-acting) and 70% isophane human insulin (intermediate-acting).

• Uses INSUGEN 30/70 is prescribed for the treatment of diabetes mellitus, including both Type 1 and Type 2 diabetes, in adults and children. It helps improve glycemic control by regulating blood sugar levels and preventing complications of diabetes.

• Dosage and Administration This medication is administered via subcutaneous injection, typically into the abdominal wall, thigh, gluteal region, or deltoid region. It is generally injected 15-30 minutes before a meal. Dosage is highly individualized and determined by a healthcare professional based on blood glucose levels, metabolic needs, diet, and physical activity. It is crucial to follow the prescribed regimen and monitor blood glucose regularly.

• Side Effects

  • Common: Hypoglycemia (low blood sugar), injection site reactions (redness, swelling, itching, pain), weight gain.
  • Less Common/Serious: Lipodystrophy (thickening or thinning of skin at injection site), allergic reactions (rash, itching, difficulty breathing), edema (swelling), diabetic retinopathy, painful neuropathy.

• Precautions Do not self-adjust dosage, and closely monitor blood sugar levels to prevent hypoglycemia or hyperglycemia. Caution is advised for patients with kidney or liver problems, as dosage adjustments may be necessary. Insulin can be used during pregnancy and lactation, but consultation with a doctor is essential for dosage adjustments. Alcohol consumption may affect blood glucose levels. Avoid injecting intravenously.

• Storage Unopened vials of INSUGEN 30/70 should be stored in the refrigerator between 2°C to 8°C (36°F to 46°F). Do not freeze. Once opened, the vial can be stored at room temperature (below 30°C) for up to 28 days. Discard any unused portion after 28 days.

Here are some frequently asked questions about INSUGEN 30/70 INJ 100 IU 10 ML (VIAL) by BIOCON BIOLOGICS LIMITED, along with their concise answers:

1. What is INSUGEN 30/70 used for?

INSUGEN 30/70 is a medication prescribed for the treatment of diabetes mellitus, including both Type 1 and Type 2 diabetes, in adults and children. It helps to regulate and improve blood sugar levels. This medication can also be used for gestational diabetes under a doctor's guidance.

2. How does INSUGEN 30/70 work?

INSUGEN 30/70 is a premixed insulin formulation containing 30% short-acting (soluble human insulin) and 70% intermediate-acting (isophane human insulin) components. The short-acting insulin helps to manage blood sugar spikes after meals, while the intermediate-acting insulin provides a longer-lasting effect to control basal blood sugar levels throughout the day. It works by facilitating the uptake of sugar into muscle and fat cells and by inhibiting the liver's production of excessive sugar.

3. What is the usual dosage for INSUGEN 30/70?

The dosage of INSUGEN 30/70 is highly individualized and determined by your doctor based on your specific needs, blood sugar levels, diet, and activity. It is typically administered subcutaneously (under the skin) 15-30 minutes before a meal, or within 20 minutes after starting a meal. It is crucial to consume a meal containing carbohydrates within 30 minutes after the injection to prevent low blood sugar. Never self-adjust your dosage.

4. What are the possible side effects of INSUGEN 30/70?

The most common side effect is hypoglycemia (low blood glucose), which can manifest as sweating, shakiness, dizziness, or confusion. Other possible side effects include reactions at the injection site such as pain, swelling, redness, or itching. Some individuals may also experience weight gain, thickening or pitting of the skin at the injection site (lipodystrophy), swelling (edema), or, rarely, allergic reactions or a temporary worsening of diabetic retinopathy.

5. Is INSUGEN 30/70 safe during pregnancy or breastfeeding?

INSUGEN 30/70 is generally considered safe for use during pregnancy and breastfeeding if prescribed by your doctor. However, close monitoring of blood sugar levels is essential, as insulin requirements may change during these periods, and dosage adjustments may be necessary.

6. Can INSUGEN 30/70 be taken with other medications?

You should inform your doctor about all medications you are taking, including prescription, over-the-counter, and herbal products, as some drugs can interact with insulin. Certain medications, such as oral hypoglycemic agents, beta-blockers, and some ACE inhibitors, may reduce insulin requirements, while others like oral contraceptives, thyroid hormones, and glucocorticoids may increase them. Concomitant use of pioglitazone with insulin has been associated with reported cases of heart failure, especially in high-risk patients.

7. What precautions should be taken when using INSUGEN 30/70?

Always inject INSUGEN 30/70 subcutaneously; it should never be administered intravenously. To prevent skin changes like thickening or pitting, it is important to rotate injection sites regularly (e.g., abdomen, thighs, buttocks, upper arm). Monitor your blood sugar levels diligently and maintain a consistent meal schedule. Avoid excessive alcohol consumption, as it can significantly lower your blood sugar. Inform your healthcare provider if you have a history of kidney, liver, or heart problems before starting this treatment. Always carry a fast-acting source of sugar, like glucose tablets or juice, to treat hypoglycemia.

8. What happens if a dose of INSUGEN 30/70 is missed?

Missing a dose can lead to hyperglycemia (high blood sugar). If you realize you missed a dose, check your blood sugar level. If it's close to your next scheduled mealtime, it's generally recommended to skip the missed dose and resume your regular schedule. Do not take a double dose to compensate, as this can cause a dangerous drop in blood sugar. Always consult your doctor or diabetes educator if you are unsure what to do after a missed dose.

9. How should INSUGEN 30/70 be stored?

Unopened vials of INSUGEN 30/70 should be stored in a refrigerator at a temperature between 2°C and 8°C (36°F to 46°F). Do not freeze the medicine. Once opened, the vial can be stored at room temperature (below 30°C) for up to 28 days (or 4 weeks). After this period, the vial should be discarded, even if there is still insulin remaining. Keep the medicine protected from light and out of the reach of children.