Cinod 5 Mg Tablet (20 Tab)

CINOD 5 MG TABLET

CINOD 5 MG TABLET, manufactured by Ajanta Pharma Limited, is a medication primarily used for the management of hypertension. It belongs to the class of calcium channel blockers.

Composition

Each film-coated tablet contains Cilnidipine 5 mg as the active ingredient.

Uses

CINOD 5 MG TABLET is prescribed for the following medical conditions:

• Hypertension (High Blood Pressure): It works by relaxing blood vessels, improving blood flow, and reducing the heart's workload, thereby lowering blood pressure.
• Prevention of Heart Attack and Stroke: By managing high blood pressure, it significantly reduces the risk of serious cardiovascular events.
• Angina (Chest Pain): It can be used to manage and prevent heart-related chest pain.
• It may also help improve vascular endothelial function, reduce proteinuria in hypertensive patients, and lower nocturnal blood pressure.

Dosage and Administration

For adults, the typical dosage is 5-10 mg once a day after breakfast. The dosage may be adjusted according to the patient's age and symptoms, and can be increased up to 20 mg once a day if a sufficient response is not achieved. For severe hypertension, 10-20 mg once daily after breakfast is recommended.

• CINOD 5 MG TABLET is for oral use.
• Take the tablet whole with a glass of water; do not crush, chew, or break it.
• It can be taken with or without food, but it is best to take it at the same time each day to maintain consistent control of blood pressure.
• Do not stop taking this medicine suddenly without consulting your doctor, as abrupt cessation can worsen your condition or cause a sudden increase in blood pressure.

Side Effects

Common side effects include:

• Headache, dizziness, sleepiness, fatigue, tiredness.
• Flushing (sense of warmth in the face, ears, neck, and trunk).
• Palpitations (fast heartbeat).
• Abdominal pain, nausea, constipation, stomach upset, changes in bowel habits.
• Peripheral edema (swelling in ankles, feet, or other body parts).
• Increased urination.
• Less common side effects can include rash, muscle pain, eye pain, and gingival hyperplasia (enlargement or overgrowth of the gums).

Precautions

• Contraindications: CINOD 5 MG TABLET is contraindicated in individuals with hypersensitivity to Cilnidipine or any of its excipients. It should not be administered to pregnant women or women who may be pregnant, or to nursing mothers.
• Liver and Kidney Conditions: Use with caution in patients with serious hepatic dysfunction (liver problems) or kidney problems, as plasma concentrations may become elevated.
• Heart Conditions: Administer with care in patients with a history of serious adverse reactions to calcium antagonists, severe hypotension (low blood pressure), edema, congestive heart failure, aortic stenosis, or those who have recently suffered a heart attack or have coronary artery disease.
• Dizziness: The medication may cause dizziness or lightheadedness, especially at the start of treatment or when increasing the dose. Patients should be cautious while operating machines or driving.
• Alcohol: Avoid or limit alcohol consumption as it may increase the blood pressure-lowering effect and dizziness.
• Grapefruit Juice: Avoid consuming grapefruit or grapefruit juice, as it can increase the blood concentration of Cilnidipine, potentially leading to excessive lowering of blood pressure and side effects.
• Drug Interactions: Inform your doctor about all medicines, herbal preparations, and supplements you are taking. Cilnidipine can interact with other hypotensive agents, Cimetidine, Rifampicin, Azole antifungal agents (e.g., itraconazole, miconazole), Digoxin, anticancer agents, antiepileptics, antibiotics, and antipsychotics.
• Children and Elderly: The safety of Cilnidipine in pediatric patients has not been established. In elderly patients, Cilnidipine should be administered carefully, possibly starting with a lower dose.
• Lactose: CINOD 5 MG TABLET contains lactose.

Storage

Store CINOD 5 MG TABLET in a cool, dry place, protected from direct sunlight, moisture, and heat. Keep it out of sight and reach of children. Ensure the tablets are stored below 30°C. Always check the expiry date and avoid using the medicine past its expiration date.

Here are some frequently asked questions about CINOD 5 MG TABLET:

What is CINOD 5 MG TABLET used for?

CINOD 5 MG TABLET is primarily used to treat high blood pressure (hypertension). It can also be used for associated vascular disorders, to protect end organs, and to help prevent conditions like heart attack and stroke. It may also be prescribed for the management of angina (chest pain related to heart issues).

How does CINOD 5 MG TABLET work?

CINOD 5 MG TABLET contains cilnidipine, which is a calcium channel blocker. It works by blocking both L-type and N-type calcium channels in the body. This action relaxes and widens blood vessels, which reduces the resistance to blood flow and lowers blood pressure. Additionally, it suppresses the release of norepinephrine, a hormone that can increase heart rate and blood pressure, providing an additional antihypertensive effect.

What is the usual dosage for CINOD 5 MG TABLET?

For adults, the typical dosage is 5-10 mg once a day, usually taken after breakfast. The dosage can be adjusted by a doctor based on the patient's age and symptoms, and can be increased up to 20 mg once daily if a sufficient response is not observed.

What are the possible side effects of CINOD 5 MG TABLET?

Common side effects include swelling of the ankles or other body parts (peripheral edema), headache, dizziness, flushing (redness and warmth of the skin), palpitations (fast heartbeat), nausea, stomach pain, constipation, fatigue, and gingival hyperplasia (enlargement or overgrowth of the gums). If any side effects persist or worsen, you should consult your doctor.

Is CINOD 5 MG TABLET safe during pregnancy or breastfeeding?

CINOD 5 MG TABLET is generally not recommended during pregnancy as it may harm the fetus. It is also advisable to avoid administration to nursing mothers, or if indispensable, to discontinue breastfeeding, as cilnidipine has been reported to transfer to mother's milk in animal experiments. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can CINOD 5 MG TABLET be taken with other medications?

CINOD 5 MG TABLET can interact with several medications. It is metabolized by the enzyme CYP3A4, so CYP3A4 inhibitors (e.g., itraconazole, ritonavir, clarithromycin) can increase its levels, while CYP3A4 inducers (e.g., rifampicin, phenytoin, carbamazepine) can decrease its effectiveness. Concomitant use with other antihypertensive agents, alpha-blockers, or digoxin may lead to an excessive decrease in blood pressure or increased plasma concentrations of digoxin. It is crucial to inform your doctor about all medicines and supplements you are taking.

What precautions should be taken while taking CINOD 5 MG TABLET?

Patients with serious hepatic (liver) dysfunction, severe kidney problems, severe low blood pressure (hypotension), or a history of serious adverse reactions to calcium antagonists should use this medicine with caution. Since it may cause dizziness, patients should be careful when operating machines or driving. Do not stop taking the medicine abruptly without consulting your doctor, as sudden withdrawal of a calcium antagonist can worsen certain symptoms or cause a sudden increase in blood pressure. Avoid consuming grapefruit or grapefruit juice, as it can increase the blood levels of cilnidipine and lead to potentially harmful side effects.

What happens if a dose of CINOD 5 MG TABLET is missed?

If you miss a dose of CINOD 5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should CINOD 5 MG TABLET be stored?

CINOD 5 MG TABLET should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. It should be kept out of the sight and reach of children. Always check the expiry date and avoid using the medicine past its expiration date.